Details for: Raf

Gene ID: 31221

Symbol: Raf

Ensembl ID: FBgn0003079

Description: Raf oncogene

Associated with

Other Information

Genular Protein ID: 1284333008

Symbol: KRAF1_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 3135183

Title: Proliferation of both somatic and germ cells is affected in the Drosophila mutants of raf proto-oncogene.

PubMed ID: 3135183

DOI: 10.1002/j.1460-2075.1988.tb02875.x

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 10731137

Title: From sequence to chromosome: the tip of the X chromosome of D. melanogaster.

PubMed ID: 10731137

DOI: 10.1126/science.287.5461.2220

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 12694293

Title: Contrasting selection pressures on components of the Ras-mediated signal transduction pathway in Drosophila.

PubMed ID: 12694293

DOI: 10.1046/j.1365-294x.2003.01741.x

PubMed ID: 3037346

Title: Drosophila melanogaster homologs of the raf oncogene.

PubMed ID: 3037346

DOI: 10.1128/mcb.7.6.2134-2140.1987

PubMed ID: 8423783

Title: Biochemical analysis of torso and D-raf during Drosophila embryogenesis: implications for terminal signal transduction.

PubMed ID: 8423783

DOI: 10.1128/mcb.13.2.1163-1172.1993

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

PubMed ID: 19965758

Title: The insect neuropeptide PTTH activates receptor tyrosine kinase torso to initiate metamorphosis.

PubMed ID: 19965758

DOI: 10.1126/science.1176450

PubMed ID: 29433126

Title: MEK drives BRAF activation through allosteric control of KSR proteins.

PubMed ID: 29433126

DOI: 10.1038/nature25478

Sequence Information:

  • Length: 739
  • Mass: 83729
  • Checksum: B685A895D05048C1
  • Sequence:
  • MSSESSTEGD SDLYDPLAEE LHNVQLVKHV TRENIDALNA KFANLQEPPA MYLIEYQELT 
    SKLHELEAKE QELMERLNSQ DQQEDSSLVE RFKEQPHYQN QTQILQQQRQ LARVHHGNDL 
    TDSLGSQPGS QCGTLTRQPK ILLRAHLPNQ QRTSVEVISG VRLCDALMKA LKLRQLTPDM 
    CEVSTTHSGR HIIPWHTDIG TLHVEEIFVR LLDKFPIRTH IKHQIIRKTF FSLVFCEGCR 
    RLLFTGFYCS QCNFRFHQRC ANRVPMLCQP FPMDSYYQLL LAENPDNGVG FPGRGTAVRF 
    NMSSRSRSRR CSSSGSSSSS KPPSSSSGNH RQGRPPRISQ DDRSNSAPNV CINNIRSVTS 
    EVQRSLIMQA RPPLPHPCTD HSNSTQASPT STLKHNRPRA RSADESNKNL LLRDAKSSEE 
    NWNILAEEIL IGPRIGSGSF GTVYRAHWHG PVAVKTLNVK TPSPAQLQAF KNEVAMLKKT 
    RHCNILLFMG CVSKPSLAIV TQWCEGSSLY KHVHVSETKF KLNTLIDIGR QVAQGMDYLH 
    AKNIIHRDLK SNNIFLHEDL SVKIGDFGLA TAKTRWSGEK QANQPTGSIL WMAPEVIRMQ 
    ELNPYSFQSD VYAFGIVMYE LLAECLPYGH ISNKDQILFM VGRGLLRPDM SQVRSDAPQA 
    LKRLAEDCIK YTPKDRPLFR PLLNMLENML RTLPKIHRSA SEPNLTQSQL QNDEFLYLPS 
    PKTPVNFNNF QFFGSAGNI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.