Details for: HLA DRB3
Associated with
Other Information
Genular Protein ID: 3742838844
Symbol: DRB3_HUMAN
Name: HLA class II histocompatibility antigen, DR beta 3 chain
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11894954
Title: Complete sequence of an HLA-DR beta chain deduced from a cDNA clone and identification of multiple non-allelic DR beta chain genes.
PubMed ID: 11894954
PubMed ID: 3459965
Title: Polymorphism of human Ia antigens: gene conversion between two DR beta loci results in a new HLA-D/DR specificity.
PubMed ID: 3459965
DOI: 10.1038/322067a0
PubMed ID: 9234492
Title: Description of two new HLA-DRB alleles (DRB1*0310 and DRB3*01012) found in a Spanish infant.
PubMed ID: 9234492
PubMed ID: 10902611
Title: DRB3 alleles with variations in the annealing sites of commonly used amplification primers.
PubMed ID: 10902611
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 6414998
Title: Molecular analysis of the genes for human class II antigens of the major histocompatibility complex.
PubMed ID: 6414998
PubMed ID: 3476943
Title: Allelic variation in the DR subregion of the human major histocompatibility complex.
PubMed ID: 3476943
PubMed ID: 11098940
Title: Identification by sequencing based typing and complete coding region analysis of three new HLA class II alleles: DRB3*0210, DRB3*0211 and DQB1*0310.
PubMed ID: 11098940
PubMed ID: 15140047
Title: Sequencing of two new HLA class II alleles: DRB3*0218 and DQB1*030202.
PubMed ID: 15140047
PubMed ID: 10958362
Title: Identification of a new DRB3*02 allelic variant (DRB3*0209) by high-resolution sequence-based typing.
PubMed ID: 10958362
PubMed ID: 11972885
Title: Description of fourteen new DRB alleles found in a stem cell donor registry.
PubMed ID: 11972885
PubMed ID: 15496209
Title: Three new DRB alleles routinely identified by sequence-based typing: DRB1*010103, DRB1*0326 and DRB3*0219.
PubMed ID: 15496209
PubMed ID: 18764810
Title: Characterisation of two novel HLA alleles, HLA-Cw*0429 and HLA-DRB3*0223.
PubMed ID: 18764810
PubMed ID: 19000136
Title: Description of three novel HLA-DRB3 alleles: DRB3*010105, DRB3*0112 and DRB3*0113.
PubMed ID: 19000136
PubMed ID: 9162096
Title: Diversity associated with the second expressed HLA-DRB locus in the human population.
PubMed ID: 9162096
PubMed ID: 9243765
Title: Identification of new DRB1*01 (DRB1*01022), DRB1*14 (DRB1*1428) and DRB3* (DRB3*0206) alleles.
PubMed ID: 9243765
PubMed ID: 9802612
Title: A novel DRB3 allele (DRB3*0208), a new allelic variant of DRB1*1502 (DRB1*15023) and two new DQB1 (DQB1*03012 and DQB1*0614) alleles.
PubMed ID: 9802612
PubMed ID: 11380956
Title: Identification of three new DRB3* (DRB3*0106, DRB3*0107 and DRB3*02022) alleles.
PubMed ID: 11380956
PubMed ID: 15104685
Title: Identification of three novel alleles: DRB3*0110, DRB1*1140, and DRB1*140102.
PubMed ID: 15104685
PubMed ID: 10599892
Title: New HLA class II alleles in the Indonesian population.
PubMed ID: 10599892
PubMed ID: 9234494
Title: Identification and nucleotide sequence of two novel DRB3 alleles, DRB3*0102 and DRB3*010133.
PubMed ID: 9234494
PubMed ID: 9389331
Title: Identification of a new DRB3*02 allele (DRB3*0207) by sequence-based typing.
PubMed ID: 9389331
PubMed ID: 2471740
Title: HLA-DR beta-chain polymorphism. Second domain polymorphism reflects evolutionary relatedness of alleles and may explain public serologic epitopes.
PubMed ID: 2471740
PubMed ID: 2788702
Title: Correlation of structure with T cell responses of the three members of the HLA-DRw52 allelic series.
PubMed ID: 2788702
PubMed ID: 2463305
Title: Delineation of several DR-restricted tetanus toxin T cell epitopes.
PubMed ID: 2463305
PubMed ID: 12944060
Title: Identification of HLA class II-restricted H-Y-specific T-helper epitope evoking CD4+ T-helper cells in H-Y-mismatched transplantation.
PubMed ID: 12944060
PubMed ID: 16148104
Title: Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes.
PubMed ID: 16148104
PubMed ID: 18305173
Title: MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation.
PubMed ID: 18305173
PubMed ID: 19494351
Title: Naturally processed peptides spanning the HPA-1a polymorphism are efficiently generated and displayed from platelet glycoprotein by HLA-DRB3*0101-positive antigen-presenting cells.
PubMed ID: 19494351
PubMed ID: 19706888
Title: Identification of 4 new HLA-DR-restricted minor histocompatibility antigens as hematopoietic targets in antitumor immunity.
PubMed ID: 19706888
PubMed ID: 19531622
Title: Vaccination with recombinant NY-ESO-1 protein elicits immunodominant HLA-DR52b-restricted CD4+ T cell responses with a conserved T cell receptor repertoire.
PubMed ID: 19531622
PubMed ID: 19535639
Title: Evidence for the specificity for platelet HPA-1a alloepitope and the presenting HLA-DR52a of diverse antigen-specific helper T cell clones from alloimmunized mothers.
PubMed ID: 19535639
PubMed ID: 19830726
Title: Reassessing the role of HLA-DRB3 T-cell responses: evidence for significant expression and complementary antigen presentation.
PubMed ID: 19830726
PubMed ID: 20368442
Title: Monitoring of NY-ESO-1 specific CD4+ T cells using molecularly defined MHC class II/His-tag-peptide tetramers.
PubMed ID: 20368442
PubMed ID: 23569328
Title: MHC II tetramers visualize human CD4+ T cell responses to Epstein-Barr virus infection and demonstrate atypical kinetics of the nuclear antigen EBNA1 response.
PubMed ID: 23569328
DOI: 10.1084/jem.20121437
PubMed ID: 22929521
Title: Identification of a Wilms' tumor 1-derived immunogenic CD4(+) T-cell epitope that is recognized in the context of common Caucasian HLA-DR haplotypes.
PubMed ID: 22929521
DOI: 10.1038/leu.2012.248
PubMed ID: 30282837
Title: Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy.
PubMed ID: 30282837
PubMed ID: 31020640
Title: Naturally processed HLA-DR3-restricted HHV-6B peptides are recognized broadly with polyfunctional and cytotoxic CD4 T-cell responses.
PubMed ID: 31020640
PubMed ID: 31333679
Title: Characterization of Magnitude and Antigen Specificity of HLA-DP, DQ, and DRB3/4/5 Restricted DENV-Specific CD4+ T Cell Responses.
PubMed ID: 31333679
PubMed ID: 31308093
Title: Primary EBV Infection Induces an Acute Wave of Activated Antigen-Specific Cytotoxic CD4+ T Cells.
PubMed ID: 31308093
PubMed ID: 32341563
Title: Analyzing the Mycobacterium tuberculosis immune response by T-cell receptor clustering with GLIPH2 and genome-wide antigen screening.
PubMed ID: 32341563
PubMed ID: 17583734
Title: Crystallographic structure of the human leukocyte antigen DRA, DRB3*0101: models of a directional alloimmune response and autoimmunity.
PubMed ID: 17583734
PubMed ID: 18697946
Title: The structure of HLA-DR52c: comparison to other HLA-DRB3 alleles.
PubMed ID: 18697946
PubMed ID: 23510415
Title: Common and well-documented HLA alleles: 2012 update to the CWD catalogue.
PubMed ID: 23510415
DOI: 10.1111/tan.12093
Sequence Information:
- Length: 266
- Mass: 29962
- Checksum: 2FC3AE68D3B10EAD
- Sequence:
MVCLKLPGGS SLAALTVTLM VLSSRLAFAG DTRPRFLELR KSECHFFNGT ERVRYLDRYF HNQEEFLRFD SDVGEYRAVT ELGRPVAESW NSQKDLLEQK RGRVDNYCRH NYGVGESFTV QRRVHPQVTV YPAKTQPLQH HNLLVCSVSG FYPGSIEVRW FRNGQEEKAG VVSTGLIQNG DWTFQTLVML ETVPRSGEVY TCQVEHPSVT SALTVEWRAR SESAQSKMLS GVGGFVLGLL FLGAGLFIYF RNQKGHSGLQ PTGFLS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.