Details for: HLA DRB4

Gene ID: 3126

Symbol: HLA DRB4

Description: major histocompatibility complex, class II, DR beta 4

Associated with

Other Information

Genular Protein ID: 2860704347

Symbol: DRB4_HUMAN

Name: HLA class II histocompatibility antigen, DR beta 4 chain

UniProtKB Accession Codes:

P13762 B0S863 O78042 P79664 Q29889 Q30163 Q6TLK6 Q860N4 Q861F3 Q8WLT9 Q9BS54

Database IDs:

AGR 1 AlphaFoldDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CDD 1 CTD 1 ChEMBL 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 EMBL 18 Ensembl 2 GO 18 Gene3D 1 GeneCards 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 PANTHER 2 PIR 3 PRO 1 PROSITE 2 PathwayCommons 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 7 RefSeq 2 SIGNOR 1 SMART 2 SMR 1 SUPFAM 2 SignaLink 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3110774

Title: Sequence and evolution of HLA-DR7- and -DRw53-associated beta-chain genes.

PubMed ID: 3110774

DOI: 10.1073/pnas.84.14.4929

PubMed ID: 11972878

Title: Specific amplification of the HLA-DRB4 gene from c-DNA. Complete coding sequence of the HLA alleles DRB4*0103101 and DRB4*01033.

PubMed ID: 11972878

DOI: 10.1034/j.1399-0039.2002.590108.x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3467350

Title: Evolutionary and genetic implications of sequence variation in two nonallelic HLA-DR beta-chain cDNA sequences.

PubMed ID: 3467350

DOI: 10.1073/pnas.84.1.209

PubMed ID: 3036826

Title: Class II genes of the human major histocompatibility complex. Organization and evolutionary relationship of the DR beta genes.

PubMed ID: 3036826

DOI: 10.1016/s0021-9258(18)47480-7

PubMed ID: 9234493

Title: Identification of a new DRB4 allele (DRB4*0105) by sequence-based typing.

PubMed ID: 9234493

DOI: 10.1111/j.1399-0039.1997.tb02819.x

PubMed ID: 8598037

Title: Invariant chain structure and MHC class II function.

PubMed ID: 8598037

DOI: 10.1016/s0092-8674(00)81025-9

PubMed ID: 11684289

Title: Presentation of antigens by MHC class II molecules: getting the most out of them.

PubMed ID: 11684289

DOI: 10.1016/s0161-5890(01)00069-4

PubMed ID: 17241953

Title: Autophagy in MHC class II presentation: sampling from within.

PubMed ID: 17241953

DOI: 10.1016/j.immuni.2007.01.005

PubMed ID: 18046453

Title: MHC class II molecules on the move for successful antigen presentation.

PubMed ID: 18046453

DOI: 10.1038/sj.emboj.7601945

PubMed ID: 18305173

Title: MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation.

PubMed ID: 18305173

DOI: 10.1073/pnas.0708874105

PubMed ID: 19117940

Title: The HLA-DRalpha chain is modified by polyubiquitination.

PubMed ID: 19117940

DOI: 10.1074/jbc.m805736200

PubMed ID: 19092054

Title: MHC class II transport at a glance.

PubMed ID: 19092054

DOI: 10.1242/jcs.035089

PubMed ID: 19533806

Title: CD74 in antigen presentation, inflammation, and cancers of the gastrointestinal tract.

PubMed ID: 19533806

DOI: 10.3748/wjg.15.2855

Sequence Information:

  • Length: 266
  • Mass: 29941
  • Checksum: 96FF5FE572403FAE
  • Sequence:
    • MVCLKLPGGS CMAALTVTLT VLSSPLALAG DTQPRFLEQA KCECHFLNGT ERVWNLIRYI 
YNQEEYARYN SDLGEYQAVT ELGRPDAEYW NSQKDLLERR RAEVDTYCRY NYGVVESFTV 
QRRVQPKVTV YPSKTQPLQH HNLLVCSVNG FYPGSIEVRW FRNGQEEKAG VVSTGLIQNG 
DWTFQTLVML ETVPRSGEVY TCQVEHPSMM SPLTVQWSAR SESAQSKMLS GVGGFVLGLL 
FLGTGLFIYF RNQKGHSGLQ PTGLLS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.