Details for: AOX1
Associated with
Other Information
Genular Protein ID: 3932043198
Symbol: AOXA_HUMAN
Name: Aldehyde oxidase 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8248161
Title: cDNA cloning, characterization, and tissue-specific expression of human xanthine dehydrogenase/xanthine oxidase.
PubMed ID: 8248161
PubMed ID: 11302742
Title: Mutation of human molybdenum cofactor sulfurase gene is responsible to classical xanthinuria type II.
PubMed ID: 11302742
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7786031
Title: Substrate specificity of human liver aldehyde oxidase toward substituted quinazolines and phthalazines: a comparison with hepatic enzyme from guinea pig, rabbit, and baboon.
PubMed ID: 7786031
PubMed ID: 9224775
Title: In vitro oxidation of famciclovir and 6-deoxypenciclovir by aldehyde oxidase from human, guinea pig, rabbit, and rat liver.
PubMed ID: 9224775
PubMed ID: 17022944
Title: Aldehyde oxidase 1 is highly abundant in hepatic steatosis and is down-regulated by adiponectin and fenofibric acid in hepatocytes in vitro.
PubMed ID: 17022944
PubMed ID: 18066686
Title: Mammalian aldehyde oxidases: genetics, evolution and biochemistry.
PubMed ID: 18066686
PubMed ID: 18671973
Title: Small-interference RNA-mediated knock-down of aldehyde oxidase 1 in 3T3-L1 cells impairs adipogenesis and adiponectin release.
PubMed ID: 18671973
PubMed ID: 20444863
Title: In vitro-in vivo correlation for intrinsic clearance for drugs metabolized by human aldehyde oxidase.
PubMed ID: 20444863
PubMed ID: 22031625
Title: Characterization of aldehyde oxidase enzyme activity in cryopreserved human hepatocytes.
PubMed ID: 22031625
PubMed ID: 22522748
Title: Hydralazine as a selective probe inactivator of aldehyde oxidase in human hepatocytes: estimation of the contribution of aldehyde oxidase to metabolic clearance.
PubMed ID: 22522748
PubMed ID: 22335465
Title: The role of aldehyde oxidase in drug metabolism.
PubMed ID: 22335465
PubMed ID: 22996261
Title: Evidence for substrate-dependent inhibition profiles for human liver aldehyde oxidase.
PubMed ID: 22996261
PubMed ID: 23857892
Title: Aldehyde oxidase 1 (AOX1) in human liver cytosols: quantitative characterization of AOX1 expression level and activity relationship.
PubMed ID: 23857892
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 26322824
Title: Structural insights into xenobiotic and inhibitor binding to human aldehyde oxidase.
PubMed ID: 26322824
PubMed ID: 26842593
Title: Optimization of the Expression of Human Aldehyde Oxidase for Investigations of Single-Nucleotide Polymorphisms.
PubMed ID: 26842593
PubMed ID: 22279051
Title: The impact of single nucleotide polymorphisms on human aldehyde oxidase.
PubMed ID: 22279051
Sequence Information:
- Length: 1338
- Mass: 147918
- Checksum: 2AB5E543F18C9261
- Sequence:
MDRASELLFY VNGRKVIEKN VDPETMLLPY LRKKLRLTGT KYGCGGGGCG ACTVMISRYN PITKRIRHHP ANACLIPICS LYGAAVTTVE GIGSTHTRIH PVQERIAKCH GTQCGFCTPG MVMSIYTLLR NHPEPTLDQL TDALGGNLCR CTGYRPIIDA CKTFCKTSGC CQSKENGVCC LDQGINGLPE FEEGSKTSPK LFAEEEFLPL DPTQELIFPP ELMIMAEKQS QRTRVFGSER MMWFSPVTLK ELLEFKFKYP QAPVIMGNTS VGPEVKFKGV FHPVIISPDR IEELSVVNHA YNGLTLGAGL SLAQVKDILA DVVQKLPEEK TQMYHALLKH LGTLAGSQIR NMASLGGHII SRHPDSDLNP ILAVGNCTLN LLSKEGKRQI PLNEQFLSKC PNADLKPQEI LVSVNIPYSR KWEFVSAFRQ AQRQENALAI VNSGMRVFFG EGDGIIRELC ISYGGVGPAT ICAKNSCQKL IGRHWNEQML DIACRLILNE VSLLGSAPGG KVEFKRTLII SFLFKFYLEV SQILKKMDPV HYPSLADKYE SALEDLHSKH HCSTLKYQNI GPKQHPEDPI GHPIMHLSGV KHATGEAIYC DDMPLVDQEL FLTFVTSSRA HAKIVSIDLS EALSMPGVVD IMTAEHLSDV NSFCFFTEAE KFLATDKVFC VGQLVCAVLA DSEVQAKRAA KRVKIVYQDL EPLILTIEES IQHNSSFKPE RKLEYGNVDE AFKVVDQILE GEIHMGGQEH FYMETQSMLV VPKGEDQEMD VYVSTQFPKY IQDIVASTLK LPANKVMCHV RRVGGAFGGK VLKTGIIAAV TAFAANKHGR AVRCVLERGE DMLITGGRHP YLGKYKAGFM NDGRILALDM EHYSNAGASL DESLFVIEMG LLKMDNAYKF PNLRCRGWAC RTNLPSNTAF RGFGFPQAAL ITESCITEVA AKCGLSPEKV RIINMYKEID QTPYKQEINA KNLIQCWREC MAMSSYSLRK VAVEKFNAEN YWKKKGLAMV PLKFPVGLGS RAAGQAAALV HIYLDGSVLV THGGIEMGQG VHTKMIQVVS RELRMPMSNV HLRGTSTETV PNANISGGSV VADLNGLAVK DACQTLLKRL EPIISKNPKG TWKDWAQTAF DESINLSAVG YFRGYESDMN WEKGEGQPFE YFVYGAACSE VEIDCLTGDH KNIRTDIVMD VGCSINPAID IGQIEGAFIQ GMGLYTIEEL NYSPQGILHT RGPDQYKIPA ICDMPTELHI ALLPPSQNSN TLYSSKGLGE SGVFLGCSVF FAIHDAVSAA RQERGLHGPL TLNSPLTPEK IRMACEDKFT KMIPRDEPGS YVPWNVPI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.