Mcm6 | FBgn0025815 | NCBI 31603

Details for: Mcm6

Gene ID: 31603

Symbol: Mcm6

Ensembl ID: FBgn0025815

Description: Minichromosome maintenance 6

Associated with

Activation of atr in response to replication stress
(R-DME-176187)
Activation of the pre-replicative complex
(R-DME-68962)
Assembly of the pre-replicative complex
(R-DME-68867)
Cell cycle
(R-DME-1640170)
Cell cycle, mitotic
(R-DME-69278)
Cell cycle checkpoints
(R-DME-69620)
Dna replication pre-initiation
(R-DME-69002)
G1/s transition
(R-DME-69206)
G2/m checkpoints
(R-DME-69481)
Mitotic g1 phase and g1/s transition
(R-DME-453279)
Orc1 removal from chromatin
(R-DME-68949)
S phase
(R-DME-69242)
Switching of origins to a post-replicative state
(R-DME-69052)
Synthesis of dna
(R-DME-69239)
3'-5' dna helicase activity
(GO:0043138)
Atp binding
(GO:0005524)
Cmg complex
(GO:0071162)
Dna binding
(GO:0003677)
Dna duplex unwinding
(GO:0032508)
Dna helicase activity
(GO:0003678)
Dna replication
(GO:0006260)
Dna replication initiation
(GO:0006270)
Dna unwinding involved in dna replication
(GO:0006268)
Double-strand break repair via break-induced replication
(GO:0000727)
Eggshell chorion gene amplification
(GO:0007307)
Mcm complex
(GO:0042555)
Mitotic dna replication
(GO:1902969)
Nucleus
(GO:0005634)
Single-stranded 3'-5' dna helicase activity
(GO:1990518)
Single-stranded dna binding
(GO:0003697)

Other Information

Proteins

DNA replication licensing factor Mcm6

Genular Protein ID: 1237859650

Symbol: MCM6_DROME

Name: DNA replication licensing factor Mcm6

UniProtKB Accession Codes:

Q9V461 O96047 Q960E3

Database IDs:

Citations:

PubMed ID: 9795205

Title: cDNA cloning and expression during development of Drosophila melanogaster MCM3, MCM6 and MCM7.

PubMed ID: 9795205

DOI: 10.1016/s0378-1119(98)00358-8

PubMed ID: 10023044

Title: Identification and complete cDNA sequence of the missing Drosophila MCMs: DmMCM3, DmMCM6 and DmMCM7.

PubMed ID: 10023044

DOI: 10.1016/s0378-1119(98)00596-4

PubMed ID: 11854416

Title: Drosophila minichromosome maintenance 6 is required for chorion gene amplification and genomic replication.

PubMed ID: 11854416

DOI: 10.1091/mbc.01-08-0400

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 16798881

Title: Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase.

PubMed ID: 16798881

DOI: 10.1073/pnas.0602400103

PubMed ID: 20122406

Title: Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins.

PubMed ID: 20122406

DOI: 10.1016/j.molcel.2009.12.030

Sequence Information:

Length: 817
Mass: 92353
Checksum: 0B7921FB3D888980
Sequence:

MDVADAQVGQ LRVKDEVGIR AQKLFQDFLE EFKEDGEIKY TRPAASLESP DRCTLEVSFE 
DVEKYDQNLA TAIIEEYYHI YPFLCQSVSN YVKDRIGLKT QKDCYVAFTE VPTRHKVRDL 
TTSKIGTLIR ISGQVVRTHP VHPELVSGVF MCLDCQTEIR NVEQQFKFTN PTICRNPVCS 
NRKRFMLDVE KSLFLDFQKI RIQETQAELP RGCIPRAVEI ILRSELVETV QAGDRYDFTG 
TLIVVPDVSV LAGVGTRAEN SSRHKPGEGM DGVTGLKALG MRELNYRMAF LACSVQATTA 
RFGGTDLPMS EVTAEDMKKQ MTDAEWHKIY EMSKDRNLYQ NLISSLFPSI YGNDEVKRGI 
LLQQFGGVAK TTTEKTSLRG DINVCIVGDP STAKSQFLKQ VSDFSPRAIY TSGKASSAAG 
LTAAVVRDEE SFDFVIEAGA LMLADNGICC IDEFDKMDQR DQVAIHEAME QQTISIARAG 
VRATLNARTS ILAAANPING RYDRSKSLQQ NIQLSAPIMS RFDLFFILVD ECNEVVDYAI 
ARKIVDLHSN IEESVERAYT REEVLRYVTF ARQFKPVISQ EAGHMLVENY GHLRQRDTGT 
SGRSTWRITV RQLESMIRLS EAMAKLECSN RVLERHVKEA FRLLNKSIIR VEQPDIHLDD 
DEGLDMDDGI QHDIDMENNG AAANVDENNG MDTSASGAVQ KKKFTLSFED YKNLSTMLVL 
HMRAEEARCE VEGNDTGIKR SNVVTWYLEQ VADQIESEDE LISRKNLIEK LIDRLIYHDQ 
VIIPLKTSTL KPRIQVQKDF VEEDDPLLVV HPNYVVE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Mcm6

Associated with

Other Information

cDNA cloning and expression during development of Drosophila melanogaster MCM3, MCM6 and MCM7. PubMed ID: 9795205

Identification and complete cDNA sequence of the missing Drosophila MCMs: DmMCM3, DmMCM6 and DmMCM7. PubMed ID: 10023044

Drosophila minichromosome maintenance 6 is required for chorion gene amplification and genomic replication. PubMed ID: 11854416

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila full-length cDNA resource. PubMed ID: 12537569

Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase. PubMed ID: 16798881

Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins. PubMed ID: 20122406