Details for: Pink1
Associated with
Other Information
Genular Protein ID: 1043286307
Symbol: PINK1_DROME
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10731132
Title: The genome sequence of Drosophila melanogaster.
PubMed ID: 10731132
PubMed ID: 12537572
Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.
PubMed ID: 12537572
PubMed ID: 12537569
Title: A Drosophila full-length cDNA resource.
PubMed ID: 12537569
PubMed ID: 16672980
Title: Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin.
PubMed ID: 16672980
DOI: 10.1038/nature04788
PubMed ID: 16672981
Title: Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin.
PubMed ID: 16672981
DOI: 10.1038/nature04779
PubMed ID: 16818890
Title: Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin.
PubMed ID: 16818890
PubMed ID: 16938835
Title: Antioxidants protect PINK1-dependent dopaminergic neurons in Drosophila.
PubMed ID: 16938835
PubMed ID: 18957282
Title: PINK1 controls mitochondrial localization of Parkin through direct phosphorylation.
PubMed ID: 18957282
PubMed ID: 19048081
Title: Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin.
PubMed ID: 19048081
DOI: 10.1242/dmm.000109
PubMed ID: 18443288
Title: Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery.
PubMed ID: 18443288
PubMed ID: 18799731
Title: The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila.
PubMed ID: 18799731
PubMed ID: 18230723
Title: The PINK1/Parkin pathway regulates mitochondrial morphology.
PubMed ID: 18230723
PubMed ID: 20194754
Title: Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin.
PubMed ID: 20194754
PubMed ID: 22645651
Title: Discovery of catalytically active orthologues of the Parkinson's disease kinase PINK1: analysis of substrate specificity and impact of mutations.
PubMed ID: 22645651
DOI: 10.1098/rsob.110012
PubMed ID: 22396657
Title: Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria.
PubMed ID: 22396657
PubMed ID: 23509287
Title: The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo.
PubMed ID: 23509287
PubMed ID: 24901221
Title: PINK1-mediated phosphorylation of Parkin boosts Parkin activity in Drosophila.
PubMed ID: 24901221
PubMed ID: 25474007
Title: Phosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tethering.
PubMed ID: 25474007
PubMed ID: 27906179
Title: PINK1-dependent phosphorylation of PINK1 and Parkin is essential for mitochondrial quality control.
PubMed ID: 27906179
PubMed ID: 28435104
Title: Drosophila PINK1 and parkin loss-of-function mutants display a range of non-motor Parkinson's disease phenotypes.
PubMed ID: 28435104
PubMed ID: 29563254
Title: Phosphorylation of MCAD selectively rescues PINK1 deficiencies in behavior and metabolism.
PubMed ID: 29563254
PubMed ID: 30772175
Title: PINK1 Inhibits Local Protein Synthesis to Limit Transmission of Deleterious Mitochondrial DNA Mutations.
PubMed ID: 30772175
PubMed ID: 32484300
Title: PINK1 phosphorylates Drp1S616 to regulate mitophagy-independent mitochondrial dynamics.
PubMed ID: 32484300
PubMed ID: 32138754
Title: PARIS induced defects in mitochondrial biogenesis drive dopamine neuron loss under conditions of parkin or PINK1 deficiency.
PubMed ID: 32138754
Sequence Information:
- Length: 721
- Mass: 80228
- Checksum: 9764EBF46B443F2E
- Sequence:
MSVRLLTVRL IKHGRYILRS YCKRDIHANI LDQNQLKTRS KRGFPLPSTA ANVLRTTPQQ AAKSVVNVVP RTINSPSGSP FNGSGSSPTS SSGIFRVGQH ARKLFIDNIL SRVTTTYSED LRQRATRKLF FGDSAPFFAL IGVSLASGSG VLSKEDELEG VCWEIREAAS RLQNAWNHDE ISDTLDSKFT IDDLEIGPPI AKGCAAVVYA ADFKKDVASD GASLHTDAQP QATPAFAPNS WSTHEMMSPL QNMSRFVHNF GGSVDNVFHY SQPSAASDFV GAQSREQDQR HHEQQQHQNQ EQEQHQNQEP SSSAFNVTSP ANSNINSSVD SYPLALKMMF NYDIQSNALS ILRAMYKETV PARQRGMNEA ADEWERLLQN QTVHLPRHPN IVCMFGFFCD EVRNFPDGHL LYPVAQPQRI NPQGYGRNMS LYLLMKRYDH SLRGLLDSQD LSTRNRILLL AQMLEAVNHL SRHGVAHRDL KSDNVLIELQ DDAAPVLVLS DFGCCLADKV HGLRLPYVSH DVDKGGNAAL MAPEIFNTMP GPFAVLNYGK ADLWACGALA YEIFGNRNPF YSSSGGMARE RGEMTLSLRN SDYRQDQLPP MSDACPPLLQ QLVYNILNPN PSKRVSPDIA ANVVQLFLWA PSNWLKAGGM PNSPEILQWL LSLTTKIMCE GRPQMGAGLM PVASCGNRRA YVEYLLICSF LARARLRRIR GALNWIQNVV A
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.