Details for: brk

Gene ID: 31665

Symbol: brk

Ensembl ID: FBgn0024250

Description: brinker

Associated with

  • Cell competition in a multicellular organism
    (GO:0035212)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Imaginal disc-derived wing morphogenesis
    (GO:0007476)
  • Negative regulation of bmp signaling pathway
    (GO:0030514)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleus
    (GO:0005634)
  • Posterior malpighian tubule development
    (GO:0061328)
  • Regulation of gene expression
    (GO:0010468)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Wing disc morphogenesis
    (GO:0007472)

Other Information

Genular Protein ID: 2491667832

Symbol: Q9XTN4_DROME

Name: N/A

UniProtKB Accession Codes:

Q9XTN4

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisProt 1 EMBL 8 EnsemblMetazoa 1 EvolutionaryTrace 1 ExpressionAtlas 1 FlyBase 2 GO 11 Gene3D 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PaxDb 1 Pfam 2 Proteomes 2 RefSeq 1 SAM 1 SMR 1 STRING 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10052457

Title: Transducing the Dpp morphogen gradient in the wing of Drosophila: regulation of Dpp targets by brinker.

PubMed ID: 10052457

DOI: 10.1016/S0092-8674(00)80659-5

PubMed ID: 10094047

Title: brinker is a target of Dpp in Drosophila that negatively regulates Dpp-dependent genes.

PubMed ID: 10094047

DOI: 10.1038/18451

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 16876822

Title: DNA recognition by the brinker repressor--an extreme case of coupling between binding and folding.

PubMed ID: 16876822

DOI: 10.1016/j.jmb.2006.06.045

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

PubMed ID: 26109357

Title: Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.

PubMed ID: 26109357

DOI: .1534/g3.115.018929

PubMed ID: 26109356

Title: Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.

PubMed ID: 26109356

DOI: .1534/g3.115.018937

PubMed ID: 25589440

Title: The Release 6 reference sequence of the Drosophila melanogaster genome.

PubMed ID: 25589440

Sequence Information:

  • Length: 704
  • Mass: 77514
  • Checksum: ECF542995CD98B11
  • Sequence:
    • MDSSSEQLNG SGALNFKRPK DSSENATNSH TNNGNSSGSP KMGSRRIFTP HFKLQVLESY 
RNDNDCKGNQ RATARKYNIH RRQIQKWLQC ESNLRSSVAN NQQQQQQQQQ QQQQQQQQQQ 
LLPQQSVSPT PAVKVFHQLS HPLVHQLHHH HAAAVGHHHH HAAHHHAAHH HHAAAAAAAA 
AAAAAAAAAH HHAAHHLLAA NGMVPHPLAA HPHLHVPVAM HPQMQHQKEQ QQQQQQLQQE 
QQQQDQQQSQ QETPATIATN GSNQGSSNVL SAAKIAAVVA AAMATSNGNP TPTATIPASS 
SSSSNTLPSS NNSSCHNSSS SSNSCNSNQV PIQVPILSGS PGSTSSASHI PHVPFAYHHN 
LHGYLENRLE AVATPAPMDL SLGSSARRQM QLHEKDPSGV DLTFRKRKVI TSPMQPDKIS 
KLEEVIKKEP ETETENEDVE VDVETEQPEE HKLPSKQVKL FKPYLLDDDE EQDHHHHHHH 
HRQEDLDEGA AEEEQDDEEE SRYADDDEVD SKEAADKKQR RLKKKPSAIN EQREPIIWSN 
HPYPGGCVSP GSSITSSFQC PTSMQQQQTF PVAGGSPNQQ FQDNCSSSKA TTPLSPFSAP 
ALSPTGFCCP KGSPVSGYES SSSTYSDSGS NYSLNLQLHA VYNDNLMYMQ QQQQQQQQQH 
HLQHQQHLQR WLDQESLATA RTSSVNRPLI LVADTAPTNL TLVA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.