Details for: Trxr1

Gene ID: 31760

Symbol: Trxr1

Ensembl ID: FBgn0020653

Description: Thioredoxin reductase 1

Associated with

Other Information

Genular Protein ID: 1793686236

Symbol: TRXR1_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9056265

Title: Molecular organization of the glutathione reductase gene in Drosophila melanogaster.

PubMed ID: 9056265

DOI: 10.1006/abbi.1996.9872

PubMed ID: 11158675

Title: Substitution of the thioredoxin system for glutathione reductase in Drosophila melanogaster.

PubMed ID: 11158675

DOI: 10.1126/science.291.5504.643

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 11525742

Title: Cooperative action of antioxidant defense systems in Drosophila.

PubMed ID: 11525742

DOI: 10.1016/s0960-9822(01)00393-1

PubMed ID: 11782468

Title: Methylseleninate is a substrate rather than an inhibitor of mammalian thioredoxin reductase. Implications for the antitumor effects of selenium.

PubMed ID: 11782468

DOI: 10.1074/jbc.m109234200

PubMed ID: 11796729

Title: Mitochondrial and cytoplasmic thioredoxin reductase variants encoded by a single Drosophila gene are both essential for viability.

PubMed ID: 11796729

DOI: 10.1074/jbc.m111692200

PubMed ID: 11877442

Title: Thioredoxin-2 but not thioredoxin-1 is a substrate of thioredoxin peroxidase-1 from Drosophila melanogaster: isolation and characterization of a second thioredoxin in D.melanogaster and evidence for distinct biological functions of Trx-1 and Trx-2.

PubMed ID: 11877442

DOI: 10.1074/jbc.m200636200

PubMed ID: 18211101

Title: Acid-base catalysis in the mechanism of thioredoxin reductase from Drosophila melanogaster.

PubMed ID: 18211101

DOI: 10.1021/bi702040u

PubMed ID: 18991392

Title: Function of Glu-469' in the acid-base catalysis of thioredoxin reductase from Drosophila melanogaster.

PubMed ID: 18991392

DOI: 10.1021/bi801449h

PubMed ID: 17385893

Title: Structural and biochemical studies reveal differences in the catalytic mechanisms of mammalian and Drosophila melanogaster thioredoxin reductases.

PubMed ID: 17385893

DOI: 10.1021/bi602394p

Sequence Information:

  • Length: 596
  • Mass: 64322
  • Checksum: 8DA6FC08CF6A7292
  • Sequence:
  • MNLCNSRFSV TFVRQCSTIL TSPSAGIIQN RGSLTTKVPH WISSSLSCAH HTFQRTMNLT 
    GQRGSRDSTG ATGGNAPAGS GAGAPPPFQH PHCDRAAMYA QPVRKMSTKG GSYDYDLIVI 
    GGGSAGLACA KEAVLNGARV ACLDFVKPTP TLGTKWGVGG TCVNVGCIPK KLMHQASLLG 
    EAVHEAAAYG WNVDEKIKPD WHKLVQSVQN HIKSVNWVTR VDLRDKKVEY INGLGSFVDS 
    HTLLAKLKSG ERTITAQTFV IAVGGRPRYP DIPGAVEYGI TSDDLFSLDR EPGKTLVVGA 
    GYIGLECAGF LKGLGYEPTV MVRSIVLRGF DQQMAELVAA SMEERGIPFL RKTVPLSVEK 
    QDDGKLLVKY KNVETGEEAE DVYDTVLWAI GRKGLVDDLN LPNAGVTVQK DKIPVDSQEA 
    TNVANIYAVG DIIYGKPELT PVAVLAGRLL ARRLYGGSTQ RMDYKDVATT VFTPLEYACV 
    GLSEEDAVKQ FGADEIEVFH GYYKPTEFFI PQKSVRYCYL KAVAERHGDQ RVYGLHYIGP 
    VAGEVIQGFA AALKSGLTIN TLINTVGIHP TTAEEFTRLA ITKRSGLDPT PASCCS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.