dsh | FBgn0000499 | NCBI 32078

Details for: dsh

Gene ID: 32078

Symbol: dsh

Ensembl ID: FBgn0000499

Description: dishevelled

Associated with

Apical cortex
(GO:0045179)
Axon extension
(GO:0048675)
Border follicle cell migration
(GO:0007298)
Canonical wnt signaling pathway
(GO:0060070)
Cell migration
(GO:0016477)
Compound eye morphogenesis
(GO:0001745)
Compound eye photoreceptor cell differentiation
(GO:0001751)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dorsal closure
(GO:0007391)
Epidermis morphogenesis
(GO:0048730)
Establishment of epithelial cell planar polarity
(GO:0090163)
Establishment of imaginal disc-derived wing hair orientation
(GO:0001737)
Establishment of mitotic spindle orientation
(GO:0000132)
Establishment of ommatidial planar polarity
(GO:0042067)
Establishment of planar polarity
(GO:0001736)
Female gonad development
(GO:0008585)
Follicle cell of egg chamber development
(GO:0030707)
Frizzled binding
(GO:0005109)
Germ-line stem-cell niche homeostasis
(GO:0060250)
Heart formation
(GO:0060914)
Imaginal disc-derived wing hair organization
(GO:0035317)
Imaginal disc-derived wing margin morphogenesis
(GO:0008587)
Intracellular signal transduction
(GO:0035556)
Motor neuron axon guidance
(GO:0008045)
Oogenesis
(GO:0048477)
Phosphatidic acid binding
(GO:0070300)
Plasma membrane
(GO:0005886)
Positive regulation of axon extension
(GO:0045773)
Positive regulation of axon guidance
(GO:1902669)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Regulation of actin filament bundle assembly
(GO:0032231)
Regulation of axonogenesis
(GO:0050770)
Regulation of compound eye pigmentation
(GO:0048076)
Regulation of tube length, open tracheal system
(GO:0035159)
Retinal ganglion cell axon guidance
(GO:0031290)
Salivary gland morphogenesis
(GO:0007435)
Segment polarity determination
(GO:0007367)
Signaling receptor complex adaptor activity
(GO:0030159)
Somatic stem cell population maintenance
(GO:0035019)
Synaptic target inhibition
(GO:0016201)
Wing and notum subfield formation
(GO:0035309)
Wnt signaling pathway
(GO:0016055)
Wnt signalosome
(GO:1990909)

Other Information

Proteins

Segment polarity protein dishevelled

Genular Protein ID: 3014704221

Symbol: DSH_DROME

Name: Segment polarity protein dishevelled

UniProtKB Accession Codes:

P51140 Q494J5 Q9VYZ9

Database IDs:

Citations:

PubMed ID: 8149913

Title: Dishevelled is required during wingless signaling to establish both cell polarity and cell identity.

PubMed ID: 8149913

DOI: 10.1242/dev.120.2.347

PubMed ID: 8288125

Title: The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal.

PubMed ID: 8288125

DOI: 10.1101/gad.8.1.118

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 7744250

Title: The dishevelled protein is modified by wingless signaling in Drosophila.

PubMed ID: 7744250

DOI: 10.1101/gad.9.9.1087

PubMed ID: 11274052

Title: Naked cuticle targets dishevelled to antagonize Wnt signal transduction.

PubMed ID: 11274052

DOI: 10.1101/gad.869201

PubMed ID: 12354775

Title: Zinc-dependent interaction between dishevelled and the Drosophila Wnt antagonist naked cuticle.

PubMed ID: 12354775

DOI: 10.1074/jbc.m203246200

PubMed ID: 16849595

Title: An unconventional nuclear localization motif is crucial for function of the Drosophila Wnt/wingless antagonist Naked cuticle.

PubMed ID: 16849595

DOI: 10.1534/genetics.106.061853

Sequence Information:

Length: 623
Mass: 68917
Checksum: 0BA24ED350666CF5
Sequence:

MDADRGGGQE TKVIYHIDDE TTPYLVKIPI PSAQVTLRDF KLVLNKQNNN YKYFFKSMDA 
DFGVVKEEIA DDSTILPCFN GRVVSWLVSA DGTNQSDNCS ELPTSECELG MGLTNRKLQQ 
QQQQHQQQQQ QQQQQHQQQQ QQQQQQVQPV QLAQQQQQQV LHHQKMMGNP LLQPPPLTYQ 
SASVLSSDLD STSLFGTESE LTLDRDMTDY SSVQRLQVRK KPQRRKKRAP SMSRTSSYSS 
ITDSTMSLNI ITVSINMEAV NFLGISIVGQ SNRGGDGGIY VGSIMKGGAV ALDGRIEPGD 
MILQVNDVNF ENMTNDEAVR VLREVVQKPG PIKLVVAKCW DPNPKGYFTI PRTEPVRPID 
PGAWVAHTQA LTSHDSIIAD IAEPIKERLD QNNLEEIVKA MTKPDSGLEI RDRMWLKITI 
PNAFIGADAV NWVLENVEDV QDRREARRIV SAMLRSNYIK HTVNKLTFSE QCYYVVNEER 
NPNLLGRGHL HPHQLPHGHG GHALSHADTE SITSDIGPLP NPPIYMPYSA TYNPSHGYQP 
IQYGIAERHI SSGSSSSDVL TSKDISASQS DITSVIHQAN QLTIAAHGSN KSSGSSNRGG 
GGGGGGGGNN TNDQDVSVFN YVL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: dsh

Associated with

Other Information

Dishevelled is required during wingless signaling to establish both cell polarity and cell identity. PubMed ID: 8149913

The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal. PubMed ID: 8288125

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

The dishevelled protein is modified by wingless signaling in Drosophila. PubMed ID: 7744250

Naked cuticle targets dishevelled to antagonize Wnt signal transduction. PubMed ID: 11274052

Zinc-dependent interaction between dishevelled and the Drosophila Wnt antagonist naked cuticle. PubMed ID: 12354775

An unconventional nuclear localization motif is crucial for function of the Drosophila Wnt/wingless antagonist Naked cuticle. PubMed ID: 16849595