Details for: APBA2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 245.4592
Cell Significance Index: -38.1800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 152.6158
Cell Significance Index: -38.7100 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 74.9771
Cell Significance Index: -30.4600 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 31.9458
Cell Significance Index: -30.5000 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 31.0473
Cell Significance Index: -38.2800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 9.8276
Cell Significance Index: -38.7800 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 3.7463
Cell Significance Index: 64.2000 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.7182
Cell Significance Index: 545.2600 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: 1.8606
Cell Significance Index: 24.8200 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 1.5939
Cell Significance Index: 19.7700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.5743
Cell Significance Index: 564.6900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.0772
Cell Significance Index: 745.0200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.9194
Cell Significance Index: 51.5900 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.8156
Cell Significance Index: 161.8600 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.7461
Cell Significance Index: 33.0000 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.7331
Cell Significance Index: 27.7600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.5394
Cell Significance Index: 17.2800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.4714
Cell Significance Index: 24.7500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3903
Cell Significance Index: 74.2800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.1846
Cell Significance Index: 166.6500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.1128
Cell Significance Index: 51.1900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.0494
Cell Significance Index: 1.0700 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0178
Cell Significance Index: 1.7600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0150
Cell Significance Index: 8.2100 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.0040
Cell Significance Index: 0.0800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.0102
Cell Significance Index: -1.6700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0147
Cell Significance Index: -0.9000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0154
Cell Significance Index: -29.0900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0157
Cell Significance Index: -0.5500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0187
Cell Significance Index: -34.5600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0203
Cell Significance Index: -31.1800 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0240
Cell Significance Index: -0.5100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0296
Cell Significance Index: -40.2400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0467
Cell Significance Index: -29.6400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0467
Cell Significance Index: -34.2300 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.0486
Cell Significance Index: -0.5300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0530
Cell Significance Index: -39.2600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0563
Cell Significance Index: -42.6000 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0594
Cell Significance Index: -1.7100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0726
Cell Significance Index: -40.9200 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0747
Cell Significance Index: -33.0100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0775
Cell Significance Index: -10.6400 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.0877
Cell Significance Index: -1.7600 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0887
Cell Significance Index: -4.4800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1117
Cell Significance Index: -32.1300 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.1130
Cell Significance Index: -14.4800 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.1192
Cell Significance Index: -4.8900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.1198
Cell Significance Index: -3.0000 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.1306
Cell Significance Index: -3.6500 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.1315
Cell Significance Index: -1.6400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.1338
Cell Significance Index: -24.1200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.1398
Cell Significance Index: -15.2100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1413
Cell Significance Index: -24.1200 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.1669
Cell Significance Index: -2.3900 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.1820
Cell Significance Index: -5.9600 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.1831
Cell Significance Index: -8.3000 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.1867
Cell Significance Index: -3.9900 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.1897
Cell Significance Index: -3.2800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2096
Cell Significance Index: -44.1500 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.2141
Cell Significance Index: -6.8200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.2201
Cell Significance Index: -27.0600 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.2364
Cell Significance Index: -30.5400 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2389
Cell Significance Index: -34.7300 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: -0.2947
Cell Significance Index: -3.0700 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -0.2985
Cell Significance Index: -2.8400 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.3007
Cell Significance Index: -3.8000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.3229
Cell Significance Index: -22.3300 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.3304
Cell Significance Index: -38.9600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.3421
Cell Significance Index: -34.9500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.3510
Cell Significance Index: -40.9000 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.3637
Cell Significance Index: -7.5900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3721
Cell Significance Index: -38.7400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.3878
Cell Significance Index: -23.2800 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.3909
Cell Significance Index: -9.7500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3939
Cell Significance Index: -45.1300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.4495
Cell Significance Index: -15.6200 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.4607
Cell Significance Index: -16.1400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.4779
Cell Significance Index: -36.6800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.4990
Cell Significance Index: -37.1900 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.5249
Cell Significance Index: -11.3400 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.5297
Cell Significance Index: -37.4700 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.5330
Cell Significance Index: -25.0500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.5598
Cell Significance Index: -29.1600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.5617
Cell Significance Index: -36.2400 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.5703
Cell Significance Index: -11.8300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.5754
Cell Significance Index: -29.8900 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.6184
Cell Significance Index: -4.1900 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.6220
Cell Significance Index: -10.4100 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.6270
Cell Significance Index: -13.7300 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: -0.6459
Cell Significance Index: -8.1500 - Cell Name: neuron (CL0000540)
Fold Change: -0.6593
Cell Significance Index: -6.2500 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.6844
Cell Significance Index: -13.4700 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: -0.7138
Cell Significance Index: -5.4800 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.7427
Cell Significance Index: -18.5200 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.7529
Cell Significance Index: -22.1800 - Cell Name: neural cell (CL0002319)
Fold Change: -0.8383
Cell Significance Index: -9.7800 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.8859
Cell Significance Index: -55.8400 - Cell Name: astrocyte (CL0000127)
Fold Change: -0.9279
Cell Significance Index: -10.6200 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.9543
Cell Significance Index: -35.0300 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: -0.9644
Cell Significance Index: -10.6400
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3676391037
Symbol: APBA2_HUMAN
Name: Amyloid-beta A4 precursor protein-binding family A member 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9614075
Title: The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion.
PubMed ID: 9614075
PubMed ID: 9890987
Title: Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein.
PubMed ID: 9890987
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9395480
Title: Mints, Munc18-interacting proteins in synaptic vesicle exocytosis.
PubMed ID: 9395480
PubMed ID: 9110174
PubMed ID: 10833507
Title: Regulation of X11L-dependent amyloid precursor protein metabolism by XB51, a novel X11L-binding protein.
PubMed ID: 10833507
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
Sequence Information:
- Length: 749
- Mass: 82512
- Checksum: C15AE9CFAEF51D85
- Sequence:
MAHRKLESVG SGMLDHRVRP GPVPHSQEPE SEDMELPLEG YVPEGLELAA LRPESPAPEE QECHNHSPDG DSSSDYVNNT SEEEDYDEGL PEEEEGITYY IRYCPEDDSY LEGMDCNGEE YLAHSAHPVD TDECQEAVEE WTDSAGPHPH GHEAEGSQDY PDGQLPIPED EPSVLEAHDQ EEDGHYCASK EGYQDYYPEE ANGNTGASPY RLRRGDGDLE DQEEDIDQIV AEIKMSLSMT SITSASEASP EHGPEPGPED SVEACPPIKA SCSPSRHEAR PKSLNLLPEA KHPGDPQRGF KPKTRTPEER LKWPHEQVCN GLEQPRKQQR SDLNGPVDNN NIPETKKVAS FPSFVAVPGP CEPEDLIDGI IFAANYLGST QLLSERNPSK NIRMMQAQEA VSRVKRMQKA AKIKKKANSE GDAQTLTEVD LFISTQRIKV LNADTQETMM DHALRTISYI ADIGNIVVLM ARRRMPRSAS QDCIETTPGA QEGKKQYKMI CHVFESEDAQ LIAQSIGQAF SVAYQEFLRA NGINPEDLSQ KEYSDIINTQ EMYNDDLIHF SNSENCKELQ LEKHKGEILG VVVVESGWGS ILPTVILANM MNGGPAARSG KLSIGDQIMS INGTSLVGLP LATCQGIIKG LKNQTQVKLN IVSCPPVTTV LIKRPDLKYQ LGFSVQNGII CSLMRGGIAE RGGVRVGHRI IEINGQSVVA TAHEKIVQAL SNSVGEIHMK TMPAAMFRLL TGQETPLYI
Genular Protein ID: 841521375
Symbol: Q59G28_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 752
- Mass: 82769
- Checksum: 7309ABB550871C43
- Sequence:
TTAMAHRKLE SVGSGMLDHR VRPGPVPHSQ EPESEDMELP LEGYVPEGLE LAALRPESPA PEEQECHNHS PDGDSSSDYV NNTSEEEDYD EGLPEEEEGI TYYIRYCPED DSYLEGMDCN GEEYLAHSAH PVDTDECQEA VEEWTDSAGP HPHGHEAEGS QDYPDGQLPI PEDEPSVLEA HDQEEDGHYC ASKEGYQDYY PEEANGNTGA SPYRLRRGDG DLEDQEEDID QIVAEIKMSL SMTSITSASE ASPEHGPEPG PEDSVEACPP IKASCSPSRH EARPKSLNLL PEAKHPGDPQ RGFKPKTRTP EERPKWPHEQ VCNGLEQPRK QQRSDLNGPV DNNNIPETKK VASFPSFVAV PGPCEPEDLI DGIIFAANYL GSTQLLSERN PSKNIRMMQA QEAVSRVKRM QKAAKIKKKA NSEGDAQTLT EVDLFISTQR IKVLNADTQE TMMDHALRTI SYIADIGNIV VLMARRRMPR SASQDCIETT PGAQEGKKQY KMICHVFESE DAQLIAQSIG QAFSVAYQEF LRANGINPED LSQKEYSDII NTQEMYNDDL IHFSNSENCK ELQLEKHKGE ILGVVVVESG WGSILPTVIL ANMMNGGPAA RSGKLSIGDQ IMSINGTSLV GLPLATCQGI IKGLKNQTQV KLNIVSCPPV TTVLIKRPDL KYQLGFSVQN GIICSLMRGG IAERGGVRVG HRIIEINGQS VVATAHEKIV QALSNSVGEI HMKTMPAAMF RLLTGQETPL YI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.