Upf1 | FBgn0030354 | NCBI 32153

Details for: Upf1

Gene ID: 32153

Symbol: Upf1

Ensembl ID: FBgn0030354

Description: Upf1 RNA helicase

Associated with

Cellular responses to stimuli
(R-DME-8953897)
Cellular responses to stress
(R-DME-2262752)
Cellular response to chemical stress
(R-DME-9711123)
Cytoprotection by hmox1
(R-DME-9707564)
Metabolism
(R-DME-1430728)
Metabolism of lipids
(R-DME-556833)
Metabolism of rna
(R-DME-8953854)
Nonsense-mediated decay (nmd)
(R-DME-927802)
Nonsense mediated decay (nmd) enhanced by the exon junction complex (ejc)
(R-DME-975957)
Nonsense mediated decay (nmd) independent of the exon junction complex (ejc)
(R-DME-975956)
Regulation of lipid metabolism by pparalpha
(R-DME-400206)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Cellular response to hypoxia
(GO:0071456)
Cytoplasm
(GO:0005737)
Dna binding
(GO:0003677)
Dna duplex unwinding
(GO:0032508)
Double-stranded dna helicase activity
(GO:0036121)
Helicase activity
(GO:0004386)
Hydrolase activity
(GO:0016787)
Messenger ribonucleoprotein complex
(GO:1990124)
Mirna-mediated post-transcriptional gene silencing
(GO:0035195)
Neuronal ribonucleoprotein granule
(GO:0071598)
Nuclear-transcribed mrna catabolic process, nonsense-mediated decay
(GO:0000184)
Positive regulation of nuclear-transcribed mrna catabolic process, nonsense-mediated decay
(GO:2000624)
Regulatory ncrna-mediated post-transcriptional gene silencing
(GO:0035194)
Rna binding
(GO:0003723)
Rna helicase activity
(GO:0003724)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Regulator of nonsense transcripts 1 homolog

Genular Protein ID: 1895815228

Symbol: RENT1_DROME

Name: Regulator of nonsense transcripts 1 homolog

UniProtKB Accession Codes:

Q9VYS3 Q95RG9

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 12881430

Title: Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways.

PubMed ID: 12881430

DOI: 10.1093/emboj/cdg371

PubMed ID: 16199763

Title: Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets.

PubMed ID: 16199763

DOI: 10.1261/rna.2160905

PubMed ID: 17178403

Title: Staufen- and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P bodies.

PubMed ID: 17178403

DOI: 10.1016/j.neuron.2006.10.028

Sequence Information:

Length: 1180
Mass: 129913
Checksum: 150EAA970D221D0E
Sequence:

MSVDTYAPSS ALSFLDMDDN ELLPGADTQP TQYDYRDFTM PSTSQSQTQN DQLEIAQRCS 
AGDSHPRLAS ITNDLADLQF EEEDDEPGSS YVKELPPHAC KYCGIHDPAT VVMCNNCRKW 
FCNGRGSTSG SHIINHLVRA KHREVTLHGE GPLGETILEC YSCGVRNVFV LGFIPAKADS 
VVVLLCRQPC AAQNSLKDMN WDQEQWKPLI ADRCFLAWLV KQPSEQGQLR ARQISAAQIN 
KLEELWKENI EATFQDLEKP GIDSEPAHVL LRYEDGYQYE KTFGPLVRLE AEYDQKLKES 
ATQENIEVRW DVGLNKKTIA YFTLAKTDSD MKLMHGDELR LHYVGELYNP WSEIGHVIKV 
PDNFGDDVGL ELKSSTNAPV KCTSNFTVDF IWKCTSFDRM TRALCKFAID RNSVSNFIYS 
RLLGHGRADS NDEVLFRGPQ PKLFSAPHLP DLNRSQVYAV KHALQRPLSL IQGPPGTGKT 
VTSATIVYQL VKLHGGTVLV CAPSNTAVDQ LTEKIHRTNL KVVRVCAKSR EAIDSPVSFL 
ALHNQIRNME TNSELKKLQQ LKDETGELSS ADEKRYRNLK RAAENQLLEA ADVICCTCVG 
AGDGRLSRVK FTSILIDESM QSTEPECMVP VVLGAKQLIL VGDHCQLGPV VMCKKAARAG 
LSQSLFERLV VLGIRPFRLE VQYRMHPELS QFPSNFFYEG SLQNGVCAED RRLKLDFPWP 
QPERPMFFLV TQGQEEIAGS GTSFLNRTEA ANVEKITTRF LKAGIKPEQI GIITPYEGQR 
AYLVQYMQYQ GSLHSRLYQE IEIASVDAFQ GREKDIIIMS CVRSNERQGI GFLNDPRRLN 
VALTRAKFGI IIVGNPKVLA KQQLWNHLLN FYKDRKVLVE GSLNNLKESL IHFQKPKKLV 
NSMNIGAHFM STIIADAKEV MVPGSIYDRS GGYGQGRQMV GQSMNGGQYG GSGGGPYGNS 
PLGYGTPSSN SMVGFGLGNG GNGAAGGNNN FGGAGPSWAA AHLHHDSIGY ISNEHGAAAL 
GNMPVPVGMF MNMSNIPPRF YNQHQQAIMA VKQNRAIQQQ TGNFSPGNSG PGVTGVGVGR 
SATPGGNKKT NKLGKSRVTG GGTGGAPLTQ GSSVCNAAPY SQHPMPLSLQ MTQPSGFALS 
QQPELSQDFG QISQMDGLLS QDVAFNASGE RSLNQFSQPY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Upf1

Associated with

Other Information

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila full-length cDNA resource. PubMed ID: 12537569

Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways. PubMed ID: 12881430

Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets. PubMed ID: 16199763