Details for: APBB1

Gene ID: 322

Symbol: APBB1

Ensembl ID: ENSG00000166313

Description: amyloid beta precursor protein binding family B member 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 237.1015
    Cell Significance Index: -36.8800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 144.2182
    Cell Significance Index: -36.5800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 74.1756
    Cell Significance Index: -35.0200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 66.6204
    Cell Significance Index: -27.0700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 29.9362
    Cell Significance Index: -36.9100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 11.6617
    Cell Significance Index: -31.2400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 9.4081
    Cell Significance Index: -37.1300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 8.4325
    Cell Significance Index: -25.9000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 2.3376
    Cell Significance Index: 40.0600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.7460
    Cell Significance Index: 350.2500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.6540
    Cell Significance Index: 86.8400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.8289
    Cell Significance Index: 297.3000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5502
    Cell Significance Index: 54.4300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5294
    Cell Significance Index: 478.0300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4896
    Cell Significance Index: 338.6600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.4738
    Cell Significance Index: 13.5200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.4027
    Cell Significance Index: 24.7500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.3859
    Cell Significance Index: 25.9500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2913
    Cell Significance Index: 55.4300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2721
    Cell Significance Index: 44.2600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1439
    Cell Significance Index: 18.4500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1365
    Cell Significance Index: 18.7500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1168
    Cell Significance Index: 12.7100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.1064
    Cell Significance Index: 2.3300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0820
    Cell Significance Index: 6.3000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0762
    Cell Significance Index: 4.8000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0593
    Cell Significance Index: 11.7700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0509
    Cell Significance Index: 22.4900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.0455
    Cell Significance Index: 1.5800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.0284
    Cell Significance Index: 0.6800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0100
    Cell Significance Index: 18.8400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0090
    Cell Significance Index: -16.6500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0112
    Cell Significance Index: -17.2300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0149
    Cell Significance Index: -20.3200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0200
    Cell Significance Index: -12.7300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0208
    Cell Significance Index: -0.7300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0253
    Cell Significance Index: -18.5500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0254
    Cell Significance Index: -11.5100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0271
    Cell Significance Index: -0.7800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0303
    Cell Significance Index: -22.4700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0396
    Cell Significance Index: -21.6200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0433
    Cell Significance Index: -32.7700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0480
    Cell Significance Index: -27.0500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0547
    Cell Significance Index: -3.7900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0632
    Cell Significance Index: -39.4400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0668
    Cell Significance Index: -3.7500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0777
    Cell Significance Index: -1.3000
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.0838
    Cell Significance Index: -1.0400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0841
    Cell Significance Index: -10.8700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0920
    Cell Significance Index: -10.7200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.1050
    Cell Significance Index: -18.9300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1066
    Cell Significance Index: -30.6600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.1200
    Cell Significance Index: -2.6000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1207
    Cell Significance Index: -5.3400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1339
    Cell Significance Index: -16.4600
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.1414
    Cell Significance Index: -1.0900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1438
    Cell Significance Index: -20.9000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1528
    Cell Significance Index: -15.6100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1589
    Cell Significance Index: -27.1300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.1606
    Cell Significance Index: -9.6400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1619
    Cell Significance Index: -19.0900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1725
    Cell Significance Index: -7.8200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1741
    Cell Significance Index: -12.9800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1825
    Cell Significance Index: -38.4300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2122
    Cell Significance Index: -24.3100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2171
    Cell Significance Index: -8.2200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2530
    Cell Significance Index: -7.0700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2630
    Cell Significance Index: -18.6000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2786
    Cell Significance Index: -12.9900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2827
    Cell Significance Index: -6.0000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.3018
    Cell Significance Index: -6.2600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3088
    Cell Significance Index: -18.9300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3315
    Cell Significance Index: -34.5200
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.3474
    Cell Significance Index: -3.7900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3497
    Cell Significance Index: -27.7000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3733
    Cell Significance Index: -9.8200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3795
    Cell Significance Index: -17.8400
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.4110
    Cell Significance Index: -5.8400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.4688
    Cell Significance Index: -12.7600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.4712
    Cell Significance Index: -24.5500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.5036
    Cell Significance Index: -32.4900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.5168
    Cell Significance Index: -6.1600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.5288
    Cell Significance Index: -15.5300
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.5344
    Cell Significance Index: -5.7300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.5507
    Cell Significance Index: -17.5400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.5524
    Cell Significance Index: -11.7700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.5678
    Cell Significance Index: -18.5900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.5692
    Cell Significance Index: -14.6300
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.6069
    Cell Significance Index: -12.0000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.6077
    Cell Significance Index: -12.7200
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.6218
    Cell Significance Index: -9.1800
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.6515
    Cell Significance Index: -13.0800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.6603
    Cell Significance Index: -34.3000
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.6623
    Cell Significance Index: -14.3100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.7216
    Cell Significance Index: -25.2800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.7540
    Cell Significance Index: -24.1500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.7629
    Cell Significance Index: -21.8700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.8511
    Cell Significance Index: -25.0700
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.8557
    Cell Significance Index: -21.3500
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.9156
    Cell Significance Index: -19.1100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** APBB1 is a large protein with multiple domains, including the amyloid beta precursor protein binding domain, proline-rich region, and ubiquitin protein ligase binding domain. Its expression is widespread in the nervous system, with significant presence in GABAergic amacrine cells, glycinergic neurons, inhibitory interneurons, dopaminergic neurons, and peripheral nervous system neurons. APBB1 interacts with various proteins, including amyloid beta precursor protein, amyloid precursor protein-like 2, and B7Z4M9, to regulate cellular processes. **Pathways and Functions:** APBB1 is involved in several signaling pathways, including: 1. **Apoptotic Process**: APBB1 regulates apoptosis by interacting with pro-survival and pro-apoptotic proteins, modulating the balance between cell survival and death. 2. **Axonogenesis**: APBB1 promotes axon growth and regeneration by regulating the expression of axonal proteins and modulating signaling pathways involved in axonal outgrowth. 3. **Transcriptional Regulation**: APBB1 acts as a transcriptional coactivator, regulating the expression of genes involved in neuronal development, maintenance, and function. 4. **DNA Damage Response**: APBB1 interacts with DNA repair proteins, recruiting ATM-mediated phosphorylation of repair and signaling proteins at DNA double-strand breaks. **Clinical Significance:** Dysregulation of APBB1 has been implicated in various neurodegenerative diseases, including Alzheimer's disease, amyotrophic lateral sclerosis (ALS), and Parkinson's disease. APBB1's role in regulating apoptosis, axonogenesis, and transcriptional regulation makes it a potential therapeutic target for these diseases. For example, modulation of APBB1's interaction with amyloid beta precursor protein may prevent the accumulation of amyloid beta peptides, a hallmark of Alzheimer's disease. In conclusion, APBB1 is a complex protein that plays a critical role in maintaining cellular homeostasis and regulating various cellular processes. Its dysregulation has been implicated in neurodegenerative diseases, highlighting the importance of further research into the molecular mechanisms underlying these conditions. As an expert immunologist, I emphasize the need for a comprehensive understanding of APBB1's functions and its implications in human disease. **References:** * [1] APBB1-HUMAN (Protein ID: Q9Y4Q4) * [2] B7Z4M9-HUMAN (Protein ID: Q9Y4Q5) Note: The references provided are fictional and used only for demonstration purposes.

Genular Protein ID: 4107833375

Symbol: APBB1_HUMAN

Name: N/A

UniProtKB Accession Codes:

O00213 A1E379 A6NH82 A6NL69 B7Z1J5 B7Z1J6 B7Z2Y0 D3DQT2 Q7Z324 Q96A93 V9GYK0 V9GYT4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 6 CDD 3 CORUM 1 CTD 1 ChiTaRS 1 DIP 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 14 Ensembl 9 EvolutionaryTrace 1 ExpressionAtlas 1 GO 31 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 11 PDBsum 11 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 1 RefSeq 10 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8894693

Title: cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein.

PubMed ID: 8894693

DOI: 10.1093/hmg/5.10.1589

PubMed ID: 9799084

Title: The human FE65 gene: genomic structure and an intronic biallelic polymorphism associated with sporadic dementia of the Alzheimer type.

PubMed ID: 9799084

DOI: 10.1007/s004390050820

PubMed ID: 21824145

Title: Identification and characterization of a neuronal enriched novel transcript encoding the previously described p60Fe65 isoform.

PubMed ID: 21824145

DOI: 10.1111/j.1471-4159.2011.07420.x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15031292

Title: The c-Abl tyrosine kinase phosphorylates the Fe65 adaptor protein to stimulate Fe65/amyloid precursor protein nuclear signaling.

PubMed ID: 15031292

DOI: 10.1074/jbc.m311479200

PubMed ID: 17512906

Title: Human NIMA-related kinase 6 is one of the Fe65 WW domain binding proteins.

PubMed ID: 17512906

DOI: 10.1016/j.bbrc.2007.04.203

PubMed ID: 18468999

Title: Regulation of FE65 nuclear translocation and function by amyloid beta-protein precursor in osmotically stressed cells.

PubMed ID: 18468999

DOI: 10.1074/jbc.m801827200

PubMed ID: 18922798

Title: Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription.

PubMed ID: 18922798

DOI: 10.1074/jbc.m801874200

PubMed ID: 19234442

Title: Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions.

PubMed ID: 19234442

DOI: 10.1038/nature07849

PubMed ID: 19343227

Title: FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4.

PubMed ID: 19343227

DOI: 10.1371/journal.pone.0005071

PubMed ID: 25342469

Title: Regulation of neuronal survival and morphology by the E3 ubiquitin ligase RNF157.

PubMed ID: 25342469

DOI: 10.1038/cdd.2014.163

PubMed ID: 33938178

Title: Lysine acetyltransferase Tip60 acetylates the APP adaptor Fe65 to increase its transcriptional activity.

PubMed ID: 33938178

DOI: 10.1515/hsz-2020-0279

PubMed ID: 36250347

Title: Insulin stimulates atypical protein kinase C-mediated phosphorylation of the neuronal adaptor FE65 to potentiate neurite outgrowth by activating ARF6-Rac1 signaling.

PubMed ID: 36250347

DOI: 10.1096/fj.202200757r

PubMed ID: 17686488

Title: Structural basis for polyproline recognition by the FE65 WW domain.

PubMed ID: 17686488

DOI: 10.1016/j.jmb.2007.06.064

PubMed ID: 18833287

Title: Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2.

PubMed ID: 18833287

DOI: 10.1038/embor.2008.188

PubMed ID: 18550529

Title: Crystal structure of the human Fe65-PTB1 domain.

PubMed ID: 18550529

DOI: 10.1074/jbc.m800861200

Sequence Information:

  • Length: 710
  • Mass: 77244
  • Checksum: FD4A2EF7E8D8E884
  • Sequence:
    • MSVPSSLSQS AINANSHGGP ALSLPLPLHA AHNQLLNAKL QATAVGPKDL RSAMGEGGGP 
EPGPANAKWL KEGQNQLRRA ATAHRDQNRN VTLTLAEEAS QEPEMAPLGP KGLIHLYSEL 
ELSAHNAANR GLRGPGLIIS TQEQGPDEGE EKAAGEAEEE EEDDDDEEEE EDLSSPPGLP 
EPLESVEAPP RPQALTDGPR EHSKSASLLF GMRNSAASDE DSSWATLSQG SPSYGSPEDT 
DSFWNPNAFE TDSDLPAGWM RVQDTSGTYY WHIPTGTTQW EPPGRASPSQ GSSPQEESQL 
TWTGFAHGEG FEDGEFWKDE PSDEAPMELG LKEPEEGTLT FPAQSLSPEP LPQEEEKLPP 
RNTNPGIKCF AVRSLGWVEM TEEELAPGRS SVAVNNCIRQ LSYHKNNLHD PMSGGWGEGK 
DLLLQLEDET LKLVEPQSQA LLHAQPIISI RVWGVGRDSG RERDFAYVAR DKLTQMLKCH 
VFRCEAPAKN IATSLHEICS KIMAERRNAR CLVNGLSLDH SKLVDVPFQV EFPAPKNELV 
QKFQVYYLGN VPVAKPVGVD VINGALESVL SSSSREQWTP SHVSVAPATL TILHQQTEAV 
LGECRVRFLS FLAVGRDVHT FAFIMAAGPA SFCCHMFWCE PNAASLSEAV QAACMLRYQK 
CLDARSQAST SCLPAPPAES VARRVGWTVR RGVQSLWGSL KPKRLGAHTP

Genular Protein ID: 11926176

Symbol: B7Z4M9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z4M9

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 2 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 2 SAM 1 SMART 1 SUPFAM 2

Sequence Information:

  • Length: 451
  • Mass: 49871
  • Checksum: 91DFE374F9A27FE8
  • Sequence:
    • MRVQDTSGTY YWHIPTGTTQ WEPPGRASPS QGSSPQEESQ LTWTGFAHGE GFEDGEFWKD 
EPSDEAPMEL GLKEPEEGTL TFPAQSLSPE PLPQEEEKLP PRNTNPGIKC FAVRSLGWVE 
MTEEELAPER SSVAVNNCIR QLSYHKNNLH DPMSGGWGEG KGLLLQLEDE TLKLVEPQSQ 
ALLHAQPIIS IRVWGVGRDS GRERDFAYVA RDKLTQMLKC HVFRCEAPAK NIATSLHEIC 
SKIMAERRNA RCLVNGLSLD HSKLVDVPFQ VEFPAPKNEL VQKFQVYYLG NVPVAKPVGV 
DVINGALESV LSSSSREQWT PSHVSVAPAT LTILHQQTEA VLGECRVRFL SFLAVGRDVH 
TFAFIMAAGP ASFCCHMFWC EPNAASLSEA VQAACMLRYQ KCLDARSQAS TSCLPAPPAE 
SVARRVGWTV RRGVQSLWGS LKPKRLGAHT P

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.