Details for: hiw

Gene ID: 32429

Symbol: hiw

Ensembl ID: FBgn0030600

Description: highwire

Associated with

Other Information

Genular Protein ID: 3133451898

Symbol: HIW_DROME

Name: Protein pam/highwire/rpm-1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10839352

Title: Highwire regulates synaptic growth in Drosophila.

PubMed ID: 10839352

DOI: 10.1016/s0896-6273(00)81166-6

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 17697379

Title: DFsn collaborates with Highwire to down-regulate the Wallenda/DLK kinase and restrain synaptic terminal growth.

PubMed ID: 17697379

DOI: 10.1186/1749-8104-2-16

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

PubMed ID: 21874015

Title: Drosophila Rae1 controls the abundance of the ubiquitin ligase Highwire in post-mitotic neurons.

PubMed ID: 21874015

DOI: 10.1038/nn.2922

Sequence Information:

  • Length: 5233
  • Mass: 565631
  • Checksum: E5220FFDC91A58E7
  • Sequence:
  • MVGLLNPLKY GDHFYELYTN STRRKMQHDR KVLTKRKSRK DKSAAAMAAA AAAAVLEGNA 
    GAGGLVNPLD PPLVKEQLMI LPSFPVAHIE LDPNASKFAV FSAIRSTVLE AETRYSLFQE 
    GGAPSGQSGS NQKKWSNNVN SACCMMCAHS CMISNLLDCS CHAHMAMHGA VGPGNAGPGG 
    PVGVLVDGRI PAPVPVVVGG PGLPAEKRPR RDSANSDADS DTEEPTEREP VYATVPLIVG 
    AGLRSLFELI ADARHVHPLL CTKALKALLD VIQGQQPESF KLEPEELINP LYDLLLDLAT 
    MPAALNSATG AEANWSAMAC AALLGLCIAR GDTGKMLKAI AAMLMTPRQL SAQIVQLPVV 
    LATLQHTVIS AALNKPTRPD FHSHGVPHNS LIDEFPVKLP PLSTGAPITS PAMACDGVFV 
    YLLYGGTLLK IGTGFGGSYK GHIYAQNEDF SHERSAWLGY SGGQLYFRRT CRRSAGDQLQ 
    MVGLDTLAIK AMSPLSMLHM REGLNYVLFT DDDSLHAICS NRDDTLVVKK LNLYHNSYNI 
    DPPPFELPLQ LARKKFRTLG YAAFEDELLN QYQIQRIQSA HNSFEPKLPA PCRDADVDVM 
    GMACGKEFGL VRASNGRVYY YGKSAALGLK CVGRTPTLKL TELVISKAAN IVHVAVGHDG 
    IHALLVNDDG TVFFAGTARR GEDGDSSKNR RQPKAVKPKK MTKIDGHVVV HAACNNGTSA 
    FVTKTGKLIM YGKDTAHCDA MGFVSELLEQ HVTKVALGKA HCVALNAKGQ LFSFGLNNKG 
    QCGRIFNKLQ PVKDVPPFAS SSTAAACFAS LLPLDKRLKL DFSTLCDYDD HNLVQGQCRV 
    CVICRECTGY NVSCVSALNV PLDQRLAGSI CPCGHGDAGC AKCGLCAACI ALQDSDEAKT 
    ELKPPPSDVQ QRQQRSKTLI MRRKERKGEL ETGAAGGGAA TPTDLDKDPP RVAPLAPQLL 
    QLTSSSPVVQ VACGLHHTVV LTLAGEVYTF GSNQYGQLGS GDLQPVSGPV RVQVPGAISQ 
    VAAGSNHTVL LTSKGMVYTF GNYQKGQLGR LPSDYGLKPP PQDDDSPVGA GSDGGAGGSP 
    TVAPVGMPGP ERSQSPANVQ PSGSKEMPPL LPVLTQRQKF LWNCSPGAVF GLGPCYGKKV 
    TWIGANGDQT FIKIDESLIT AQMLPKMHVV ANKKTILLIP SIPLSFHTLS INRRDGSCTA 
    HYRGQTNFVK LMQAQPEQQQ PEINSNLDVA VTPVADSPAH ASTSSLLAAL TGTATAGVPI 
    NEQMSRSMHE ARNQIFEEQL PEVGSSAAAA AVAAPGTPVS AGSVPRSRRG GKQGTSSPEP 
    IPSPPQLAFT MDPTYNVLWV FDGAARKLRC HNVVASDIND SDANAATYRS LLSPELSLPD 
    RVDSRVARSQ ASLNLLACLD ILTSAQDNIP GCFEQPLLKQ TQQTAETQAG EFQVVNRFDN 
    FGGGWGYSGH SVEAIRFSAD TDIVICGFGM FGGRGEYSCK LKLFDLGGDG GGYEKEGILI 
    SETKEVPYEC GARSKHHILL PKPVSAVAGR WYLVWARIAG PSSDCGSCGQ ASVTTEDQVV 
    FSFKSSKKAN NGTDVNSGQI PAILYRLVTQ DCKQTPAQMD ADPVQRISRA FANSVSRECF 
    ESLVVLLSWS WDCFKLQLRE ERDRSRPLQL QQSLQYLGYV IKSCLRLLRK YTIEIYPQRN 
    SSTSVATGGG SNAAHGSGVV TTAKSVQSKP NKDKNTPRVV GNAGVMAKYF GDPSTSVAPA 
    MISSASSGGA PSTSASAAVA PGSGTPVTRK TNMENIQLAE CIGNVRALLI GIFCDDIFKD 
    IATDEGYELS LEILDECHLS FVACFDAFYP TSSLKWNCLC DLLAQMDRGA LHSRLLSAIL 
    AGLCSPSVKL RATFSLLSAA GNERQSIISP SDNSGLPMLS STDAHPYPVL VEQMIYRTQQ 
    EKSDFLSNSW TFKDVLVRLL DIIASPIRSR IEAIYSRSLG SLGYPGGKDC VNQGLIDNCC 
    HLLARVLAEI VYQTAMGEYD KLFMPPRTLH STGARFARCD VSRTWNTGNF GPDAIAFAVD 
    RPGVAIAGAM VYSGSGSYDY QLELLYDNTA DLQPQHKWET LESVSGSYDQ DAVHNDLAEI 
    KFDHPVHIKE NARYALRLCS QGARTCSGDA GMPAVRGPCG AQFHFYACDL SFNGTTPARG 
    QLPCILYYST PMKQDGHSAS GRTGDGSNVA THLEDRIMLL GPHEVSTRDT ALQIAADITK 
    KCTELLILAR NAMAASCSPS DNSSNHTQTI DSEHNITPIE EHMDINWANN SRTAALPTAI 
    DPQLSTARDL GKRIESFSKG LMETLKFDKR STNPFEMEIE IGATEVEESA DLRNGQSQSV 
    SQSQSQSQSV PINGNERTAD FEFAEQSAQQ SMPQHLHSDS EEAPLEVAGM AAGGGVSVAD 
    GSGGVAGVGS QAAAVQLLEV FNLAASNMFH TLLPLVYAHI ANLACSDPKS SVQILGLIKE 
    ILPHIAALNQ LHVSKDQRQP EPAIFATQTS GSGNSNSSST TSNHYCVVES DHPYKSASIS 
    SYRVEFPPCV QWLTIEFDPQ CGTAQLEDYL LLSIPMRPAS QAPPVPHVDD YLEQADNNVN 
    GAGDRRRNTG GGIAGSGAAP NTHQRSASVQ LTMASCCRSP GCGNAPGSAA APSSMPLRSQ 
    DPNDREWIVV KKFNTASTWL HNVLILPGNC VEFSLETASL YAQDPHNNRY GFKCLVVGYD 
    NPTSINASNS CLIRLEQELA YLGGMCSANL MKKELNLPDD KDVEDMSGIE ETINTHHTLL 
    SKGFALSEPQ LTVHQALESY LPIGSQSNER QFLKDFISGA PGSSGARLAA WLQPESRLDP 
    NKCELNTITE PLRYGWPSQV TVTIRDQYGD AVLVPELKVE IKAIPTGSGP NGSATGTGTS 
    CTSVAEVSAP GPNLWMRRAS RDTWGWGGMA PPPRINYEPT VKDKMVFKAI TFMKPYANYS 
    FEELRYASPV QTRVTELLNA KDMEDGTFSV QWTPSSVGAY CLAVTIDGIP LEEVYRVDVK 
    EGILPPPTQR NSAQRRPQAP SKLRRFQARH SSGLRIRSHP TLQSEQVGVV RVGGVISFID 
    EIENDDGVWL RLSTESIRQH CTMGWYPTEA WCLQFNQHLA RMLLQPVTDK EVNPVRKGVG 
    AEEDVEEQPP VTPSASGEAS PEPEPDPSPV LSPAKTKPGR FLSGHQSTNP FLYPAKHADL 
    AEREAQVQEE REKEEEQVDD EDADDREPEQ EALPAVELLP AHIGSAIAGV VGGGAIKLQA 
    LQKWFKGDAV DGPQPLTPSH SPPLAGVSVR ELVRAMGGQD SPRGNGNRSQ QEQDPEFSLA 
    SMRRPNYSAS QTAALLSTPK HTPKRSAVVA SETSGLEDEL SLLQITTTTT GQGEQQSELQ 
    LATTSTASSA SKRNPMGPIK RAMPPSFAES IRAVFAALLW HEGVVHDAMA CASFLKFHPG 
    LPKEGATVVT RRGESGDPRL QLSREQKAQQ RHSVEVANAG NYLNIRPSTL ETLTKSGNCS 
    LHNRSKYRKN LLSGGGGAIN SGDDTAQKLQ ALPEMVSVLP PALRCLVYLW EQICSGCVQI 
    VQSNALEQRE PRLLSPGSRD LNGDADTEGK EGKNSDQASA GEKDLGRKCK RKKKDDGSWC 
    EICELFLPMP VTYHMRIAHP GCGKSAKGKG YNSVGIFCEG WAGNCGEGGK GASSWFLMCD 
    PCRDRYLASC RSANNINSAA RQLESSAAEG NELNLFGVKS TTLIANAEVY TTMRENATFL 
    LELCSSSSSA SGAAGSLAAT SSSSKRSPQQ MSVVAMPVVI EHQLGNSDLK PSTSRCSRMA 
    RLSGSKFCPG VGSGAFRKSF VGGPPTAPEN VWLAPESFAC LECLGTAGHE DLPYEMFGLG 
    PNSNDNGYDR PLSEISYESC EPNNYDMLSG SLAPGTTAAA SVGGGNLSKF HRSYSMGQGW 
    ASLAQHNHPP PHHPQQQHHQ QQQMNLQLQQ HQAPPVDGQP KVVYRRRNNS TSEGDGSLLI 
    CYPSEHLRRL VPQKLLASVS VMQTASGEGT GKDHATGTLG LDQSAGQNGG GNLLLTRPAM 
    AFITQKHELD RLRAAMRRSL RIAACRIYAL QALNWLLRSV TQGVCLHDLM WWFVSSLNPT 
    GGHQPVERGE EASEPALEHP VAYTQISGRF AHLITQSLHV FLQSVADLTL HLPLGSPLQR 
    VAIQCFGIRF RQADHQFLHS SHVFGNISKI LSKSDEQNDA MAVSTILKPD CDVEHNQVHS 
    VATGGSSGAG ARLLCYTDLA GMFEVTVSSR PAMAESLTDN STETFWESDE EDRNKCKIIE 
    LSLTKLNYAC RYLLVHIDNS RDIQNKVLNV VFYAGQSLGD TNIIKSADVD PKACSWISAK 
    ICDDSCTHFR LELHGPENTL RVRQIKLLGL PIGGAVGSDD SSDHKHQPHL RLSHASRIQQ 
    QICEAETLRV FRLITGQVFG KLISNVSSDL VPPDSAGIGP PSGGAASTSL LADSLDLREH 
    MVGILFSRSK LSHLQKQVIV HIVHAIRKEA QRAKEDWELA NLAHVLKQSP QQQTAPALAA 
    SASCESTPER SRAPDTYCFE MLSMVLALSG SVVGRSYLSQ QHGLLRDLLG LLHTGSDRVQ 
    RQVTALLRRI LPEITPESFA ELLGVQRLPP ADYSIAHQSA SDFDMSRLGL LDIFLAVIAK 
    SLQLQVKVKT TVASTGPSGS GGVSGSSSGN GGAVLKAGQQ EKTPAFVRLW SSLDLSVQQL 
    RSRPPTGEPG TTDPFQFDAL PPRKESKRNL NQRWFLNGVI STKQAESIIS LIRDLASGKL 
    SEKWSQITKA AIAESVLNLT RLEEIYRSPE HCTKTSTLWL ALASLCVLER DHVEKLSSGQ 
    WSKLCDTRPL CSNHDDGETA AIIQCETCGS LCGDCDRFLH LNRKTRSHKR TVCKEEEEAI 
    RVELHESCGR TKLFWLLALA DSKTLKAMVE FRDGSHTIIS GPQEAVGRCR FCGLTGNSGL 
    LEIGNVCADA QCQEYAANSC LKTKPCGHAC GGVTGERKCL PCLQHVCHTR ENELAEELRD 
    PKLTQDADDM CMICFVEALS CAPSIHLECG HVFHYHCCKA VLEKRWSGPR ITFGFSLCPI 
    CKADIQHPLL SDILEPINGL KQDVKRKALM RIKYEGVVKD TDSKNVNMTQ LAMDRYAYYV 
    CFKCQKAYYG GEARCDAEIG EKFDPEELVC GGCSDVARAQ MCPKHGTDFL EYKCRYCCSV 
    AVFFCFGTTH FCDTCHDDFQ RLTNIPKVKL PQCPAGPKAK QLLGDECPLH VMHPPTGEEF 
    ALGCGVCRNA QTF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.