Details for: Top1

Gene ID: 32458

Symbol: Top1

Ensembl ID: FBgn0004924

Description: Topoisomerase 1

Associated with

Other Information

Genular Protein ID: 247968242

Symbol: TOP1_DROME

Name: DNA topoisomerase 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1335568

Title: Isolation and characterization of a gene encoding DNA topoisomerase I in Drosophila melanogaster.

PubMed ID: 1335568

DOI: 10.1093/nar/20.23.6177

PubMed ID: 8769417

Title: Isolation and characterization of a Drosophila gene essential for early embryonic development and formation of cortical cleavage furrows.

PubMed ID: 8769417

DOI: 10.1083/jcb.134.4.923

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 10885744

Title: Essential functions of DNA topoisomerase I in Drosophila melanogaster.

PubMed ID: 10885744

DOI: 10.1006/dbio.2000.9704

PubMed ID: 14871887

Title: Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein.

PubMed ID: 14871887

DOI: 10.1074/jbc.m310097200

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

Sequence Information:

  • Length: 972
  • Mass: 111688
  • Checksum: 3764B8BDEEFA30CD
  • Sequence:
  • MSGDVAAENS IHIQNGGSCE VVQSNGVTTN GHGHHHHHHS SSSSSSKHKS SSKDKHRDRE 
    REHKSSNSSS SSKEHKSSSR DKDRHKSSSS SSKHRDKDKE RDGSSNSHRS GSSSSHKDKD 
    GSSSSKHKSS SGHHKRSSKD KERRDKDKDR GSSSSSRHKS SSSSRDKERS SSSHKSSSSS 
    SSSKSKHSSS RHSSSSSSKD HPSYDGVFVK PEPVSQQLMH SGSVDAFQMQ QLGSYEAAAA 
    GTNFNGNGNV AGANYKNGYE ESIVDIKKEE ESFNNLSQAS SCDYSMSQFR ADEPPFVVKH 
    EQSYAEEDST MNYNDHDDDA DEMNDDEEDV PLAMRKRKQE ATDRPDGGMD NDDDDDIPLL 
    ARKKVKKEKI KKESKEKSKK RVKEEPSDDY GNVKPKKKKM KKEPEPAVSP GKRQKAKAKV 
    EEEEVWRWWE EEKRADGVKW STLEHKGPVF APRYERVPRN VRFYYDGKPL ELSEETEEAA 
    TFYAKMLNHD YCTKEVFNNN FFKDFRKSMT PREREIIKDF RKCNFQEMFN YFQAESEKRK 
    AASKEEKLIK KNENEALMKE FGFCMIDGHK EKIGNFRLEP PGLFRGRGEH PKMGMIKRRI 
    QASDVSINCG KDSKVPSPPP GSRWKEVRHD NTVTWLASWI ENVQGQVKYI MLNPSSKLKG 
    EKDHIKYETA RRLDKVIDKI RATYRDEWKS KEMRVRQRAV ALYFIDKLAL RAGNEKDEDQ 
    ADTVGCCSLR VEHVQLHKEL NGKENVVVFD FPGKDSIRYY NEVEVEKRVF KNLELFMEHK 
    KEGDDLFDRL NTQVLNEHLK ELMEGLTAKV FRTYNASKTL QSQLDLLTDP SATVPEKLLA 
    YNRANRAVAI LCNHQRSVPK SHEKSMENLK EKIKAKREAI EKCESEYHSR DEKKGKQLER 
    LRDQLKKLEL QETDRDENKT IALGTSKLNY LDPRISVAWC KKHDVPIEKI FNKTQRTKFL 
    WAVHMADENY RF

Genular Protein ID: 2448522299

Symbol: X2JKD2_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 593
  • Mass: 69971
  • Checksum: 679A6964404126D9
  • Sequence:
  • MLRSWVALRP FEKQSVCLVL GQRMLAVATV AGKRRRVRRK SVQEEQIRWW EEEKRADGVK 
    WSTLEHKGPV FAPRYERVPR NVRFYYDGKP LELSEETEEA ATFYAKMLNH DYCTKEVFNN 
    NFFKDFRKSM TPREREIIKD FRKCNFQEMF NYFQAESEKR KAASKEEKLI KKNENEALMK 
    EFGFCMIDGH KEKIGNFRLE PPGLFRGRGE HPKMGMIKRR IQASDVSINC GKDSKVPSPP 
    PGSRWKEVRH DNTVTWLASW IENVQGQVKY IMLNPSSKLK GEKDHIKYET ARRLDKVIDK 
    IRATYRDEWK SKEMRVRQRA VALYFIDKLA LRAGNEKDED QADTVGCCSL RVEHVQLHKE 
    LNGKENVVVF DFPGKDSIRY YNEVEVEKRV FKNLELFMEH KKEGDDLFDR LNTQVLNEHL 
    KELMEGLTAK VFRTYNASKT LQSQLDLLTD PSATVPEKLL AYNRANRAVA ILCNHQRSVP 
    KSHEKSMENL KEKIKAKREA IEKCESEYHS RDEKKGKQLE RLRDQLKKLE LQETDRDENK 
    TIALGTSKLN YLDPRISVAW CKKHDVPIEK IFNKTQRTKF LWAVHMADEN YRF

Genular Protein ID: 3892415558

Symbol: M9NDX3_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 970
  • Mass: 111575
  • Checksum: 8FFB0AD2A6DAB578
  • Sequence:
  • MTDAQSIHIQ NGGSCEVVQS NGVTTNGHGH HHHHHHSSSS SSSSKHKSSS KDKHRDRERE 
    HKSSNSSSSS KEHKSSSRDK DRHKSSSSSS KHRDKDKERD GSSNSHRSGS SSSHKDKDGS 
    SSSKHKSSSG HHKRSSKDKE RRDKDKDRGS SSSSRHKSSS SSRDKERSSS SHKSSSSSSS 
    SKSKHSSSRH SSSSSSKDQP SYDGVFVKPE PVSQQLMHSG SVDAFQMQQL GSYEAAAAGT 
    NFNGNGNVAG ANYKNGYEES IVDIKKEEES FNNLSQASSC DYSMSQFRAD EPPFVVKHEQ 
    SYAEEDSTMN YNDHDDDADE MNDDEEDVPL AMRKRKQEAT DRPDGGMDND DDDDIPLLAR 
    KKVKKEKIKK ESKEKSKKRV KEEPSDDYGN VKPKKKKMKK EPEPAVSPGK RQKAKAKVEE 
    EEVWRWWEEE KRADGVKWST LEHKGPVFAP RYERVPRNVR FYYDGKPLEL SEETEEAATF 
    YAKMLNHDYC TKEVFNNNFF KDFRKSMTPR EREIIKDFRK CNFQEMFNYF QAESEKRKAA 
    SKEEKLIKKN ENEALMKEFG FCMIDGHKEK IGNFRLEPPG LFRGRGEHPK MGMIKRRIQA 
    SDVSINCGKD SKVPSPPPGS RWKEVRHDNT VTWLASWIEN VQGQVKYIML NPSSKLKGEK 
    DHIKYETARR LDKVIDKIRA TYRDEWKSKE MRVRQRAVAL YFIDKLALRA GNEKDEDQAD 
    TVGCCSLRVE HVQLHKELNG KENVVVFDFP GKDSIRYYNE VEVEKRVFKN LELFMEHKKE 
    GDDLFDRLNT QVLNEHLKEL MEGLTAKVFR TYNASKTLQS QLDLLTDPSA TVPEKLLAYN 
    RANRAVAILC NHQRSVPKSH EKSMENLKEK IKAKREAIEK CESEYHSRDE KKGKQLERLR 
    DQLKKLELQE TDRDENKTIA LGTSKLNYLD PRISVAWCKK HDVPIEKIFN KTQRTKFLWA 
    VHMADENYRF

Genular Protein ID: 2775469678

Symbol: Q494M1_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

PubMed ID: 26109357

Title: Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.

PubMed ID: 26109357

DOI: .1534/g3.115.018929

PubMed ID: 26109356

Title: Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.

PubMed ID: 26109356

DOI: .1534/g3.115.018937

PubMed ID: 25589440

Title: The Release 6 reference sequence of the Drosophila melanogaster genome.

PubMed ID: 25589440

Sequence Information:

  • Length: 974
  • Mass: 111903
  • Checksum: 71E599BDCB136C90
  • Sequence:
  • MSGDVAAENS IHIQNGGSCE VVQSNGVTTN GHGHHHHHHH SSSSSSSSKH KSSSKDKHRD 
    REREHKSSNS SSSSKEHKSS SRDKDRHKSS SSSSKHRDKD KERDGSSNSH RSGSSSSHKD 
    KDGSSSSKHK SSSGHHKRSS KDKERRDKDK DRGSSSSSRH KSSSSSRDKE RSSSSHKSSS 
    SSSSSKSKHS SSRHSSSSSS KDQPSYDGVF VKPEPVSQQL MHSGSVDAFQ MQQLGSYEAA 
    AAGTNFNGNG NVAGANYKNG YEESIVDIKK EEESFNNLSQ ASSCDYSMSQ FRADEPPFVV 
    KHEQSYAEED STMNYNDHDD DADEMNDDEE DVPLAMRKRK QEATDRPDGG MDNDDDDDIP 
    LLARKKVKKE KIKKESKEKS KKRVKEEPSD DYGNVKPKKK KMKKEPEPAV SPGKRQKAKA 
    KVEEEEVWRW WEEEKRADGV KWSTLEHKGP VFAPRYERVP RNVRFYYDGK PLELSEETEE 
    AATFYAKMLN HDYCTKEVFN NNFFKDFRKS MTPREREIIK DFRKCNFQEM FNYFQAESEK 
    RKAASKEEKL IKKNENEALM KEFGFCMIDG HKEKIGNFRL EPPGLFRGRG EHPKMGMIKR 
    RIQASDVSIN CGKDSKVPSP PPGSRWKEVR HDNTVTWLAS WIENVQGQVK YIMLNPSSKL 
    KGEKDHIKYE TARRLDKVID KIRATYRDEW KSKEMRVRQR AVALYFIDKL ALRAGNEKDE 
    DQADTVGCCS LRVEHVQLHK ELNGKENVVV FDFPGKDSIR YYNEVEVEKR VFKNLELFME 
    HKKEGDDLFD RLNTQVLNEH LKELMEGLTA KVFRTYNASK TLQSQLDLLT DPSATVPEKL 
    LAYNRANRAV AILCNHQRSV PKSHEKSMEN LKEKIKAKRE AIEKCESEYH SRDEKKGKQL 
    ERLRDQLKKL ELQETDRDEN KTIALGTSKL NYLDPRISVA WCKKHDVPIE KIFNKTQRTK 
    FLWAVHMADE NYRF

Genular Protein ID: 498462904

Symbol: Q8IR39_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 581
  • Mass: 68641
  • Checksum: 3FC6AC5390166302
  • Sequence:
  • MPYNRKNFFC QEPEPAVSPG KRQKAKAKVE EEEVWRWWEE EKRADGVKWS TLEHKGPVFA 
    PRYERVPRNV RFYYDGKPLE LSEETEEAAT FYAKMLNHDY CTKEVFNNNF FKDFRKSMTP 
    REREIIKDFR KCNFQEMFNY FQAESEKRKA ASKEEKLIKK NENEALMKEF GFCMIDGHKE 
    KIGNFRLEPP GLFRGRGEHP KMGMIKRRIQ ASDVSINCGK DSKVPSPPPG SRWKEVRHDN 
    TVTWLASWIE NVQGQVKYIM LNPSSKLKGE KDHIKYETAR RLDKVIDKIR ATYRDEWKSK 
    EMRVRQRAVA LYFIDKLALR AGNEKDEDQA DTVGCCSLRV EHVQLHKELN GKENVVVFDF 
    PGKDSIRYYN EVEVEKRVFK NLELFMEHKK EGDDLFDRLN TQVLNEHLKE LMEGLTAKVF 
    RTYNASKTLQ SQLDLLTDPS ATVPEKLLAY NRANRAVAIL CNHQRSVPKS HEKSMENLKE 
    KIKAKREAIE KCESEYHSRD EKKGKQLERL RDQLKKLELQ ETDRDENKTI ALGTSKLNYL 
    DPRISVAWCK KHDVPIEKIF NKTQRTKFLW AVHMADENYR F

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.