APEH | ENSG00000164062 | NCBI 327

Details for: APEH

Gene ID: 327

Symbol: APEH

Ensembl ID: ENSG00000164062

Description: acylaminoacyl-peptide hydrolase

Associated with

Eukaryotic translation termination
(R-HSA-72764)
Immune system
(R-HSA-168256)
Innate immune system
(R-HSA-168249)
Metabolism of proteins
(R-HSA-392499)
Neutrophil degranulation
(R-HSA-6798695)
Translation
(R-HSA-72766)
Amyloid-beta metabolic process
(GO:0050435)
Cytosol
(GO:0005829)
Extracellular exosome
(GO:0070062)
Extracellular region
(GO:0005576)
Ficolin-1-rich granule lumen
(GO:1904813)
Identical protein binding
(GO:0042802)
Nuclear membrane
(GO:0031965)
Omega peptidase activity
(GO:0008242)
Protein binding
(GO:0005515)
Proteolysis
(GO:0006508)
Rna binding
(GO:0003723)
Serine-type endopeptidase activity
(GO:0004252)
Translational termination
(GO:0006415)

Other Information

Proteins

Acylamino-acid-releasing enzyme

Genular Protein ID: 1703787310

Symbol: ACPH_HUMAN

Name: Acylamino-acid-releasing enzyme

UniProtKB Accession Codes:

P13798 Q9BQ33 Q9P0Y2

Database IDs:

Citations:

PubMed ID: 8724851

Title: The nucleotide sequence of human acylamino acid-releasing enzyme.

PubMed ID: 8724851

DOI: 10.1093/dnares/3.1.31

PubMed ID: 10719179

Title: Identification of oxidized protein hydrolase of human erythrocytes as acylpeptide hydrolase.

PubMed ID: 10719179

DOI: 10.1016/s0167-4838(00)00004-2

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2565880

Title: The DNF15S2 locus at 3p21 is transcribed in normal lung and small cell lung cancer.

PubMed ID: 2565880

DOI: 10.1016/0888-7543(89)90342-x

PubMed ID: 10395453

Title: Structural investigations on human erythrocyte acylpeptide hydrolase by mass spectrometric procedures.

PubMed ID: 10395453

DOI: 10.1023/a:1021047730831

PubMed ID: 1861871

Title: The gene from the short arm of chromosome 3, at D3F15S2, frequently deleted in renal cell carcinoma, encodes acylpeptide hydrolase.

PubMed ID: 1861871

PubMed ID: 2006156

Title: Genetic relationship between acylpeptide hydrolase and acylase, two hydrolytic enzymes with similar binding but different catalytic specificities.

PubMed ID: 2006156

DOI: 10.1073/pnas.88.6.2194

PubMed ID: 1740429

Title: Acylpeptide hydrolase: inhibitors and some active site residues of the human enzyme.

PubMed ID: 1740429

DOI: 10.1016/s0021-9258(19)50598-1

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 8411161

Title: Crystallization and preliminary X-ray studies of human erythrocyte acylpeptide hydrolase.

PubMed ID: 8411161

DOI: 10.1006/jmbi.1993.1531

Sequence Information:

Length: 732
Mass: 81225
Checksum: A2C370516324D851
Sequence:

MERQVLLSEP EEAAALYRGL SRQPALSAAC LGPEVTTQYG GQYRTVHTEW TQRDLERMEN 
IRFCRQYLVF HDGDSVVFAG PAGNSVETRG ELLSRESPSG TMKAVLRKAG GTGPGEEKQF 
LEVWEKNRKL KSFNLSALEK HGPVYEDDCF GCLSWSHSET HLLYVAEKKR PKAESFFQTK 
ALDVSASDDE IARLKKPDQA IKGDQFVFYE DWGENMVSKS IPVLCVLDVE SGNISVLEGV 
PENVSPGQAF WAPGDAGVVF VGWWHEPFRL GIRFCTNRRS ALYYVDLIGG KCELLSDDSL 
AVSSPRLSPD QCRIVYLQYP SLIPHHQCSQ LCLYDWYTKV TSVVVDVVPR QLGENFSGIY 
CSLLPLGCWS ADSQRVVFDS AQRSRQDLFA VDTQVGTVTS LTAGGSGGSW KLLTIDQDLM 
VAQFSTPSLP PTLKVGFLPS AGKEQSVLWV SLEEAEPIPD IHWGIRVLQP PPEQENVQYA 
GLDFEAILLQ PGSPPDKTQV PMVVMPHGGP HSSFVTAWML FPAMLCKMGF AVLLVNYRGS 
TGFGQDSILS LPGNVGHQDV KDVQFAVEQV LQEEHFDASH VALMGGSHGG FISCHLIGQY 
PETYRACVAR NPVINIASML GSTDIPDWCV VEAGFPFSSD CLPDLSVWAE MLDKSPIRYI 
PQVKTPLLLM LGQEDRRVPF KQGMEYYRAL KTRNVPVRLL LYPKSTHALS EVEVESDSFM 
NAVLWLRTHL GS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: APEH

Associated with

Other Information

The nucleotide sequence of human acylamino acid-releasing enzyme. PubMed ID: 8724851

Identification of oxidized protein hydrolase of human erythrocytes as acylpeptide hydrolase. PubMed ID: 10719179

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The DNF15S2 locus at 3p21 is transcribed in normal lung and small cell lung cancer. PubMed ID: 2565880

Structural investigations on human erythrocyte acylpeptide hydrolase by mass spectrometric procedures. PubMed ID: 10395453

The gene from the short arm of chromosome 3, at D3F15S2, frequently deleted in renal cell carcinoma, encodes acylpeptide hydrolase. PubMed ID: 1861871

Genetic relationship between acylpeptide hydrolase and acylase, two hydrolytic enzymes with similar binding but different catalytic specificities. PubMed ID: 2006156

Acylpeptide hydrolase: inhibitors and some active site residues of the human enzyme. PubMed ID: 1740429

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. PubMed ID: 19690332

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Initial characterization of the human central proteome. PubMed ID: 21269460

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. PubMed ID: 21406692

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

Crystallization and preliminary X-ray studies of human erythrocyte acylpeptide hydrolase. PubMed ID: 8411161