Details for: Sh

Gene ID: 32780

Symbol: Sh

Ensembl ID: FBgn0003380

Description: Shaker

Associated with

Other Information

Genular Protein ID: 1377030190

Symbol: KCNAS_DROME

Name: Potassium voltage-gated channel protein Shaker

UniProtKB Accession Codes:

P08510 A4V4Q2 B6IDJ2 M9MSC0 M9NEM4 M9PF21 P08511 P08512 P08513 Q24277 Q24521 Q7KUW5 Q8IQY9 Q8MT41 Q9VWZ5 Q9VWZ9 Q9VX00

Database IDs:

AGR 1 AlphaFoldDB 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DIP 1 DisProt 1 EMBL 21 EMDB 3 EnsemblMetazoa 11 EvolutionaryTrace 1 ExpressionAtlas 1 FlyBase 1 GO 27 Gene3D 2 GeneTree 1 GenomeRNAi 1 GlyCosmos 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MINT 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 5 PIR 4 PRINTS 3 PRO 1 PaxDb 1 Pfam 2 PhylomeDB 1 Proteomes 1 Reactome 2 RefSeq 11 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TCDB 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 2441471

Title: Sequence of a probable potassium channel component encoded at Shaker locus of Drosophila.

PubMed ID: 2441471

DOI: 10.1126/science.2441471

PubMed ID: 16453805

Title: Molecular organization of the maternal effect region of the Shaker complex of Drosophila: characterization of an I(A) channel transcript with homology to vertebrate Na(+) channel.

PubMed ID: 16453805

DOI: 10.1002/j.1460-2075.1987.tb02665.x

PubMed ID: 2456921

Title: Shaker encodes a family of putative potassium channel proteins in the nervous system of Drosophila.

PubMed ID: 2456921

DOI: 10.1002/j.1460-2075.1988.tb02917.x

PubMed ID: 2448635

Title: Multiple potassium-channel components are produced by alternative splicing at the Shaker locus in Drosophila.

PubMed ID: 2448635

DOI: 10.1038/331137a0

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 2440582

Title: Molecular characterization of Shaker, a Drosophila gene that encodes a potassium channel.

PubMed ID: 2440582

DOI: 10.1016/0092-8674(87)90494-6

PubMed ID: 3272175

Title: Multiple products of the Drosophila Shaker gene may contribute to potassium channel diversity.

PubMed ID: 3272175

DOI: 10.1016/0896-6273(88)90192-4

PubMed ID: 2448636

Title: Expression of functional potassium channels from Shaker cDNA in Xenopus oocytes.

PubMed ID: 2448636

DOI: 10.1038/331143a0

PubMed ID: 10934243

Title: A novel leg-shaking Drosophila mutant defective in a voltage-gated K(+)current and hypersensitive to reactive oxygen species.

PubMed ID: 10934243

DOI: 10.1523/jneurosci.20-16-05958.2000

PubMed ID: 12907802

Title: Nervous system targets of RNA editing identified by comparative genomics.

PubMed ID: 12907802

DOI: 10.1126/science.1086763

PubMed ID: 15858564

Title: Reduced sleep in Drosophila Shaker mutants.

PubMed ID: 15858564

DOI: 10.1038/nature03486

PubMed ID: 17893096

Title: Identification of N-glycosylated proteins from the central nervous system of Drosophila melanogaster.

PubMed ID: 17893096

DOI: 10.1093/glycob/cwm097

PubMed ID: 20010822

Title: SLEEPLESS, a Ly-6/neurotoxin family member, regulates the levels, localization and activity of Shaker.

PubMed ID: 20010822

DOI: 10.1038/nn.2454

PubMed ID: 21813698

Title: Drosophila QVR/SSS modulates the activation and C-type inactivation kinetics of Shaker K(+) channels.

PubMed ID: 21813698

DOI: 10.1523/jneurosci.0502-11.2011

PubMed ID: 22292044

Title: Genes involved in sex pheromone discrimination in Drosophila melanogaster and their background-dependent effect.

PubMed ID: 22292044

DOI: 10.1371/journal.pone.0030799

PubMed ID: 24613312

Title: SLEEPLESS is a bifunctional regulator of excitability and cholinergic synaptic transmission.

PubMed ID: 24613312

DOI: 10.1016/j.cub.2014.02.026

PubMed ID: 26828958

Title: Structural Analysis and Deletion Mutagenesis Define Regions of QUIVER/SLEEPLESS that Are Responsible for Interactions with Shaker-Type Potassium Channels and Nicotinic Acetylcholine Receptors.

PubMed ID: 26828958

DOI: 10.1371/journal.pone.0148215

PubMed ID: 12023222

Title: Three-dimensional structure of the S4-S5 segment of the Shaker potassium channel.

PubMed ID: 12023222

DOI: 10.1016/s0006-3495(02)75640-3

Sequence Information:

  • Length: 655
  • Mass: 74193
  • Checksum: 5833E3052C9D19B3
  • Sequence:
    • MAAVAGLYGL GEDRQHRKKQ QQQQQHQKEQ LEQKEEQKKI AERKLQLREQ QLQRNSLDGY 
GSLPKLSSQD EEGGAGHGFG GGPQHFEPIP HDHDFCERVV INVSGLRFET QLRTLNQFPD 
TLLGDPARRL RYFDPLRNEY FFDRSRPSFD AILYYYQSGG RLRRPVNVPL DVFSEEIKFY 
ELGDQAINKF REDEGFIKEE ERPLPDNEKQ RKVWLLFEYP ESSQAARVVA IISVFVILLS 
IVIFCLETLP EFKHYKVFNT TTNGTKIEED EVPDITDPFF LIETLCIIWF TFELTVRFLA 
CPNKLNFCRD VMNVIDIIAI IPYFITLATV VAEEEDTLNL PKAPVSPQDK SSNQAMSLAI 
LRVIRLVRVF RIFKLSRHSK GLQILGRTLK ASMRELGLLI FFLFIGVVLF SSAVYFAEAG 
SENSFFKSIP DAFWWAVVTM TTVGYGDMTP VGVWGKIVGS LCAIAGVLTI ALPVPVIVSN 
FNYFYHRETD QEEMQSQNFN HVTSCPYLPG TLGQHMKKSS LSESSSDMMD LDDGVESTPG 
LTETHPGRSA VAPFLGAQQQ QQQPVASSLS MSIDKQLQHP LQQLTQTQLY QQQQQQQQQQ 
QNGFKQQQQQ TQQQLQQQQS HTINASAAAA TSGSGSSGLT MRHNNALAVS IETDV

Genular Protein ID: 2157602142

Symbol: M9PJQ4_DROME

Name: N/A

UniProtKB Accession Codes:

M9PJQ4

Database IDs:

AGR 1 ARBA 11 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 EMBL 2 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 2 GO 3 Gene3D 1 GeneTree 1 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 Pfam 2 Proteomes 2 RefSeq 1 SAM 2 SMART 2 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 337
  • Mass: 38801
  • Checksum: 094307BE38944A06
  • Sequence:
    • MTMWQSGGMG GHGSQNNPWM KLMGIVHKER RHTENVQSQS GSNERNLNQS LPKLSSQDEE 
GGAGHGFGGG PQHFEPIPHD HDFCERVVIN VSGLRFETQL RTLNQFPDTL LGDPARRLRY 
FDPLRNEYFF DRSRPSFDAI LYYYQSGGRL RRPVNVPLDV FSEEIKFYEL GDQAINKFRE 
DEGFIKEEER PLPDNEKQRK VWLLFEYPES SQAARVVAII SVFVILLSIV IFCLETLPEF 
KHYKVFNTTT NGTKIEEDEV PDITDPFFLI ETLCIIWFTF ELTVRFLACP NKLNFCRDVM 
NVIDIIAIIP YFITLATVVA EEEDTLNLPK APVSPQV

Genular Protein ID: 3981152489

Symbol: A0A0S0X7Z4_DROME

Name: N/A

UniProtKB Accession Codes:

A0A0S0X7Z4

Database IDs:

AGR 1 ARBA 12 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 EMBL 2 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 2 GO 3 Gene3D 2 GeneTree 1 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 3 Pfam 2 Proteomes 2 RefSeq 1 SAM 2 SMART 2 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 655
  • Mass: 74193
  • Checksum: 7ACE6E3BC0CD4198
  • Sequence:
    • MAAVAGLYGL GEDRQHRKKQ QQQQQHQKEQ LEQKEEQKKI AERKLQLREQ QLQRNSLDGY 
GSLPKLSSQD EEGGAGHGFG GGPQHFEPIP HDHDFCERVV INVSGLRFET QLRTLNQFPD 
TLLGDPARRL RYFDPLRNEY FFDRSRPSFD AILYYYQSGG RLRRPVNVPL DVFSEEIKFY 
ELGDQAINKF REDEGFIKEE ERPLPDNEKQ RKVWLLFEYP ESSQAARVVA IISVFVILLS 
IVIFCLETLP EFKHYKVFNT TTNGTKIEED EVPDITDPFF LIETLCIIWF TFELTVRFLA 
CPNKLNFCRD VMNVIDIIAI IPYFITLATV VAEEEDTLNL PKAPVSPQDK SSNQAMSLAI 
LRVIRLVRVF RIFKLSRHSK GLQILGRTLK ASMRELGLLI FFLFIGVVLF SSAVYFAEAG 
SDSSFFKSIP DGFWWAVVTM TTVGYGDMRP VGVWGKIVGS LCAIAGVLTI ALPVPVIVSN 
FNYFYHRETD QEEMQSQNFN HVTSCPYLPG TLGQHMKKSS LSESSSDMMD LDDGVESTPG 
LTETHPGRSA VAPFLGAQQQ QQQPVASSLS MSIDKQLQHP LQQLTQTQLY QQQQQQQQQQ 
QNGFKQQQQQ TQQQLQQQQS HTINASAAAA TSGSGSSGLT MRHNNALAVS IETDV

Genular Protein ID: 2343261318

Symbol: M9PHG6_DROME

Name: N/A

UniProtKB Accession Codes:

M9PHG6

Database IDs:

AGR 1 ARBA 12 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 EMBL 2 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 2 GO 3 Gene3D 2 GeneTree 1 HOGENOM 1 InterPro 8 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 4 Pfam 2 Proteomes 2 RefSeq 1 SAM 2 SMART 2 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 604
  • Mass: 68552
  • Checksum: 408DC18315FF7619
  • Sequence:
    • MRTTCSSSTI SRIDFIERWG LTPVLRPRQE QPLSGENLSN ASPPLLCDRS LPKLSSQDEE 
GGAGHGFGGG PQHFEPIPHD HDFCERVVIN VSGLRFETQL RTLNQFPDTL LGDPARRLRY 
FDPLRNEYFF DRSRPSFDAI LYYYQSGGRL RRPVNVPLDV FSEEIKFYEL GDQAINKFRE 
DEGFIKEEER PLPDNEKQRK VWLLFEYPES SQAARVVAII SVFVILLSIV IFCLETLPEF 
KHYKVFNTTT NGTKIEEDEV PDITDPFFLI ETLCIIWFTF ELTVRFLACP NKLNFCRDVM 
NVIDIIAIIP YFITLATVVA EEEDTLNLPK APVSPQDKSS NQAMSLAILR VIRLVRVFRI 
FKLSRHSKGL QILGRTLKAS MRELGLLIFF LFIGVVLFSS AVYFAEAGSE NSFFKSIPDA 
FWWAVVTMTT VGYGDMTPVG FWGKIVGSLC VIAGVLTIAL PVPVIVSNFN YFYHRETDQE 
EMQSQNFNHV TSCSYLPGAL GQHLKKSSLS ESSSDIMDLD DGIDATTPGL TDHTGRHMVP 
FLRTQQSFEK QQLQLQLQLQ QQSQSPHGQQ MTQQQQLGQN GLRSTNSLQL RHNNAMAVSI 
ETDV

Genular Protein ID: 4189644482

Symbol: E1JJQ5_DROME

Name: N/A

UniProtKB Accession Codes:

E1JJQ5

Database IDs:

AGR 1 ARBA 11 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 EMBL 2 EnsemblMetazoa 2 ExpressionAtlas 1 FlyBase 2 GO 3 Gene3D 1 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 Pfam 2 Proteomes 2 RefSeq 2 SAM 2 SMART 2 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 304
  • Mass: 34946
  • Checksum: 05898ADD605604B5
  • Sequence:
    • MAHITTTHGS LSQATRSLPK LSSQDEEGGA GHGFGGGPQH FEPIPHDHDF CERVVINVSG 
LRFETQLRTL NQFPDTLLGD PARRLRYFDP LRNEYFFDRS RPSFDAILYY YQSGGRLRRP 
VNVPLDVFSE EIKFYELGDQ AINKFREDEG FIKEEERPLP DNEKQRKVWL LFEYPESSQA 
ARVVAIISVF VILLSIVIFC LETLPEFKHY KVFNTTTNGT KIEEDEVPDI TDPFFLIETL 
CIIWFTFELT VRFLACPNKL NFCRDVMNVI DIIAIIPYFI TLATVVAEEE DTLNLPKAPV 
SPQV

Genular Protein ID: 1786823792

Symbol: M9NGK2_DROME

Name: N/A

UniProtKB Accession Codes:

M9NGK2

Database IDs:

AGR 1 ARBA 11 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 EMBL 2 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 2 GO 3 Gene3D 1 GeneTree 1 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 Pfam 2 Proteomes 2 RefSeq 1 SAM 2 SMART 2 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 297
  • Mass: 34153
  • Checksum: 13280F1954E9F546
  • Sequence:
    • MQMILVAGGS LPKLSSQDEE GGAGHGFGGG PQHFEPIPHD HDFCERVVIN VSGLRFETQL 
RTLNQFPDTL LGDPARRLRY FDPLRNEYFF DRSRPSFDAI LYYYQSGGRL RRPVNVPLDV 
FSEEIKFYEL GDQAINKFRE DEGFIKEEER PLPDNEKQRK VWLLFEYPES SQAARVVAII 
SVFVILLSIV IFCLETLPEF KHYKVFNTTT NGTKIEEDEV PDITDPFFLI ETLCIIWFTF 
ELTVRFLACP NKLNFCRDVM NVIDIIAIIP YFITLATVVA EEEDTLNLPK APVSPQV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.