Details for: Frq2

Gene ID: 32799

Symbol: Frq2

Ensembl ID: FBgn0083228

Description: Frequenin 2

Associated with

Other Information

Genular Protein ID: 3438166062

Symbol: FRQ2_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 17970740

Title: Chronic and acute alterations in the functional levels of Frequenins 1 and 2 reveal their roles in synaptic transmission and axon terminal morphology.

PubMed ID: 17970740

DOI: 10.1111/j.1460-9568.2007.05877.x

PubMed ID: 24699756

Title: Frq2 from Drosophila melanogaster: cloning, expression, purification, crystallization and preliminary X-ray analysis.

PubMed ID: 24699756

DOI: 10.1107/s2053230x14005408

PubMed ID: 25074811

Title: The guanine-exchange factor Ric8a binds to the Ca sensor NCS-1 to regulate synapse number and neurotransmitter release.

PubMed ID: 25074811

DOI: 10.1242/jcs.152603

PubMed ID: 28119500

Title: Interference of the complex between NCS-1 and Ric8a with phenothiazines regulates synaptic function and is an approach for fragile X syndrome.

PubMed ID: 28119500

DOI: 10.1073/pnas.1611089114

PubMed ID: 29966094

Title: Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function Regulators.

PubMed ID: 29966094

DOI: 10.1021/acs.jmedchem.8b00088

Sequence Information:

  • Length: 187
  • Mass: 21875
  • Checksum: F12AADF07BB8249D
  • Sequence:
  • MGKKNSKLKQ DTIDRLTTDT YFTEKEIRQW HKGFLKDCPN GLLTEQGFIK IYKQFFPDGD 
    PSKFASLVFR VFDENNDGAI EFEEFIRALS ITSRGNLDEK LHWAFRLYDV DNDGYITREE 
    MYNIVDAIYQ MVGQQPQTED ENTPQKRVDK IFDQMDKNHD DRLTLEEFRE GSKADPRIVQ 
    ALSLGGD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.