Mer | FBgn0086384 | NCBI 32979

Details for: Mer

Gene ID: 32979

Symbol: Mer

Ensembl ID: FBgn0086384

Description: Merlin

Associated with

Fcgamma receptor (fcgr) dependent phagocytosis
(R-DME-2029480)
Immune system
(R-DME-168256)
Innate immune system
(R-DME-168249)
Regulation of actin dynamics for phagocytic cup formation
(R-DME-2029482)
Rho gtpase effectors
(R-DME-195258)
Rho gtpases activate paks
(R-DME-5627123)
Signaling by rho gtpases
(R-DME-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-DME-9716542)
Signal transduction
(R-DME-162582)
Actin binding
(GO:0003779)
Adherens junction
(GO:0005912)
Apical part of cell
(GO:0045177)
Apical plasma membrane
(GO:0016324)
Apicomedial cortex
(GO:0106037)
Axis specification
(GO:0009798)
Cell-cell junction
(GO:0005911)
Cell-cell signaling
(GO:0007267)
Cell cortex
(GO:0005938)
Compound eye morphogenesis
(GO:0001745)
Compound eye photoreceptor cell differentiation
(GO:0001751)
Cytoplasm
(GO:0005737)
Cytoplasmic side of apical plasma membrane
(GO:0098592)
Cytoskeleton
(GO:0005856)
Endocytic recycling
(GO:0032456)
Endocytosis
(GO:0006897)
Epithelial structure maintenance
(GO:0010669)
Filopodium
(GO:0030175)
Hippo signaling
(GO:0035329)
Integrin binding
(GO:0005178)
Kibra-ex-mer complex
(GO:0036375)
Male meiosis cytokinesis
(GO:0007112)
Meiotic chromosome separation
(GO:0051307)
Membrane
(GO:0016020)
Nebenkern
(GO:0016006)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of glial cell proliferation
(GO:0060253)
Negative regulation of organ growth
(GO:0046621)
Plasma membrane
(GO:0005886)
Pole plasm mrna localization
(GO:0019094)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of cell-cell adhesion
(GO:0022409)
Positive regulation of early endosome to late endosome transport
(GO:2000643)
Positive regulation of hippo signaling
(GO:0035332)
Positive regulation of protein localization to early endosome
(GO:1902966)
Positive regulation of protein phosphorylation
(GO:0001934)
Protein binding
(GO:0005515)
Protein localization to plasma membrane
(GO:0072659)
R8 cell development
(GO:0045463)
R8 cell fate specification
(GO:0045464)
Regulation of cell differentiation
(GO:0045595)
Regulation of cell growth
(GO:0001558)
Regulation of cell population proliferation
(GO:0042127)
Regulation of cell shape
(GO:0008360)
Regulation of compound eye retinal cell programmed cell death
(GO:0046669)
Regulation of gliogenesis
(GO:0014013)
Regulation of hippo signaling
(GO:0035330)
Regulation of organelle assembly
(GO:1902115)
Regulation of signal transduction
(GO:0009966)
Spermatogenesis
(GO:0007283)
Sperm individualization
(GO:0007291)
Subapical part of cell
(GO:0120219)

Other Information

Proteins

Moesin/ezrin/radixin homolog 2

Genular Protein ID: 2341211103

Symbol: MERH_DROME

Name: Moesin/ezrin/radixin homolog 2

UniProtKB Accession Codes:

Q24564 Q24054 Q8SWY3

Database IDs:

Citations:

PubMed ID: 8666669

Title: Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin.

PubMed ID: 8666669

DOI: 10.1083/jcb.133.4.843

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 20159598

Title: Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded.

PubMed ID: 20159598

DOI: 10.1016/j.devcel.2009.12.012

PubMed ID: 26954546

Title: Drosophila Schip1 links Expanded and Tao-1 to regulate hippo signaling.

PubMed ID: 26954546

DOI: 10.1016/j.devcel.2016.02.004

Sequence Information:

Length: 635
Mass: 74492
Checksum: 940D6B8A0D160A3F
Sequence:

MSPFGSKKNR SLSVRVSTFD SELEFKLEPR ASGQDLFDLV CRTIGLRESW YFGLQYVDTR 
SNVSWLKMEK RVRDQRVELH ASNNVYVFSF YAKFFPENVS EELIQEITQH LFFLQVKQSI 
LSMDIYCRPE ASVLLASYAV HVQYGPYDYE TYKDGMLAGG ELLPKGVTDQ YQMTPEMWEE 
RIKTWYMDHE PMTRDEVEME YLKIAQDLDM YGVNYFPITN KNKTKLWLGV TSVGLNIYDE 
RDKLTPKTTF QWNEIRHVSF DDKKFTIRLV DAKVSNFIFY SQDLHINKMI LDLCKGNHDL 
YMRRRKPDTM EIQQMKAQAK EEKQRRQIER KKFIREKKLR EKAEHERYEL EKSMEHLQNE 
MRMANDALRR SEETKELYFE KSRVNEEQMQ LTECKANHFK TEMDRLRERQ MKIEREKHDL 
EKKIRDADFY VHQLTVENDK REAETEKLRK ELICAKMAER EATARLLEFL NSGRKSSTDS 
LLTASSVSHA ANTASSMAAI STPSLITSSS TNDLETAGGA ELTTHSSHYL VQGDNSSGIS 
DDFEPKEFIL TDNEMEQITN EMERNHLDYL RNSKQVQSQL QTLRSEIAPH KIEENQSNLD 
ILSEAQIKAG ENKYSTLKKL KSGSTKARVA FFEEL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Mer

Associated with

Other Information

Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin. PubMed ID: 8666669

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila full-length cDNA resource. PubMed ID: 12537569

Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded. PubMed ID: 20159598