Associated with
Other Information
Genular Protein ID: 379722399
Symbol: ZELDA_DROME
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10731132
Title: The genome sequence of Drosophila melanogaster.
PubMed ID: 10731132
PubMed ID: 12537572
Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.
PubMed ID: 12537572
PubMed ID: 16525017
Title: Mutations of the Drosophila zinc finger-encoding gene vielfaeltig impair mitotic cell divisions and cause improper chromosome segregation.
PubMed ID: 16525017
PubMed ID: 18931655
Title: The zinc-finger protein Zelda is a key activator of the early zygotic genome in Drosophila.
PubMed ID: 18931655
DOI: 10.1038/nature07388
PubMed ID: 20599892
Title: Grainyhead and Zelda compete for binding to the promoters of the earliest-expressed Drosophila genes.
PubMed ID: 20599892
PubMed ID: 22028662
Title: Zelda binding in the early Drosophila melanogaster embryo marks regions subsequently activated at the maternal-to-zygotic transition.
PubMed ID: 22028662
PubMed ID: 22028675
Title: Temporal coordination of gene networks by Zelda in the early Drosophila embryo.
PubMed ID: 22028675
PubMed ID: 23891688
Title: The embryonic transcription factor Zelda of Drosophila melanogaster is also expressed in larvae and may regulate developmentally important genes.
PubMed ID: 23891688
PubMed ID: 24909324
Title: Zelda potentiates morphogen activity by increasing chromatin accessibility.
PubMed ID: 24909324
PubMed ID: 24764079
Title: Co-activation of microRNAs by Zelda is essential for early Drosophila development.
PubMed ID: 24764079
DOI: 10.1242/dev.108118
PubMed ID: 24637116
Title: Impacts of the ubiquitous factor Zelda on Bicoid-dependent DNA binding and transcription in Drosophila.
PubMed ID: 24637116
PubMed ID: 26335633
Title: Zelda overcomes the high intrinsic nucleosome barrier at enhancers during Drosophila zygotic genome activation.
PubMed ID: 26335633
PubMed ID: 26335634
Title: Zelda is differentially required for chromatin accessibility, transcription factor binding, and gene expression in the early Drosophila embryo.
PubMed ID: 26335634
PubMed ID: 25538246
Title: Transcriptional activation is a conserved feature of the early embryonic factor Zelda that requires a cluster of four zinc fingers for DNA binding and a low-complexity activation domain.
PubMed ID: 25538246
PubMed ID: 29261646
Title: A conserved maternal-specific repressive domain in Zelda revealed by Cas9-mediated mutagenesis in Drosophila melanogaster.
PubMed ID: 29261646
PubMed ID: 30518940
Title: Temporal control of gene expression by the pioneer factor Zelda through transient interactions in hubs.
PubMed ID: 30518940
PubMed ID: 30982648
Title: The Drosophila pioneer factor Zelda modulates the nuclear microenvironment of a Dorsal target enhancer to potentiate transcriptional output.
PubMed ID: 30982648
PubMed ID: 30797686
Title: Continued activity of the pioneer factor Zelda is required to drive zygotic genome activation.
PubMed ID: 30797686
PubMed ID: 34342574
Title: CLAMP and Zelda function together to promote Drosophila zygotic genome activation.
PubMed ID: 34342574
DOI: 10.7554/elife.69937
PubMed ID: 34887421
Title: Cell-type-specific chromatin occupancy by the pioneer factor Zelda drives key developmental transitions in Drosophila.
PubMed ID: 34887421
PubMed ID: 35363606
Title: Synthetic reconstruction of the hunchback promoter specifies the role of Bicoid, Zelda and Hunchback in the dynamics of its transcription.
PubMed ID: 35363606
DOI: 10.7554/elife.74509
PubMed ID: 37557175
Title: Chromatin accessibility in the Drosophila embryo is determined by transcription factor pioneering and enhancer activation.
PubMed ID: 37557175
Sequence Information:
- Length: 1596
- Mass: 170323
- Checksum: 30C50B924B02CC8D
- Sequence:
MTSIKTEMPP LHAAEALASS SATDSGGGGA GGGGGGGGGG SGGPGAGGTG GVGSAPATPN ATISAAADSS DNQPGTPQPT QQQQSTQQQL QQPQSQQQQQ QAMGGGDPQQ QQQQQQVTGI THQPYATHHM YSASGGQQQQ QQQIYGGLYG GDMQQQQGYA SSYINSYEQF YQQQQQQQQG TDYAFGTVGV DYGKSAGVRY HPYLQTPTSG LGGIPTASSA QEEAGSAPSA VSTTTAVAMS PRVVSSSSPT STSSHLQLGS SSGQTPGSPG GAAGSAGCKL QCKKCGILTT NESELQEHIA NVHGESPYGS SGYASSPYIK EEMPTPQPPG VGSATANPGE LLDLDSQKMV YHQQLLQQQQ QQHDVVAGLP LGALPDPLHS MQSMQQRALH SWEQQPQQTV ASVEGLPPYM QQGLGVGLGV GVDKSPYYSP KQSPYHQSTG VGGATLIKQE YGGHGLIKSE YPDSQHYVDK SFDPTAGGAG GAELCASVAT SPAEFPSTTT GGPGQEGAAG AAPGGGYRGF EPPSSSSVLP ANSLTAKAAT WKSNEARRPK TYNCTACNKW FTSSGHLKRH YNTTLHKNAV KSSGQPDPAT LPISAHHHPA RDPVTKPSRR GNAAAAAAAA AAAASASGQG QQQQPPIPPP PANVPPPEPP RSPPDYGGGG GLGVGAMGGA AMSQYSASPS PTQQQQHHLN HHQQQANGYA NGTANGYGYM QQQVQSTTNA SPQHASNNNS NNQQQQQQQQ QHHQQQMPQH HNSVLNGHPN GLAGPSAPHN NNTTQMPSSQ MRGLLNETTT TPPPTTTTRA PQITTTATTT TTAATTVAIK SEQMEDSNHT HTHTHTHPNH SHSQDRSHSS SSSSSMATEE AEEQELRDQE QADDHLHQHQ QASQQYLLSA RHYHSSTPNT LSSSNTNPST PSSNSPHTIY RQEQQGTDFS RTTPPPQPLP PMGMLPPMAM DYNMLALDMP MPMPTLMHSN MLQCSSTSTT PLATTITTSM PDTMQPPQQQ LVHHYQAVLH PLHQQLGEQH QRQEADHHQQ QRELHQLDQQ QQQQQALILA DSLPHSSSSP TSSSPPPTMP MPLTTITAPQ LLPLQPPPPH ITSTMPMPPT MHMPIMPPPP QCYQQLQPLD PTMSYHTIIG SGPEAHTGTA GGGYSNQITT SDGQILQLMP TSLFAPYAPL SPYSVAAQRS PQEGDLPPVH TLTTALHAHQ QGGQQEAQTP TLTVLSTPYS PTVSSSRATP ALEMDMATLM QHHQDYEMEQ YQMQHQQLDQ MQQHQQQLDH QQQQQILADQ TQTMAQQPLA KKRRGGNATP STTKRRRNSS VGSTSPHSTT LPSGRIKCLE CDKEFTKNCY LTQHNKSFHS GEYPFRCQKC GKRFQSEDVY TTHLGRHRTQ DKPHKCELCP KQFHHKTDLR RHVEAIHTGL KQHMCDICEK GFCRKDHLRK HLETHNRPRV VGKKSAAAAA AAAAAAAVTA TAGLGGAPAA GSIKAAFARS LTVTAVSSEP GAGVAIPSAP ATATCAPVSV SASALVQAVN PSLTSGLSLK RHIDDVAVDD DSLLEEDEDE MEMEMEMDML EEEDEEEEEL GDHHMIIKSE YVQEEFQMIE KSIELY
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.