Details for: ush

Gene ID: 33225

Symbol: ush

Ensembl ID: FBgn0003963

Description: u-shaped

Associated with

  • Factors involved in megakaryocyte development and platelet production
    (R-DME-983231)
  • Gene expression (transcription)
    (R-DME-74160)
  • Generic transcription pathway
    (R-DME-212436)
  • Hemostasis
    (R-DME-109582)
  • Rna polymerase ii transcription
    (R-DME-73857)
  • Runx1 regulates genes involved in megakaryocyte differentiation and platelet function
    (R-DME-8936459)
  • Transcriptional regulation by runx1
    (R-DME-8878171)
  • Amnioserosa maintenance
    (GO:0046665)
  • Cell differentiation
    (GO:0030154)
  • Chaeta development
    (GO:0022416)
  • Compound eye development
    (GO:0048749)
  • Dna-binding transcription repressor activity
    (GO:0001217)
  • Germ-band shortening
    (GO:0007390)
  • Heart development
    (GO:0007507)
  • Larval lymph gland hemopoiesis
    (GO:0035167)
  • Lymph gland crystal cell differentiation
    (GO:0035170)
  • Lymph gland development
    (GO:0048542)
  • Lymph gland plasmatocyte differentiation
    (GO:0035169)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of hemocyte differentiation
    (GO:0045611)
  • Negative regulation of insulin receptor signaling pathway
    (GO:0046627)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleus
    (GO:0005634)
  • Positive regulation of antibacterial peptide biosynthetic process
    (GO:0006963)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii-specific dna-binding transcription factor binding
    (GO:0061629)

Other Information

Genular Protein ID: 38669370

Symbol: USH_DROME

Name: Zinc finger protein ush

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9367989

Title: U-shaped encodes a zinc finger protein that regulates the proneural genes achaete and scute during the formation of bristles in Drosophila.

PubMed ID: 9367989

DOI: 10.1101/gad.11.22.3083

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 9367990

Title: Transcriptional activity of pannier is regulated negatively by heterodimerization of the GATA DNA-binding domain with a cofactor encoded by the u-shaped gene of Drosophila.

PubMed ID: 9367990

DOI: 10.1101/gad.11.22.3096

PubMed ID: 10329627

Title: Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers.

PubMed ID: 10329627

DOI: 10.1093/emboj/18.10.2812

PubMed ID: 10861002

Title: The multitype zinc-finger protein U-shaped functions in heart cell specification in the Drosophila embryo.

PubMed ID: 10861002

DOI: 10.1073/pnas.97.13.7348

PubMed ID: 11404479

Title: The Friend of GATA proteins U-shaped, FOG-1, and FOG-2 function as negative regulators of blood, heart, and eye development in Drosophila.

PubMed ID: 11404479

DOI: 10.1073/pnas.131215798

PubMed ID: 12374748

Title: Two isoforms of Serpent containing either one or two GATA zinc fingers have different roles in Drosophila haematopoiesis.

PubMed ID: 12374748

DOI: 10.1093/emboj/cdf545

PubMed ID: 12782269

Title: Prepattern genes and signaling molecules regulate stripe expression to specify Drosophila flight muscle attachment sites.

PubMed ID: 12782269

DOI: 10.1016/s0925-4773(03)00042-x

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

PubMed ID: 11080638

Title: Solution structures of two CCHC zinc fingers from the FOG family protein U-shaped that mediate protein-protein interactions.

PubMed ID: 11080638

DOI: 10.1016/s0969-2126(00)00527-x

PubMed ID: 12110675

Title: Characterization of the conserved interaction between GATA and FOG family proteins.

PubMed ID: 12110675

DOI: 10.1074/jbc.m204663200

Sequence Information:

  • Length: 1191
  • Mass: 124533
  • Checksum: 77A9D990767FE6ED
  • Sequence:
  • MLSSNTRGDC SDTAEEMTVD SRDSKDLSAQ DIGEQKQQQM EDQLEDQLND SRDPQNNNNN 
    IDDDADEDAE FEEPEKANPQ QDQDLGETEM EQEHDLQQED LQQELPANSP STPPRSPSSP 
    QLIPKLEQPA TPPSEPEASP CPSPSPCPTP KYPKVRLNAL LASDPALKPD AKELTLPDSR 
    LLAPPPLVKP DTQAQPEVAE PLLKPARFMC LPCGIAFSSP STLEAHQAYY CSHRIKDTDE 
    AGSDKSGAGG SGATAGDAAG LTGGSTEPPA KMARTGKQYG CTQCSYSADK KVSLNRHMRM 
    HQTSPAAPTL AGLPSLLQNG IAPPGVTPNP MEDSSSQQTD RYCSHCDIRF NNIKTYRAHK 
    QHYCSSRRPE GQLTPKPDAS PGAGSGPGSA GGSIGVSAQA ATPGKLSPQA RNKTPTPAMV 
    AVAAAAAAAA ASLQATPHSH PPFLALPTHP IIIVPCSLIR AASFIPGPLP TPNSGIVNPE 
    TTCFTVDNGT IKPLATALVG ATLEPERPSA PSSAAEATEA KSSPPEPKRK EAGLTRESAP 
    LDLSLRRSPI TLNSLSLRQR QLRNALLDVE EVLLAGVGTG KENVETPRGG GSVTPEQIVC 
    APSLPSSPSM SPSPKRRAIS PRSSGAGSAS SMSPPGLNVA VPHLLDMRSM LPADFGLSES 
    LLAKTNPELA LKLAAAAAAA AVAGSSGAAA FPPASLPAQT SSGNPGSGGS AGGAQQPQIY 
    VKKGVSKCME CNIVFCKYEN YLAHKQHYCS ARSQEGASEV DVKSAVSPSI AGAGGLGAGA 
    AEAASSVETT PVAYQQLICA ACGIKYTSLD NLRAHQNYYC PKGGAVAAPA ATPTDPGQLG 
    MPKEKCGKCK TLHEIGLPCP PPVANPLAAP TVNPQPATNS LNKCPVCGVV SPTAALAKKH 
    MEMHGTVKAY RCSICQYKGN TLRGMRTHIR THFDKKTSDV NEELYMTCIF EEDASALSQE 
    LVTPTGASTT TGHDSMDHPS QMFNCDYCNY VSTYKGNVLR HMKLMHPHVA INSPSISPDT 
    RDQDVTSNPT TNQHSNSDVS NGEAPSFHIK SEPLDPPPTV NLVHENNNSP IATPHIKAEP 
    IEVGADAAPG GLVPPMTSPL GNSSSVAAAA AAAAEVMKKY CSTCDISFNY VKTYLAHKQF 
    YCKNKPIRPE ASDSPSPNHL GGGVAVGLGI GGLVGGHGQQ KNKENLQEAA I

Genular Protein ID: 2718405155

Symbol: M9PDU3_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 1175
  • Mass: 122835
  • Checksum: 4DF66880948DBB6C
  • Sequence:
  • MTVDSRDSKD LSAQDIGEQK QQQMEDQLED QLNDSRDPQN NNNNIDDDAD EDAEFEEPEK 
    ANPQQDQDLG ETEMEQEHDL QQEDLQQELP ANSPSTPPRS PSSPQLIPKL EQPATPPSEP 
    EASPCPSPSP CPTPKYPKVR LNALLASDPA LKPDAKELTL PDSRLLAPPP LVKPDTQAQP 
    EVAEPLLKPA RFMCLPCGIA FSSPSTLEAH QAYYCSHRIK DTDEAGSDKS GAGGSGATAG 
    DAAGLTGGST EPPAKMARTG KQYGCTQCSY SADKKVSLNR HMRMHQTSPA APTLAGLPSL 
    LQNGIAPPGV TPNPMEDSSS QQTDRYCSHC DIRFNNIKTY RAHKQHYCSS RRPEGQLTPK 
    PDASPGAGSG PGSAGGSIGV SAQAATPGKL SPQARNKTPT PAMVAVAAAA AAAAASLQAT 
    PHSHPPFLAL PTHPIIIVPC SLIRAASFIP GPLPTPNSGI VNPETTCFTV DNGTIKPLAT 
    ALVGATLEPE RPSAPSSAAE ATEAKSSPPE PKRKEAGLTR ESAPLDLSLR RSPITLNSLS 
    LRQRQLRNAL LDVEEVLLAG VGTGKENVET PRGGGSVTPE QIVCAPSLPS SPSMSPSPKR 
    RAISPRSSGA GSASSMSPPG LNVAVPHLLD MRSMLPADFG LSESLLAKTN PELALKLAAA 
    AAAAAVAGSS GAAAFPPASL PAQTSSGNPG SGGSAGGAQQ PQIYVKKGVS KCMECNIVFC 
    KYENYLAHKQ HYCSARSQEG ASEVDVKSAV SPSIAGAGGL GAGAAEAASS VETTPVAYQQ 
    LICAACGIKY TSLDNLRAHQ NYYCPKGGAV AAPAATPTDP GQLGMPKEKC GKCKTLHEIG 
    LPCPPPVANP LAAPTVNPQP ATNSLNKCPV CGVVSPTAAL AKKHMEMHGT VKAYRCSICQ 
    YKGNTLRGMR THIRTHFDKK TSDVNEELYM TCIFEEDASA LSQELVTPTG ASTTTGHDSM 
    DHPSQMFNCD YCNYVSTYKG NVLRHMKLMH PHVAINSPSI SPDTRDQDVT SNPTTNQHSN 
    SDVSNGEAPS FHIKSEPLDP PPTVNLVHEN NNSPIATPHI KAEPIEVGAD AAPGGLVPPM 
    TSPLGNSSSV AAAAAAAAEV MKKYCSTCDI SFNYVKTYLA HKQFYCKNKP IRPEASDSPS 
    PNHLGGGVAV GLGIGGLVGG HGQQKNKENL QEAAI

Genular Protein ID: 16759236

Symbol: M9PC12_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

PubMed ID: 26109357

Title: Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.

PubMed ID: 26109357

DOI: .1534/g3.115.018929

PubMed ID: 26109356

Title: Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.

PubMed ID: 26109356

DOI: .1534/g3.115.018937

PubMed ID: 25589440

Title: The Release 6 reference sequence of the Drosophila melanogaster genome.

PubMed ID: 25589440

Sequence Information:

  • Length: 1198
  • Mass: 125409
  • Checksum: 280249B07FB4BD27
  • Sequence:
  • MSRRKQSNPK PLNKGDCSDT AEEMTVDSRD SKDLSAQDIG EQKQQQMEDQ LEDQLNDSRD 
    PQNNNNNIDD DADEDAEFEE PEKANPQQDQ DLGETEMEQE HDLQQEDLQQ ELPANSPSTP 
    PRSPSSPQLI PKLEQPATPP SEPEASPCPS PSPCPTPKYP KVRLNALLAS DPALKPDAKE 
    LTLPDSRLLA PPPLVKPDTQ AQPEVAEPLL KPARFMCLPC GIAFSSPSTL EAHQAYYCSH 
    RIKDTDEAGS DKSGAGGSGA TAGDAAGLTG GSTEPPAKMA RTGKQYGCTQ CSYSADKKVS 
    LNRHMRMHQT SPAAPTLAGL PSLLQNGIAP PGVTPNPMED SSSQQTDRYC SHCDIRFNNI 
    KTYRAHKQHY CSSRRPEGQL TPKPDASPGA GSGPGSAGGS IGVSAQAATP GKLSPQARNK 
    TPTPAMVAVA AAAAAAAASL QATPHSHPPF LALPTHPIII VPCSLIRAAS FIPGPLPTPN 
    SGIVNPETTC FTVDNGTIKP LATALVGATL EPERPSAPSS AAEATEAKSS PPEPKRKEAG 
    LTRESAPLDL SLRRSPITLN SLSLRQRQLR NALLDVEEVL LAGVGTGKEN VETPRGGGSV 
    TPEQIVCAPS LPSSPSMSPS PKRRAISPRS SGAGSASSMS PPGLNVAVPH LLDMRSMLPA 
    DFGLSESLLA KTNPELALKL AAAAAAAAVA GSSGAAAFPP ASLPAQTSSG NPGSGGSAGG 
    AQQPQIYVKK GVSKCMECNI VFCKYENYLA HKQHYCSARS QEGASEVDVK SAVSPSIAGA 
    GGLGAGAAEA ASSVETTPVA YQQLICAACG IKYTSLDNLR AHQNYYCPKG GAVAAPAATP 
    TDPGQLGMPK EKCGKCKTLH EIGLPCPPPV ANPLAAPTVN PQPATNSLNK CPVCGVVSPT 
    AALAKKHMEM HGTVKAYRCS ICQYKGNTLR GMRTHIRTHF DKKTSDVNEE LYMTCIFEED 
    ASALSQELVT PTGASTTTGH DSMDHPSQMF NCDYCNYVST YKGNVLRHMK LMHPHVAINS 
    PSISPDTRDQ DVTSNPTTNQ HSNSDVSNGE APSFHIKSEP LDPPPTVNLV HENNNSPIAT 
    PHIKAEPIEV GADAAPGGLV PPMTSPLGNS SSVAAAAAAA AEVMKKYCST CDISFNYVKT 
    YLAHKQFYCK NKPIRPEASD SPSPNHLGGG VAVGLGIGGL VGGHGQQKNK ENLQEAAI

Genular Protein ID: 47826910

Symbol: M9PBN1_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 1212
  • Mass: 127291
  • Checksum: 90885D39783F733A
  • Sequence:
  • MLSSNTRGDC SDTAEEMTVD SRDSKDLSAQ DIGEQKQQQM EDQLEDQLND SRDPQNNNNN 
    IDDDADEDAE FEEPEKANPQ QDQDLGETEM EQEHDLQQED LQQELPANSP STPPRSPSSP 
    QLIPKLEQPA TPPSEPEASP CPSPSPCPTP KYPKVRLNAL LASDPALKPD AKELTLPDSR 
    LLAPPPLVKP DTQAQPEVAE PLLKPARFMC LPCGIAFSSP STLEAHQAYY CSHRIKDTDE 
    AGSDKSGAGG SGATAGDAAG LTGGSTEPPA KMARTGKQYG CTQCSYSADK KVSLNRHMRM 
    HQTSPAAPTL AGLPSLLQNG IAPPGVTPNP MEDSSSQQTD RYCSHCDIRF NNIKTYRAHK 
    QHYCSSRRPE GQLTPKPDAS PGAGSGPGSA GGSIGVSAQA ATPGKLSPQA RNKTPTPAMV 
    AVAAAAAAAA ASLQATPHSH PPFLALPTHP IIIVPCSLIR AASFIPGPLP TPNSGIVNPE 
    TTCFTVDNGT IKPLATALVG ATLEPERPSA PSSAAEATEA KSSPPEPKRK EAGLTRESAP 
    LDLSLRRSPI TLNSLSLRQR QLRNALLDVE EVLLAGVGTG KENVETPRGG GSVTPEQIVC 
    APSLPSSPSM SPSPKRRAIS PRSSGAGSAS SMSPPGLNVA VPHLLDMRSM LPADFGLSES 
    LLAKTNPELA LKLAAAAAAA AVAGSSGAAA FPPASLPAQT SSGNPGSGGS AGGAQQPQIY 
    VKKGVSKCME CNIVFCKYEN YLAHKQHYCS ARSQEGASEV DVKSAVSPSI AGAGGLGAGA 
    AEAASSVETT PVAYQQLICA ACGIKYTSLD NLRAHQNYYC PKGGAVAAPA ATPTDPGQLG 
    MPKEKCGKCK TLHEIGLPCP PPVANPLAAP TVNPQPATNS LNKCPVCGVV SPTAALAKKH 
    MEMHGTVKAY RCSICQYKGN TLRGMRTHIR THFDKKTSDV NEELYMTCIF EEDASALSQE 
    LVTPTGASTT TGHDSMDHPS QMFNCDYCNY VSTYKGNVLR HMKLMHPHVA INSPSISPDT 
    RDQDVTSNPT TNQHSNSDVS NGEAPSFHIK SEPLDPPPTV NLVHENNNSP IATPHIKAEP 
    IEVGADAAPG GLVPPMTSPL GNSSSVAAAA AAAAEVMKKY CSTCDISFNY VKTYLAHKQF 
    YCKNKPIRPE ASDSPSPNHL GGGVAVGLGI GGLVGGHGQQ KNKENLQEAA IXESQLRWEA 
    QRKQLEWYYT CF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.