Details for: Rab3GAP1

Gene ID: 33338

Symbol: Rab3GAP1

Ensembl ID: FBgn0051935

Description: RAB3 GTPase activating protein subunit 1

Associated with

  • Copi-independent golgi-to-er retrograde traffic
    (R-DME-6811436)
  • Golgi-to-er retrograde transport
    (R-DME-8856688)
  • Intra-golgi and retrograde golgi-to-er traffic
    (R-DME-6811442)
  • Membrane trafficking
    (R-DME-199991)
  • Rab gefs exchange gtp for gdp on rabs
    (R-DME-8876198)
  • Rab regulation of trafficking
    (R-DME-9007101)
  • Vesicle-mediated transport
    (R-DME-5653656)
  • Cytoplasm
    (GO:0005737)
  • Endoplasmic reticulum tubular network
    (GO:0071782)
  • Establishment of protein localization to endoplasmic reticulum membrane
    (GO:0097051)
  • Excitatory postsynaptic potential
    (GO:0060079)
  • Gtpase activator activity
    (GO:0005096)
  • Lipid droplet organization
    (GO:0034389)
  • Macroautophagy
    (GO:0016236)
  • Positive regulation of autophagosome assembly
    (GO:2000786)
  • Positive regulation of endoplasmic reticulum tubular network organization
    (GO:1903373)
  • Positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization
    (GO:0061646)
  • Positive regulation of gtpase activity
    (GO:0043547)
  • Protein-containing complex
    (GO:0032991)
  • Regulation of calcium ion-dependent exocytosis of neurotransmitter
    (GO:1903233)
  • Regulation of rab protein signal transduction
    (GO:0032483)
  • Regulation of short-term neuronal synaptic plasticity
    (GO:0048172)
  • Small gtpase binding
    (GO:0031267)

Other Information

Genular Protein ID: 3466950104

Symbol: RB3GP_DROME

Name: N/A

UniProtKB Accession Codes:

Q9VQ26

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CTD 1 EMBL 1 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 1 GO 17 GeneTree 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OMA 1 PANTHER 2 PRO 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 Reactome 2 RefSeq 1 SMR 1 STRING 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

PubMed ID: 21338884

Title: Rab3-GAP controls the progression of synaptic homeostasis at a late stage of vesicle release.

PubMed ID: 21338884

DOI: 10.1016/j.neuron.2011.01.025

PubMed ID: 32248620

Title: The Warburg Micro Syndrome-associated Rab3GAP-Rab18 module promotes autolysosome maturation through the Vps34 Complex I.

PubMed ID: 32248620

DOI: 10.1111/febs.15313

Sequence Information:

  • Length: 916
  • Mass: 104431
  • Checksum: 7625F4D48BA54F1A
  • Sequence:
    • MAEEIDDNEF YRENFSADSD WEVFNAQLGE ILQKWDVSSD SETRNLKSEE IFSCNWKVER 
EKLDMLRNGI EVEYHQAILE DEELVRAEAK EITCLQRTSC HHDLMSTGNS FGPPIRSSQE 
LHILARIYGL RRFIVLHPVN PTLNYMRSTS EFNFFLSAVA VVSAEVQSLV PIFVQIYDPK 
WNYYTGVALA PALRTNFRLI GLEKAPPECR FLMGLLTLFR EKVPTSYTQA AMISVCTTYA 
LDTMRIRMPM YVPFDHGLSS EDIVVDGEVS HLEVQQFCAL PHGYKPESRT EIYLVYTWPE 
LSEHVAFDSE QRSDFVPAKA PLGKIYLSVE ASSYLSCCLR DYQSVAEVTR SLESFVGRNF 
SGTSSGAEAA SNPLDRITEH KLTKRRERSF ELPSQAGLTK RLPGPMTESE LSELLAYLFP 
DMHPEMALFP YAKKNFTDKF DPMRIKSAVP DSLVCRLSCL LATCHAHLGS VEGMAQVWAA 
FTRQLRLLWD NSLMVPGISA GFPDTRTCLL HQKLQMLNVC VERRVQREAN SKRKSEGMVG 
KASSEEEEDE DDDEGEFFDC DDLTAGAGSP TKAVLSLKPE GRLRRLNNER LLEEPDEYLY 
IPDTQEPVPK TEDQLQDDAE VMLKLGPGSG LTTQMMCTSL LSDMEAFKAA NPRGIMEDFI 
RWYSPKDWEE VTDELGQVKH QLSIRMTTEG NTWQKVWEQA QAVPVSRQKR LFDDTNEALK 
VLHYLETRKM HEIYNLTVIP LLHSAILKLA DILSNAELED LFSSQIEKLL SDLCRLSRSH 
SDELPSIKPL LDDLAELERR FYQFKCFERL SGYPKRSSLQ QVKLQFEEIL RNDNCCTIVN 
RRLTAAGDGT LYDILIPKLE EDMADRLISK DYIIRLDGDT KTTEKGLYLG PQFMRAIVTG 
EKLRLCGAFT ESTAFV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.