Details for: APLP2

Gene ID: 334

Symbol: APLP2

Ensembl ID: ENSG00000084234

Description: amyloid beta precursor like protein 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 663.5369
    Cell Significance Index: -103.2100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 397.6055
    Cell Significance Index: -100.8500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 261.3304
    Cell Significance Index: -123.3800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 257.3001
    Cell Significance Index: -104.5300
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 223.2957
    Cell Significance Index: -114.8600
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 184.3456
    Cell Significance Index: -123.7000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 109.5085
    Cell Significance Index: -104.5500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 93.3042
    Cell Significance Index: -115.0400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 42.9455
    Cell Significance Index: -115.0500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 30.1568
    Cell Significance Index: -119.0000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 27.2021
    Cell Significance Index: -83.5500
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 16.9653
    Cell Significance Index: -37.1300
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 9.5500
    Cell Significance Index: 73.6100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 6.2469
    Cell Significance Index: 115.4600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 5.8445
    Cell Significance Index: 69.6700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 4.3300
    Cell Significance Index: 2364.7300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 4.0897
    Cell Significance Index: 109.2000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 3.8094
    Cell Significance Index: 35.0800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 3.5312
    Cell Significance Index: 636.5600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 3.4277
    Cell Significance Index: 421.4700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 3.2494
    Cell Significance Index: 170.6100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 2.8031
    Cell Significance Index: 304.8900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.5172
    Cell Significance Index: 131.1200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.4032
    Cell Significance Index: 330.0300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 2.2108
    Cell Significance Index: 164.7700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.0261
    Cell Significance Index: 406.4400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.9236
    Cell Significance Index: 381.7400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.5994
    Cell Significance Index: 573.6700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.2517
    Cell Significance Index: 34.0700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.9716
    Cell Significance Index: 124.5500
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.9655
    Cell Significance Index: 11.9800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.9585
    Cell Significance Index: 27.6200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.9566
    Cell Significance Index: 49.6900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.7813
    Cell Significance Index: 540.4000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.6018
    Cell Significance Index: 33.7700
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 0.5898
    Cell Significance Index: 3.6300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.5610
    Cell Significance Index: 248.0300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5388
    Cell Significance Index: 53.3000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.5056
    Cell Significance Index: 932.5100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.4409
    Cell Significance Index: 323.2600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.4056
    Cell Significance Index: 24.9300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.3694
    Cell Significance Index: 23.2800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3490
    Cell Significance Index: 315.1400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2736
    Cell Significance Index: 12.8600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.2713
    Cell Significance Index: 4.6500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2646
    Cell Significance Index: 43.0300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.2637
    Cell Significance Index: 358.5100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.2604
    Cell Significance Index: 197.0900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.2306
    Cell Significance Index: 6.6100
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.1787
    Cell Significance Index: 2.0300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1698
    Cell Significance Index: 261.4700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1630
    Cell Significance Index: 307.0000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1403
    Cell Significance Index: 18.1300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1312
    Cell Significance Index: 4.6100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0858
    Cell Significance Index: 6.0700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.0712
    Cell Significance Index: 2.4700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0562
    Cell Significance Index: 9.6000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0251
    Cell Significance Index: 4.7900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0269
    Cell Significance Index: -19.9100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0532
    Cell Significance Index: -33.8000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0538
    Cell Significance Index: -5.5000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0828
    Cell Significance Index: -3.8600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0938
    Cell Significance Index: -58.6100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1014
    Cell Significance Index: -6.8200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1120
    Cell Significance Index: -3.1300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1301
    Cell Significance Index: -59.0500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1382
    Cell Significance Index: -77.9300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.2003
    Cell Significance Index: -9.0800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2189
    Cell Significance Index: -24.9900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2318
    Cell Significance Index: -6.1000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2431
    Cell Significance Index: -51.2000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.3071
    Cell Significance Index: -5.1400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.3371
    Cell Significance Index: -39.7500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.3587
    Cell Significance Index: -103.2200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.3643
    Cell Significance Index: -7.1100
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.3865
    Cell Significance Index: -8.9300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.4235
    Cell Significance Index: -61.5600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.4809
    Cell Significance Index: -55.0900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.5511
    Cell Significance Index: -42.2900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.6451
    Cell Significance Index: -75.1900
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.7258
    Cell Significance Index: -4.3900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.8080
    Cell Significance Index: -52.1300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.9090
    Cell Significance Index: -24.3200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.9984
    Cell Significance Index: -44.1600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -1.0083
    Cell Significance Index: -104.9900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -1.1662
    Cell Significance Index: -44.1600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -1.1727
    Cell Significance Index: -16.0000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.2370
    Cell Significance Index: -97.9700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.2533
    Cell Significance Index: -31.3300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.3499
    Cell Significance Index: -34.7000
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -1.5265
    Cell Significance Index: -26.9800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -1.5583
    Cell Significance Index: -33.7600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.5602
    Cell Significance Index: -49.9700
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: -1.5859
    Cell Significance Index: -13.9700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -1.7077
    Cell Significance Index: -36.3700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -1.7262
    Cell Significance Index: -49.2600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.7493
    Cell Significance Index: -107.2500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -1.7621
    Cell Significance Index: -42.2600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.8629
    Cell Significance Index: -54.8700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.9828
    Cell Significance Index: -53.1300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** APLP2 is a transmembrane protein with a short intracellular domain and a long extracellular domain, which is rich in EGF-like repeats and laminin-like domains. The protein is highly glycosylated, with multiple N-glycosylation sites, which may contribute to its stability and function. APLP2 is also known to interact with various proteins, including APP, amyloid precursor-like protein 3 (APLP3), and other extracellular proteins, such as heparin and laminin. The protein's expression is tightly regulated, with a high expression level in neurons and granule cells, which suggests its importance in CNS development and function. **Pathways and Functions** APLP2 is involved in various cellular processes, including: 1. **Axonogenesis**: APLP2 plays a crucial role in the development and maintenance of the axon, a critical component of neuronal function and connectivity. 2. **Central Nervous System Development**: APLP2 is essential for the development and maturation of neurons, including granule cells and stellate neurons. 3. **Platelet Activation**: APLP2 interacts with platelet receptors, such as integrins and G-protein coupled receptors, to regulate platelet activation and aggregation. 4. **Protein Metabolism**: APLP2 is involved in the regulation of protein trafficking and degradation, including the metabolism of APP and other extracellular proteins. 5. **Cell Signaling**: APLP2 interacts with various signaling molecules, including G-proteins and growth factors, to regulate cellular responses to external stimuli. **Clinical Significance** The dysregulation of APLP2 has been implicated in various diseases, including: 1. **Alzheimer's Disease**: APLP2 has been shown to be involved in the pathogenesis of Alzheimer's disease, where it is thought to contribute to the formation of amyloid plaques. 2. **Neurodegenerative Disorders**: APLP2 has been implicated in other neurodegenerative disorders, such as frontotemporal dementia and Parkinson's disease. 3. **Platelet-Related Disorders**: APLP2 has been shown to be involved in platelet-related disorders, such as thrombocytopenia and bleeding disorders. 4. **Cancer**: APLP2 has been implicated in cancer progression and metastasis, where it is thought to contribute to the regulation of cell migration and invasion. In conclusion, APLP2 is a multifunctional protein that plays a critical role in various cellular processes, including axonogenesis, CNS development, and platelet activation. Its dysregulation has been implicated in various diseases, highlighting the importance of further research into the mechanisms of APLP2 function and its role in human disease.

Genular Protein ID: 1267156402

Symbol: APLP2_HUMAN

Name: APPH

UniProtKB Accession Codes:

Q06481 B3KXX9 H7BXI4 Q13861 Q14594 Q14662 Q71U10 Q7M4L3 Q9BT36

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CDD 2 CTD 1 ChEBI 3 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 4 ELM 1 EMBL 13 Ensembl 6 ExpressionAtlas 1 GO 14 Gene3D 6 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 15 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 2 PRINTS 2 PRO 1 PROSITE 6 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 5 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 Reactome 3 RefSeq 5 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8485127

Title: Molecular cloning of the cDNA for a human amyloid precursor protein homolog: evidence for a multigene family.

PubMed ID: 8485127

DOI: 10.1021/bi00068a002

PubMed ID: 8220435

Title: Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor.

PubMed ID: 8220435

DOI: 10.1038/ng0993-95

PubMed ID: 7702756

Title: A human amyloid precursor-like protein is highly homologous to a mouse sequence-specific DNA-binding protein.

PubMed ID: 7702756

DOI: 10.1089/dna.1994.13.1137

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 7651835

Title: USF binds to the APB alpha sequence in the promoter of the amyloid beta-protein precursor gene.

PubMed ID: 7651835

DOI: 10.1093/nar/23.14.2734

PubMed ID: 11101689

Title: Expression and characterization of the human YWK-II gene, encoding a sperm membrane protein related to the alzheimer betaA4-amyloid precursor protein.

PubMed ID: 11101689

DOI: 10.1093/molehr/6.12.1069

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8307156

Title: Expression, purification and characterization of a Kunitz-type protease inhibitor domain from human amyloid precursor protein homolog.

PubMed ID: 8307156

DOI: 10.1016/0014-5793(94)80115-0

PubMed ID: 8855266

Title: Association of a novel human FE65-like protein with the cytoplasmic domain of the amyloid-beta precursor protein.

PubMed ID: 8855266

DOI: 10.1073/pnas.93.20.10832

PubMed ID: 10081969

Title: Molecular cloning of human Fe65L2 and its interaction with the Alzheimer's beta-amyloid precursor protein.

PubMed ID: 10081969

DOI: 10.1016/s0304-3940(98)00995-1

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 26091039

Title: A single kinase generates the majority of the secreted phosphoproteome.

PubMed ID: 26091039

DOI: 10.1016/j.cell.2015.05.028

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 32337544

Title: An affinity chromatography and glycoproteomics workflow to profile the chondroitin sulfate proteoglycans that interact with malarial VAR2CSA in the placenta and in cancer.

PubMed ID: 32337544

DOI: 10.1093/glycob/cwaa039

Sequence Information:

  • Length: 763
  • Mass: 86956
  • Checksum: CA3A7D6DDB8A28D0
  • Sequence:
    • MAATGTAAAA ATGRLLLLLL VGLTAPALAL AGYIEALAAN AGTGFAVAEP QIAMFCGKLN 
MHVNIQTGKW EPDPTGTKSC FETKEEVLQY CQEMYPELQI TNVMEANQRV SIDNWCRRDK 
KQCKSRFVTP FKCLVGEFVS DVLLVPEKCQ FFHKERMEVC ENHQHWHTVV KEACLTQGMT 
LYSYGMLLPC GVDQFHGTEY VCCPQTKIIG SVSKEEEEED EEEEEEEDEE EDYDVYKSEF 
PTEADLEDFT EAAVDEDDED EEEGEEVVED RDYYYDTFKG DDYNEENPTE PGSDGTMSDK 
EITHDVKAVC SQEAMTGPCR AVMPRWYFDL SKGKCVRFIY GGCGGNRNNF ESEDYCMAVC 
KAMIPPTPLP TNDVDVYFET SADDNEHARF QKAKEQLEIR HRNRMDRVKK EWEEAELQAK 
NLPKAERQTL IQHFQAMVKA LEKEAASEKQ QLVETHLARV EAMLNDRRRM ALENYLAALQ 
SDPPRPHRIL QALRRYVRAE NKDRLHTIRH YQHVLAVDPE KAAQMKSQVM THLHVIEERR 
NQSLSLLYKV PYVAQEIQEE IDELLQEQRA DMDQFTASIS ETPVDVRVSS EESEEIPPFH 
PFHPFPALPE NEDTQPELYH PMKKGSGVGE QDGGLIGAEE KVINSKNKVD ENMVIDETLD 
VKEMIFNAER VGGLEEERES VGPLREDFSL SSSALIGLLV IAVAIATVIV ISLVMLRKRQ 
YGTISHGIVE VDPMLTPEER HLNKMQNHGY ENPTYKYLEQ MQI

Genular Protein ID: 3589581016

Symbol: A0A140VJE9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A140VJE9

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 ExpressionAtlas 1 GO 7 Gene3D 6 InterPro 15 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 9 PROSITE-ProRule 1 Pfam 5 RefSeq 1 SAM 3 SMART 2 SMR 1 SUPFAM 4 VEuPathDB 1

Sequence Information:

  • Length: 751
  • Mass: 85487
  • Checksum: 788BCDC6E4487E18
  • Sequence:
    • MAATGTAAAA ATGRLLLLLL VGLTAPALAL AGYIEALAAN AGTGFAVAEP QIAMFCGKLN 
MHVNIQTGKW EPDPTGTKSC FETKEEVLQY CQEMYPELQI TNVMEANQRV SIDNWCRRDK 
KQCKSRFVTP FKCLVGEFVS DVLLVPEKCQ FFHKERMEVC ENHQHWHTVV KEACLTQGMT 
LYSYGMLLPC GVDQFHGTEY VCCPQTKIIG SVSKEEEEED EEEEEEEDEE EDYDVYKSEF 
PTEADLEDFT EAAVDEDDED EEEGEEVVED RDYYYDTFKG DDYNEENPTE PGSDGTMSDK 
EITHDVKAVC SQEAMTGPCR AVMPRWYFDL SKGKCVRFIY GGCGGNRNNF ESEDYCMAVC 
KAMIPPTPLP TNDVDVYFET SADDNEHARF QKAKEQLEIR HRNRMDRVKK EWEEAELQAK 
NLPKAERQTL IQHFQAMVKA LEKEAASEKQ QLVETHLARV EAMLNDRRRM ALENYLAALQ 
SDPPRPHRIL QALRRYVRAE NKDRLHTIRH YQHVLAVDPE KAAQMKSQVM THLHVIEERR 
NQSLSLLYKV PYVAQEIQEE IDELLQEQRA DMDQFTASIS ETPVDVRVSS EESEEIPPFH 
PFHPFPALPE NEGSGVGEQD GGLIGAEEKV INSKNKVDEN MVIDETLDVK EMIFNAERVG 
GLEEERESVG PLREDFSLSS SALIGLLVIA VAIATVIVIS LVMLRKRQYG TISHGIVEVD 
PMLTPEERHL NKMQNHGYEN PTYKYLEQMQ I

Genular Protein ID: 2499763155

Symbol: B4E3I5_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4E3I5

Database IDs:

ARBA 10 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 5 InterPro 12 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 6 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 RefSeq 1 SAM 3 SMART 1 SUPFAM 3

Sequence Information:

  • Length: 689
  • Mass: 78765
  • Checksum: CAE94A167A8506E0
  • Sequence:
    • MAAAATGRLL LLLLVGLTAP ALALAGYIEA LAANAGTGFA VAEPQIAMFC GKLNMHVNIQ 
TGKWEPDPTG TKSCFETKEE VLQYCQEMYP ELQITNVMEA NQRVSIDNWC RRDKKQCKSR 
FVTPFKCLVG EFVSDVLLVP EKCQFFHKER MEVCENHQHW HTVVKEACLT QGMTLYSYGM 
LLPCGVDQFH GTEYVCCPQT KIIGSVSKEE EEEDEEEEEE EDEEEDYDVY KSEFPTEADL 
EDFTEAAVDE DDEDEEEGEE VVEDRDYYYD TFKGDDYNEE NPTEPGSDGT MSDKEITHDV 
KVPPTPLPTN DVDVYFETSA DDNEHARFQK AKEQLEIRHR NRMDRVKKEW EEAELQAKNL 
PKAERQTLIQ HFQAMVKALE KEAASEKQQL VETHLARVEA MLNDRRRMAL ENYLAALQSD 
PPRPHRILQA LRRYVRAENK DRLHTIRHYQ HVLAVDPEKA AQMKSQVMTH LHVIEERRNQ 
SLSLLYKVPY VAQEIQEEID ELLQEQRADM DQFTASISET PVDVRVSSEE SEEIPPFHPF 
HPFPALPENE GSGVGEQDGG LIGAEEKVIN SKNKVDENMV IDETLDVKEM IFNAERVGGL 
EEERESVGPL REDFSLSSSA LIGLLVIAVA IATVIVISLV MLRKRQYGTI SHGIVEVDPM 
LTPEERHLNK MQNHGYENPT YKYLEQMQI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.