Rab5 | FBgn0014010 | NCBI 33418

Details for: Rab5

Gene ID: 33418

Symbol: Rab5

Ensembl ID: FBgn0014010

Description: Rab5

Associated with

Clathrin-mediated endocytosis
(R-DME-8856828)
Factors involved in megakaryocyte development and platelet production
(R-DME-983231)
Golgi associated vesicle biogenesis
(R-DME-432722)
Hemostasis
(R-DME-109582)
Immune system
(R-DME-168256)
Innate immune system
(R-DME-168249)
Membrane trafficking
(R-DME-199991)
Metabolism
(R-DME-1430728)
Metabolism of lipids
(R-DME-556833)
Metabolism of proteins
(R-DME-392499)
Neutrophil degranulation
(R-DME-6798695)
Phospholipid metabolism
(R-DME-1483257)
Pi metabolism
(R-DME-1483255)
Post-translational protein modification
(R-DME-597592)
Rab gefs exchange gtp for gdp on rabs
(R-DME-8876198)
Rab geranylgeranylation
(R-DME-8873719)
Rab regulation of trafficking
(R-DME-9007101)
Synthesis of pips at the plasma membrane
(R-DME-1660499)
Tbc/rabgaps
(R-DME-8854214)
Trans-golgi network vesicle budding
(R-DME-199992)
Axon extension
(GO:0048675)
Axonogenesis
(GO:0007409)
Axon terminus
(GO:0043679)
Border follicle cell migration
(GO:0007298)
Cell cortex
(GO:0005938)
Cellularization
(GO:0007349)
Clathrin-dependent endocytosis involved in vitellogenesis
(GO:0061883)
Dendrite morphogenesis
(GO:0048813)
Dorsal closure, amnioserosa morphology change
(GO:0046664)
Early endosome
(GO:0005769)
Endocytic patch
(GO:0061645)
Endocytic vesicle
(GO:0030139)
Endocytosis
(GO:0006897)
Endomembrane system
(GO:0012505)
Endosomal vesicle fusion
(GO:0034058)
Endosome organization
(GO:0007032)
Endosome transport via multivesicular body sorting pathway
(GO:0032509)
Establishment or maintenance of apical/basal cell polarity
(GO:0035088)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Imaginal disc-derived male genitalia morphogenesis
(GO:0048803)
Intracellular protein transport
(GO:0006886)
Multivesicular body assembly
(GO:0036258)
Multivesicular body membrane
(GO:0032585)
Nervous system development
(GO:0007399)
Neuronal cell body
(GO:0043025)
Notch receptor processing
(GO:0007220)
Oogenesis
(GO:0048477)
Plasma membrane
(GO:0005886)
Plasma membrane to endosome transport
(GO:0048227)
Presynaptic endosome
(GO:0098830)
Protein binding
(GO:0005515)
Rab protein signal transduction
(GO:0032482)
Receptor-mediated endocytosis
(GO:0006898)
Regulation of endocytosis
(GO:0030100)
Regulation of synapse structure or activity
(GO:0050803)
Symbiont entry into host cell
(GO:0046718)
Synapse
(GO:0045202)
Synaptic vesicle
(GO:0008021)
Synaptic vesicle endocytosis
(GO:0048488)
Synaptic vesicle endosomal processing
(GO:0099532)
Synaptic vesicle to endosome fusion
(GO:0016189)
Terminal bouton
(GO:0043195)
Vesicle
(GO:0031982)
Vesicle-mediated transport
(GO:0016192)
Wing disc development
(GO:0035220)

Other Information

Proteins

RAB5_DROME

Genular Protein ID: 3881486195

Symbol: RAB5_DROME

Name: N/A

UniProtKB Accession Codes:

Q9V3I2

Database IDs:

Citations:

PubMed ID: 9197407

Title: Molecular cloning and characterization of Drosophila genes encoding small GTPases of the rab and rho families.

PubMed ID: 9197407

DOI: 10.1007/s004380050443

PubMed ID: 12743108

Title: Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release.

PubMed ID: 12743108

DOI: 10.1083/jcb.200211087

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 11136982

Title: Gradient formation of the TGF-beta homolog Dpp.

PubMed ID: 11136982

DOI: 10.1016/s0092-8674(00)00200-2

PubMed ID: 12876219

Title: An essential role of Rab5 in uniformity of synaptic vesicle size.

PubMed ID: 12876219

DOI: 10.1242/jcs.00676

PubMed ID: 19050045

Title: Interplay between Rab5 and PtdIns(4,5)P2 controls early endocytosis in the Drosophila germline.

PubMed ID: 19050045

DOI: 10.1242/jcs.033027

PubMed ID: 23418349

Title: Dmon1 controls recruitment of Rab7 to maturing endosomes in Drosophila.

PubMed ID: 23418349

DOI: 10.1242/jcs.114934

PubMed ID: 27559127

Title: The Ccz1-Mon1-Rab7 module and Rab5 control distinct steps of autophagy.

PubMed ID: 27559127

DOI: 10.1091/mbc.e16-03-0205

PubMed ID: 32391792

Title: A conserved and regulated mechanism drives endosomal Rab transition.

PubMed ID: 32391792

DOI: 10.7554/elife.56090

Sequence Information:

Length: 219
Mass: 23959
Checksum: BFA3A28955B7F15D
Sequence:

MATTPRSGGA SGTGTAQRPN GTSQNKSCQF KLVLLGESAV GKSSLVLRFV KGQFHEYQES 
TIGAAFLTQT ICIEDTVVKF EIWDTAGQER YHSLAPMYYR GAQAAIVVYD IQNQDSFQRA 
KTWVKELHKQ ASPNIVIALA GNKADLSNIR VVEFDEAKQY AEENGLLFME TSAKTGMNVN 
DIFLAIAKKL PKNDGANNQG TSIRPTGTET NRPTNNCCK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rab5

Associated with

Other Information

Molecular cloning and characterization of Drosophila genes encoding small GTPases of the rab and rho families. PubMed ID: 9197407

Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release. PubMed ID: 12743108

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila full-length cDNA resource. PubMed ID: 12537569

Gradient formation of the TGF-beta homolog Dpp. PubMed ID: 11136982

An essential role of Rab5 in uniformity of synaptic vesicle size. PubMed ID: 12876219

Interplay between Rab5 and PtdIns(4,5)P2 controls early endocytosis in the Drosophila germline. PubMed ID: 19050045

Dmon1 controls recruitment of Rab7 to maturing endosomes in Drosophila. PubMed ID: 23418349

The Ccz1-Mon1-Rab7 module and Rab5 control distinct steps of autophagy. PubMed ID: 27559127

A conserved and regulated mechanism drives endosomal Rab transition. PubMed ID: 32391792