Details for: aph 1

Gene ID: 33467

Symbol: aph 1

Ensembl ID: FBgn0031458

Description: anterior pharynx defective 1

Associated with

Other Information

Genular Protein ID: 737360739

Symbol: APH1_DROME

Name: Gamma-secretase subunit Aph-1

UniProtKB Accession Codes:

Q9VQG2

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DNASU 1 EMBL 3 EnsemblMetazoa 2 ExpressionAtlas 1 FlyBase 1 GO 13 GeneTree 1 Genevisible 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 Reactome 2 RefSeq 2 SMR 1 STRING 1 SignaLink 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 12110170

Title: aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation.

PubMed ID: 12110170

DOI: 10.1016/s1534-5807(02)00189-2

PubMed ID: 12660785

Title: The role of presenilin cofactors in the gamma-secretase complex.

PubMed ID: 12660785

DOI: 10.1038/nature01506

Sequence Information:

  • Length: 238
  • Mass: 26437
  • Checksum: C61A24518DCA150F
  • Sequence:
    • MTLPEFFGCT FIAFGPPFAL FVFTIANDPV RIIILIAAAF FWLLSLLISS LWYALIPLKE 
FLAFGVVFSV CFQEAFRYII YRILRSTEQG LHAVAEDTRV TDNKHILAYV SGLGFGIISG 
MFALVNVLAD MSGPGTMGLK GGTELFFVTS AAQALSIILL HTFWSVIFFN AFDTNNYIHI 
GYVVFSHLFV SLITLLNANE LYTTTLLINY LVTILTGVLA FRVAGGTSRS FRKFITCQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.