Details for: RpS21

Gene ID: 33487

Symbol: RpS21

Ensembl ID: FBgn0015521

Description: Ribosomal protein S21

Associated with

  • Activation of the mrna upon binding of the cap-binding complex and eifs, and subsequent binding to 43s
    (R-DME-72662)
  • Cap-dependent translation initiation
    (R-DME-72737)
  • Eukaryotic translation initiation
    (R-DME-72613)
  • Formation of a pool of free 40s subunits
    (R-DME-72689)
  • Formation of the ternary complex, and subsequently, the 43s complex
    (R-DME-72695)
  • Gtp hydrolysis and joining of the 60s ribosomal subunit
    (R-DME-72706)
  • L13a-mediated translational silencing of ceruloplasmin expression
    (R-DME-156827)
  • Metabolism of proteins
    (R-DME-392499)
  • Metabolism of rna
    (R-DME-8953854)
  • Nonsense-mediated decay (nmd)
    (R-DME-927802)
  • Nonsense mediated decay (nmd) enhanced by the exon junction complex (ejc)
    (R-DME-975957)
  • Nonsense mediated decay (nmd) independent of the exon junction complex (ejc)
    (R-DME-975956)
  • Ribosomal scanning and start codon recognition
    (R-DME-72702)
  • Srp-dependent cotranslational protein targeting to membrane
    (R-DME-1799339)
  • Translation initiation complex formation
    (R-DME-72649)
  • Cytoplasmic translation
    (GO:0002181)
  • Cytosolic ribosome
    (GO:0022626)
  • Cytosolic small ribosomal subunit
    (GO:0022627)
  • Endonucleolytic cleavage in its1 to separate ssu-rrna from 5.8s rrna and lsu-rrna from tricistronic rrna transcript (ssu-rrna, 5.8s rrna, lsu-rrna)
    (GO:0000447)
  • Endonucleolytic cleavage to generate mature 3'-end of ssu-rrna from (ssu-rrna, 5.8s rrna, lsu-rrna)
    (GO:0000461)
  • Lymph gland development
    (GO:0048542)
  • Regulation of cell population proliferation
    (GO:0042127)
  • Ribosome
    (GO:0005840)
  • Ribosome binding
    (GO:0043022)
  • Structural constituent of ribosome
    (GO:0003735)
  • Translation
    (GO:0006412)

Other Information

Genular Protein ID: 885484237

Symbol: RS21_DROME

Name: N/A

UniProtKB Accession Codes:

O76927 A4V027

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 5 EMDB 3 EnsemblMetazoa 5 ExpressionAtlas 1 FlyBase 1 GO 12 Gene3D 1 GeneTree 1 GenomeRNAi 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIRSF 1 PRO 1 PROSITE 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 Reactome 9 RefSeq 5 SMR 1 STRING 1 SignaLink 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10022917

Title: Down-regulation of RpS21, a putative translation initiation factor interacting with P40, produces viable minute imagos and larval lethality with overgrown hematopoietic organs and imaginal discs.

PubMed ID: 10022917

DOI: 10.1128/mcb.19.3.2308

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 23636399

Title: Structures of the human and Drosophila 80S ribosome.

PubMed ID: 23636399

DOI: 10.1038/nature12104

Sequence Information:

  • Length: 83
  • Mass: 9167
  • Checksum: DDFB9D498B3E1E05
  • Sequence:
    • MENDAGENVD LYVPRKCSAS NRIIHAKDHA SVQLSIVDVD PETGRQTDGS KTYAICGEIR 
RMGESDDCIV RLAKKDGIIT KNF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.