Details for: APOB

Gene ID: 338

Symbol: APOB

Ensembl ID: ENSG00000084674

Description: apolipoprotein B

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 51.3347
    Cell Significance Index: 757.7000
  • Cell Name: liver dendritic cell (CL2000055)
    Fold Change: 46.0850
    Cell Significance Index: 121.5700
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 18.2933
    Cell Significance Index: 308.1500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 16.7136
    Cell Significance Index: -6.7900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 12.7961
    Cell Significance Index: 191.7400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 6.8774
    Cell Significance Index: 1364.8500
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: 5.4563
    Cell Significance Index: 20.5500
  • Cell Name: precursor cell (CL0011115)
    Fold Change: 4.2661
    Cell Significance Index: 32.3500
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 3.9306
    Cell Significance Index: 22.6400
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: 2.9005
    Cell Significance Index: 7.7700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 2.0674
    Cell Significance Index: 59.5700
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: 1.9474
    Cell Significance Index: 6.7800
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.7208
    Cell Significance Index: 13.5900
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.5832
    Cell Significance Index: 15.6200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.3863
    Cell Significance Index: 44.4000
  • Cell Name: inflammatory macrophage (CL0000863)
    Fold Change: 1.2793
    Cell Significance Index: 9.8300
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 1.0889
    Cell Significance Index: 4.7400
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.8023
    Cell Significance Index: 12.0900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.6413
    Cell Significance Index: 44.3500
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.5402
    Cell Significance Index: 13.0900
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 0.5333
    Cell Significance Index: 5.3800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.4334
    Cell Significance Index: 26.0200
  • Cell Name: colonocyte (CL1000347)
    Fold Change: 0.4159
    Cell Significance Index: 2.5700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4099
    Cell Significance Index: 8.8800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3809
    Cell Significance Index: 41.4400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.3785
    Cell Significance Index: 29.0500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3725
    Cell Significance Index: 70.8900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3539
    Cell Significance Index: 319.5400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3465
    Cell Significance Index: 56.3600
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.2919
    Cell Significance Index: 4.9100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2816
    Cell Significance Index: 7.0400
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 0.2425
    Cell Significance Index: 3.2700
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.1930
    Cell Significance Index: 1.8400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.1385
    Cell Significance Index: 2.9500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0763
    Cell Significance Index: 7.5500
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.0725
    Cell Significance Index: 1.0700
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.0526
    Cell Significance Index: 0.5500
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.0475
    Cell Significance Index: 0.6800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0474
    Cell Significance Index: 1.2700
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 0.0459
    Cell Significance Index: 0.4200
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 0.0223
    Cell Significance Index: 0.2300
  • Cell Name: stem cell (CL0000034)
    Fold Change: 0.0179
    Cell Significance Index: 0.1300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0111
    Cell Significance Index: 0.3900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0100
    Cell Significance Index: 2.8800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0020
    Cell Significance Index: 3.7300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0002
    Cell Significance Index: 0.3800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0001
    Cell Significance Index: -0.0400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0004
    Cell Significance Index: -0.7300
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.0008
    Cell Significance Index: -0.0100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0012
    Cell Significance Index: -0.9000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0015
    Cell Significance Index: -2.0600
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0016
    Cell Significance Index: -0.0700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0018
    Cell Significance Index: -0.2100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0020
    Cell Significance Index: -0.2700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0033
    Cell Significance Index: -1.8500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0054
    Cell Significance Index: -4.1000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0083
    Cell Significance Index: -5.2900
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0083
    Cell Significance Index: -0.1200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0088
    Cell Significance Index: -1.7700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0106
    Cell Significance Index: -4.8100
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.0135
    Cell Significance Index: -0.1900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0152
    Cell Significance Index: -0.6900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0160
    Cell Significance Index: -3.3700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0187
    Cell Significance Index: -3.1900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0245
    Cell Significance Index: -1.5100
  • Cell Name: enterocyte (CL0000584)
    Fold Change: -0.0258
    Cell Significance Index: -0.1600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0260
    Cell Significance Index: -2.9800
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.0311
    Cell Significance Index: -0.4300
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: -0.0314
    Cell Significance Index: -0.3700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0325
    Cell Significance Index: -5.8700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0332
    Cell Significance Index: -3.4000
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0342
    Cell Significance Index: -0.4900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0368
    Cell Significance Index: -3.8300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0392
    Cell Significance Index: -5.7000
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: -0.0455
    Cell Significance Index: -0.3200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0457
    Cell Significance Index: -2.1300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0483
    Cell Significance Index: -5.9400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0521
    Cell Significance Index: -2.6300
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0537
    Cell Significance Index: -2.2000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0584
    Cell Significance Index: -3.0400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0649
    Cell Significance Index: -1.8200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0663
    Cell Significance Index: -1.7100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0681
    Cell Significance Index: -2.2300
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0688
    Cell Significance Index: -0.9000
  • Cell Name: M cell of gut (CL0000682)
    Fold Change: -0.0732
    Cell Significance Index: -0.6100
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -0.0732
    Cell Significance Index: -0.9200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0802
    Cell Significance Index: -4.5000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0827
    Cell Significance Index: -1.7300
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0832
    Cell Significance Index: -2.0300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0844
    Cell Significance Index: -2.9600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0889
    Cell Significance Index: -2.8300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0920
    Cell Significance Index: -1.8000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0936
    Cell Significance Index: -4.1400
  • Cell Name: urothelial cell (CL0000731)
    Fold Change: -0.0961
    Cell Significance Index: -0.6700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1027
    Cell Significance Index: -3.0300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1048
    Cell Significance Index: -3.9700
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.1053
    Cell Significance Index: -2.6300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1098
    Cell Significance Index: -5.1600
  • Cell Name: plasmablast (CL0000980)
    Fold Change: -0.1164
    Cell Significance Index: -1.0800
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.1176
    Cell Significance Index: -3.7200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** APOB is a large, multifunctional protein with a molecular weight of approximately 515 kDa. It consists of 660 amino acid residues and is composed of several distinct domains, including the APOB-100 (ApoB100) domain, which is essential for lipoprotein assembly and transport. APOB is highly glycosylated, with 99% of the protein being post-translationally modified by N-linked glycosylation. This modification is critical for the protein's stability, function, and interactions with other lipoproteins and immune cells. APOB is highly expressed in the liver and intestines, where it plays a central role in lipid metabolism and the assembly of lipoproteins. It is also present in smaller amounts in other tissues, including the brain, adipose tissue, and immune cells. **Pathways and Functions** APOB is involved in various biological pathways, including: 1. **Lipid Metabolism**: APOB plays a critical role in the assembly, transport, and clearance of lipoproteins, including LDL and VLDL. It is involved in the regulation of cholesterol homeostasis and the transport of lipids to peripheral tissues. 2. **Immune Function**: APOB is recognized for its role in modulating immune responses, including the regulation of macrophage-derived foam cell differentiation and the scavenging of pathogens by immune cells. 3. **Cell Signaling**: APOB interacts with various signaling molecules, including growth factors, cytokines, and chemokines, to regulate cellular responses to stimuli. 4. **Cholesterol Transport**: APOB is involved in the transport of cholesterol from peripheral tissues to the liver for excretion or storage. **Clinical Significance** APOB is an important biomarker for various diseases, including: 1. **Atherosclerosis**: Elevated APOB levels are associated with an increased risk of atherosclerosis, a condition characterized by the buildup of fatty deposits in arterial walls. 2. **Hypertension**: APOB is involved in the regulation of blood pressure, and elevated levels are associated with an increased risk of hypertension. 3. **Diabetes**: APOB is involved in the regulation of glucose metabolism, and elevated levels are associated with an increased risk of type 2 diabetes. 4. **Cancer**: APOB is involved in the regulation of cell growth and differentiation, and altered levels have been implicated in various types of cancer. In conclusion, APOB is a multifunctional protein that plays a critical role in lipid metabolism, immune function, and cell signaling. Its dysregulation has been implicated in various diseases, including atherosclerosis, hypertension, diabetes, and cancer. Further research is needed to fully elucidate the mechanisms by which APOB regulates these processes and to develop novel therapeutic strategies for the treatment of these diseases.

Genular Protein ID: 1095522773

Symbol: APOB_HUMAN

Name: Apolipoprotein B-100

UniProtKB Accession Codes:

P04114 O00502 P78479 P78480 P78481 Q13779 Q13785 Q13786 Q13787 Q13788 Q4ZG63 Q53QC8 Q7Z600 Q9UMN0

Database IDs:

ABCD 1 AGR 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CPTAC 8 CPTC 1 CTD 1 CarbonylDB 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 4 EMBL 40 Ensembl 1 ExpressionAtlas 1 GO 58 Gene3D 3 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PIR 1 PRIDE 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 20 RefSeq 1 SIGNOR 1 SMART 2 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3763409

Title: Complete cDNA and derived protein sequence of human apolipoprotein B-100.

PubMed ID: 3763409

DOI: 10.1093/nar/14.18.7501

PubMed ID: 3652907

Title: DNA sequence of the human apolipoprotein B gene.

PubMed ID: 3652907

DOI: 10.1089/dna.1987.6.363

PubMed ID: 3759943

Title: The complete cDNA and amino acid sequence of human apolipoprotein B-100.

PubMed ID: 3759943

DOI: 10.1016/s0021-9258(18)69248-8

PubMed ID: 3464946

Title: Human liver apolipoprotein B-100 cDNA: complete nucleic acid and derived amino acid sequence.

PubMed ID: 3464946

DOI: 10.1073/pnas.83.21.8142

PubMed ID: 3030729

Title: The complete sequence and structural analysis of human apolipoprotein B-100: relationship between apoB-100 and apoB-48 forms.

PubMed ID: 3030729

DOI: 10.1002/j.1460-2075.1986.tb04675.x

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 3461454

Title: Analysis of cDNA clones encoding the entire B-26 region of human apolipoprotein B.

PubMed ID: 3461454

DOI: 10.1073/pnas.83.15.5678

PubMed ID: 3513177

Title: Isolation of a cDNA clone encoding the amino-terminal region of human apolipoprotein B.

PubMed ID: 3513177

DOI: 10.1073/pnas.83.5.1467

PubMed ID: 2115173

Title: Isolation and characterization of sulfhydryl and disulfide peptides of human apolipoprotein B-100.

PubMed ID: 2115173

DOI: 10.1073/pnas.87.14.5523

PubMed ID: 3001697

Title: Human apolipoprotein B-100: cloning, analysis of liver mRNA, and assignment of the gene to chromosome 2.

PubMed ID: 3001697

DOI: 10.1073/pnas.82.24.8340

PubMed ID: 3860836

Title: A partial cDNA clone for human apolipoprotein B.

PubMed ID: 3860836

DOI: 10.1073/pnas.82.15.4983

PubMed ID: 6373369

Title: Human apolipoprotein B: partial amino acid sequence.

PubMed ID: 6373369

DOI: 10.1016/0014-5793(84)81378-2

PubMed ID: 2567736

Title: Hypobetalipoproteinemia due to an apolipoprotein B gene exon 21 deletion derived by Alu-Alu recombination.

PubMed ID: 2567736

DOI: 10.1016/s0021-9258(18)60477-6

PubMed ID: 2883086

Title: Analysis of the human apolipoprotein B gene; complete structure of the B-74 region.

PubMed ID: 2883086

DOI: 10.1016/0378-1119(86)90383-5

PubMed ID: 3676265

Title: Structural comparison of human apolipoproteins B-48 and B-100.

PubMed ID: 3676265

DOI: 10.1021/bi00391a040

PubMed ID: 3841204

Title: Molecular cloning of human apolipoprotein B cDNA.

PubMed ID: 3841204

DOI: 10.1093/nar/13.24.8813

PubMed ID: 3621347

Title: A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine.

PubMed ID: 3621347

DOI: 10.1016/0092-8674(87)90510-1

PubMed ID: 2450346

Title: Human apolipoprotein B (apoB) mRNA: identification of two distinct apoB mRNAs, an mRNA with the apoB-100 sequence and an apoB mRNA containing a premature in-frame translational stop codon, in both liver and intestine.

PubMed ID: 2450346

DOI: 10.1073/pnas.85.6.1772

PubMed ID: 3426612

Title: Carboxyl terminal analysis of human B-48 protein confirms the novel mechanism proposed for chain termination.

PubMed ID: 3426612

DOI: 10.1016/0006-291x(87)90537-7

PubMed ID: 2445342

Title: Identification of a novel in-frame translational stop codon in human intestine apoB mRNA.

PubMed ID: 2445342

DOI: 10.1016/0006-291x(87)91107-7

PubMed ID: 3903660

Title: Human apolipoprotein B: identification of cDNA clones and characterization of mRNA.

PubMed ID: 3903660

DOI: 10.1093/nar/13.19.6937

PubMed ID: 2994225

Title: Human apolipoprotein B: structure of carboxyl-terminal domains, sites of gene expression, and chromosomal localization.

PubMed ID: 2994225

DOI: 10.1126/science.2994225

PubMed ID: 2932736

Title: Molecular cloning and expression of partial cDNAs and deduced amino acid sequence of a carboxyl-terminal fragment of human apolipoprotein B-100.

PubMed ID: 2932736

DOI: 10.1073/pnas.82.21.7265

PubMed ID: 3841481

Title: Molecular cloning of human LDL apolipoprotein B cDNA. Evidence for more than one gene per haploid genome.

PubMed ID: 3841481

DOI: 10.1016/0021-9150(85)90073-5

PubMed ID: 3024665

Title: Isolation, expression and characterization of a human apolipoprotein B 100-specific cDNA clone.

PubMed ID: 3024665

DOI: 10.1515/bchm3.1986.367.2.1077

PubMed ID: 3659919

Title: Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific in-frame stop codon.

PubMed ID: 3659919

DOI: 10.1126/science.3659919

PubMed ID: 3773997

Title: Complete protein sequence and identification of structural domains of human apolipoprotein B.

PubMed ID: 3773997

DOI: 10.1038/323734a0

PubMed ID: 3095664

Title: Sequence, structure, receptor-binding domains and internal repeats of human apolipoprotein B-100.

PubMed ID: 3095664

DOI: 10.1038/323738a0

PubMed ID: 3087360

Title: Apolipoprotein B is a calcium binding protein.

PubMed ID: 3087360

DOI: 10.1016/0006-291x(86)91237-4

PubMed ID: 10679026

Title: Palmitoylation of apolipoprotein B is required for proper intracellular sorting and transport of cholesteroyl esters and triglycerides.

PubMed ID: 10679026

DOI: 10.1091/mbc.11.2.721

PubMed ID: 14760718

Title: Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.

PubMed ID: 14760718

DOI: 10.1002/pmic.200300556

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 16548883

Title: Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

PubMed ID: 16548883

DOI: 10.1111/j.1462-5822.2005.00644.x

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20686565

Title: Biological, clinical and population relevance of 95 loci for blood lipids.

PubMed ID: 20686565

DOI: 10.1038/nature09270

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21981844

Title: A novel mutation of apolipoprotein B in a French Canadian family with homozygous hypobetalipoproteinemia.

PubMed ID: 21981844

DOI: 10.1016/j.jacl.2011.06.014

PubMed ID: 22580899

Title: Proprotein convertase subtilisin/kexin type 9 interacts with apolipoprotein B and prevents its intracellular degradation, irrespective of the low-density lipoprotein receptor.

PubMed ID: 22580899

DOI: 10.1161/atvbaha.112.250043

PubMed ID: 24916387

Title: C to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47.

PubMed ID: 24916387

DOI: 10.15252/embr.201438450

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26091039

Title: A single kinase generates the majority of the secreted phosphoproteome.

PubMed ID: 26091039

DOI: 10.1016/j.cell.2015.05.028

PubMed ID: 26224785

Title: A novel abetalipoproteinemia missense mutation highlights the importance of N-Terminal beta-barrel in microsomal triglyceride transfer protein function.

PubMed ID: 26224785

DOI: 10.1161/circgenetics.115.001106

PubMed ID: 28183703

Title: AUP1 (Ancient Ubiquitous Protein 1) Is a Key Determinant of Hepatic Very-Low-Density Lipoprotein Assembly and Secretion.

PubMed ID: 28183703

DOI: 10.1161/atvbaha.117.309000

PubMed ID: 1979313

Title: Detection by denaturing gradient gel electrophoresis of a new polymorphism in the apolipoprotein B gene.

PubMed ID: 1979313

DOI: 10.1007/bf00205183

PubMed ID: 2563166

Title: Association between a specific apolipoprotein B mutation and familial defective apolipoprotein B-100.

PubMed ID: 2563166

DOI: 10.1073/pnas.86.2.587

PubMed ID: 2216805

Title: Sequence polymorphism in the human apoB gene at position 8344.

PubMed ID: 2216805

DOI: 10.1093/nar/18.19.5922-a

PubMed ID: 7883971

Title: Familial ligand-defective apolipoprotein B. Identification of a new mutation that decreases LDL receptor binding affinity.

PubMed ID: 7883971

DOI: 10.1172/jci117772

PubMed ID: 8889592

Title: Detection of new variants in the apolipoprotein B (Apo B) gene by PCR-SSCP.

PubMed ID: 8889592

DOI: 10.1002/(sici)1098-1004(1996)8:3<282::aid-humu16>3.0.co;2-z

PubMed ID: 9259199

Title: Familial ligand-defective apolipoprotein B-100: simultaneous detection of the Arg3500-->Gln and Arg3531-->Cys mutations in a French population.

PubMed ID: 9259199

DOI: 10.1002/(sici)1098-1004(1997)10:2<160::aid-humu8>3.0.co;2-o

PubMed ID: 9490296

Title: Screening for mutations of the apolipoprotein B gene causing hypocholesterolemia.

PubMed ID: 9490296

DOI: 10.1007/s004390050651

PubMed ID: 12551903

Title: A novel nontruncating APOB gene mutation, R463W, causes familial hypobetalipoproteinemia.

PubMed ID: 12551903

DOI: 10.1074/jbc.m300235200

PubMed ID: 14732481

Title: Hypobetalipoproteinemia with an apparently recessive inheritance due to a 'de novo' mutation of apolipoprotein B.

PubMed ID: 14732481

DOI: 10.1016/j.bbadis.2003.11.002

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 21382890

Title: Molecular basis of autosomal dominant hypercholesterolemia: assessment in a large cohort of hypercholesterolemic children.

PubMed ID: 21382890

DOI: 10.1161/circulationaha.110.979450

PubMed ID: 22028381

Title: Quantitative detection of single amino acid polymorphisms by targeted proteomics.

PubMed ID: 22028381

DOI: 10.1093/jmcb/mjr024

PubMed ID: 22095935

Title: Genetic variation in APOB, PCSK9, and ANGPTL3 in carriers of pathogenic autosomal dominant hypercholesterolemic mutations with unexpected low LDL-Cl Levels.

PubMed ID: 22095935

DOI: 10.1002/humu.21660

PubMed ID: 27206948

Title: Novel APOB missense variants, A224T and V925L, in a black South African woman with marked hypocholesterolemia.

PubMed ID: 27206948

DOI: 10.1016/j.jacl.2016.01.006

Sequence Information:

  • Length: 4563
  • Mass: 515545
  • Checksum: D1073B2D5172A370
  • Sequence:
    • MDPPRPALLA LLALPALLLL LLAGARAEEE MLENVSLVCP KDATRFKHLR KYTYNYEAES 
SSGVPGTADS RSATRINCKV ELEVPQLCSF ILKTSQCTLK EVYGFNPEGK ALLKKTKNSE 
EFAAAMSRYE LKLAIPEGKQ VFLYPEKDEP TYILNIKRGI ISALLVPPET EEAKQVLFLD 
TVYGNCSTHF TVKTRKGNVA TEISTERDLG QCDRFKPIRT GISPLALIKG MTRPLSTLIS 
SSQSCQYTLD AKRKHVAEAI CKEQHLFLPF SYKNKYGMVA QVTQTLKLED TPKINSRFFG 
EGTKKMGLAF ESTKSTSPPK QAEAVLKTLQ ELKKLTISEQ NIQRANLFNK LVTELRGLSD 
EAVTSLLPQL IEVSSPITLQ ALVQCGQPQC STHILQWLKR VHANPLLIDV VTYLVALIPE 
PSAQQLREIF NMARDQRSRA TLYALSHAVN NYHKTNPTGT QELLDIANYL MEQIQDDCTG 
DEDYTYLILR VIGNMGQTME QLTPELKSSI LKCVQSTKPS LMIQKAAIQA LRKMEPKDKD 
QEVLLQTFLD DASPGDKRLA AYLMLMRSPS QADINKIVQI LPWEQNEQVK NFVASHIANI 
LNSEELDIQD LKKLVKEALK ESQLPTVMDF RKFSRNYQLY KSVSLPSLDP ASAKIEGNLI 
FDPNNYLPKE SMLKTTLTAF GFASADLIEI GLEGKGFEPT LEALFGKQGF FPDSVNKALY 
WVNGQVPDGV SKVLVDHFGY TKDDKHEQDM VNGIMLSVEK LIKDLKSKEV PEARAYLRIL 
GEELGFASLH DLQLLGKLLL MGARTLQGIP QMIGEVIRKG SKNDFFLHYI FMENAFELPT 
GAGLQLQISS SGVIAPGAKA GVKLEVANMQ AELVAKPSVS VEFVTNMGII IPDFARSGVQ 
MNTNFFHESG LEAHVALKAG KLKFIIPSPK RPVKLLSGGN TLHLVSTTKT EVIPPLIENR 
QSWSVCKQVF PGLNYCTSGA YSNASSTDSA SYYPLTGDTR LELELRPTGE IEQYSVSATY 
ELQREDRALV DTLKFVTQAE GAKQTEATMT FKYNRQSMTL SSEVQIPDFD VDLGTILRVN 
DESTEGKTSY RLTLDIQNKK ITEVALMGHL SCDTKEERKI KGVISIPRLQ AEARSEILAH 
WSPAKLLLQM DSSATAYGST VSKRVAWHYD EEKIEFEWNT GTNVDTKKMT SNFPVDLSDY 
PKSLHMYANR LLDHRVPQTD MTFRHVGSKL IVAMSSWLQK ASGSLPYTQT LQDHLNSLKE 
FNLQNMGLPD FHIPENLFLK SDGRVKYTLN KNSLKIEIPL PFGGKSSRDL KMLETVRTPA 
LHFKSVGFHL PSREFQVPTF TIPKLYQLQV PLLGVLDLST NVYSNLYNWS ASYSGGNTST 
DHFSLRARYH MKADSVVDLL SYNVQGSGET TYDHKNTFTL SCDGSLRHKF LDSNIKFSHV 
EKLGNNPVSK GLLIFDASSS WGPQMSASVH LDSKKKQHLF VKEVKIDGQF RVSSFYAKGT 
YGLSCQRDPN TGRLNGESNL RFNSSYLQGT NQITGRYEDG TLSLTSTSDL QSGIIKNTAS 
LKYENYELTL KSDTNGKYKN FATSNKMDMT FSKQNALLRS EYQADYESLR FFSLLSGSLN 
SHGLELNADI LGTDKINSGA HKATLRIGQD GISTSATTNL KCSLLVLENE LNAELGLSGA 
SMKLTTNGRF REHNAKFSLD GKAALTELSL GSAYQAMILG VDSKNIFNFK VSQEGLKLSN 
DMMGSYAEMK FDHTNSLNIA GLSLDFSSKL DNIYSSDKFY KQTVNLQLQP YSLVTTLNSD 
LKYNALDLTN NGKLRLEPLK LHVAGNLKGA YQNNEIKHIY AISSAALSAS YKADTVAKVQ 
GVEFSHRLNT DIAGLASAID MSTNYNSDSL HFSNVFRSVM APFTMTIDAH TNGNGKLALW 
GEHTGQLYSK FLLKAEPLAF TFSHDYKGST SHHLVSRKSI SAALEHKVSA LLTPAEQTGT 
WKLKTQFNNN EYSQDLDAYN TKDKIGVELT GRTLADLTLL DSPIKVPLLL SEPINIIDAL 
EMRDAVEKPQ EFTIVAFVKY DKNQDVHSIN LPFFETLQEY FERNRQTIIV VLENVQRNLK 
HINIDQFVRK YRAALGKLPQ QANDYLNSFN WERQVSHAKE KLTALTKKYR ITENDIQIAL 
DDAKINFNEK LSQLQTYMIQ FDQYIKDSYD LHDLKIAIAN IIDEIIEKLK SLDEHYHIRV 
NLVKTIHDLH LFIENIDFNK SGSSTASWIQ NVDTKYQIRI QIQEKLQQLK RHIQNIDIQH 
LAGKLKQHIE AIDVRVLLDQ LGTTISFERI NDILEHVKHF VINLIGDFEV AEKINAFRAK 
VHELIERYEV DQQIQVLMDK LVELAHQYKL KETIQKLSNV LQQVKIKDYF EKLVGFIDDA 
VKKLNELSFK TFIEDVNKFL DMLIKKLKSF DYHQFVDETN DKIREVTQRL NGEIQALELP 
QKAEALKLFL EETKATVAVY LESLQDTKIT LIINWLQEAL SSASLAHMKA KFRETLEDTR 
DRMYQMDIQQ ELQRYLSLVG QVYSTLVTYI SDWWTLAAKN LTDFAEQYSI QDWAKRMKAL 
VEQGFTVPEI KTILGTMPAF EVSLQALQKA TFQTPDFIVP LTDLRIPSVQ INFKDLKNIK 
IPSRFSTPEF TILNTFHIPS FTIDFVEMKV KIIRTIDQML NSELQWPVPD IYLRDLKVED 
IPLARITLPD FRLPEIAIPE FIIPTLNLND FQVPDLHIPE FQLPHISHTI EVPTFGKLYS 
ILKIQSPLFT LDANADIGNG TTSANEAGIA ASITAKGESK LEVLNFDFQA NAQLSNPKIN 
PLALKESVKF SSKYLRTEHG SEMLFFGNAI EGKSNTVASL HTEKNTLELS NGVIVKINNQ 
LTLDSNTKYF HKLNIPKLDF SSQADLRNEI KTLLKAGHIA WTSSGKGSWK WACPRFSDEG 
THESQISFTI EGPLTSFGLS NKINSKHLRV NQNLVYESGS LNFSKLEIQS QVDSQHVGHS 
VLTAKGMALF GEGKAEFTGR HDAHLNGKVI GTLKNSLFFS AQPFEITAST NNEGNLKVRF 
PLRLTGKIDF LNNYALFLSP SAQQASWQVS ARFNQYKYNQ NFSAGNNENI MEAHVGINGE 
ANLDFLNIPL TIPEMRLPYT IITTPPLKDF SLWEKTGLKE FLKTTKQSFD LSVKAQYKKN 
KHRHSITNPL AVLCEFISQS IKSFDRHFEK NRNNALDFVT KSYNETKIKF DKYKAEKSHD 
ELPRTFQIPG YTVPVVNVEV SPFTIEMSAF GYVFPKAVSM PSFSILGSDV RVPSYTLILP 
SLELPVLHVP RNLKLSLPDF KELCTISHIF IPAMGNITYD FSFKSSVITL NTNAELFNQS 
DIVAHLLSSS SSVIDALQYK LEGTTRLTRK RGLKLATALS LSNKFVEGSH NSTVSLTTKN 
MEVSVATTTK AQIPILRMNF KQELNGNTKS KPTVSSSMEF KYDFNSSMLY STAKGAVDHK 
LSLESLTSYF SIESSTKGDV KGSVLSREYS GTIASEANTY LNSKSTRSSV KLQGTSKIDD 
IWNLEVKENF AGEATLQRIY SLWEHSTKNH LQLEGLFFTN GEHTSKATLE LSPWQMSALV 
QVHASQPSSF HDFPDLGQEV ALNANTKNQK IRWKNEVRIH SGSFQSQVEL SNDQEKAHLD 
IAGSLEGHLR FLKNIILPVY DKSLWDFLKL DVTTSIGRRQ HLRVSTAFVY TKNPNGYSFS 
IPVKVLADKF IIPGLKLNDL NSVLVMPTFH VPFTDLQVPS CKLDFREIQI YKKLRTSSFA 
LNLPTLPEVK FPEVDVLTKY SQPEDSLIPF FEITVPESQL TVSQFTLPKS VSDGIAALDL 
NAVANKIADF ELPTIIVPEQ TIEIPSIKFS VPAGIVIPSF QALTARFEVD SPVYNATWSA 
SLKNKADYVE TVLDSTCSST VQFLEYELNV LGTHKIEDGT LASKTKGTFA HRDFSAEYEE 
DGKYEGLQEW EGKAHLNIKS PAFTDLHLRY QKDKKGISTS AASPAVGTVG MDMDEDDDFS 
KWNFYYSPQS SPDKKLTIFK TELRVRESDE ETQIKVNWEE EAASGLLTSL KDNVPKATGV 
LYDYVNKYHW EHTGLTLREV SSKLRRNLQN NAEWVYQGAI RQIDDIDVRF QKAASGTTGT 
YQEWKDKAQN LYQELLTQEG QASFQGLKDN VFDGLVRVTQ EFHMKVKHLI DSLIDFLNFP 
RFQFPGKPGI YTREELCTMF IREVGTVLSQ VYSKVHNGSE ILFSYFQDLV ITLPFELRKH 
KLIDVISMYR ELLKDLSKEA QEVFKAIQSL KTTEVLRNLQ DLLQFIFQLI EDNIKQLKEM 
KFTYLINYIQ DEINTIFSDY IPYVFKLLKE NLCLNLHKFN EFIQNELQEA SQELQQIHQY 
IMALREEYFD PSIVGWTVKY YELEEKIVSL IKNLLVALKD FHSEYIVSAS NFTSQLSSQV 
EQFLHRNIQE YLSILTDPDG KGKEKIAELS ATAQEIIKSQ AIATKKIISD YHQQFRYKLQ 
DFSDQLSDYY EKFIAESKRL IDLSIQNYHT FLIYITELLK KLQSTTVMNP YMKLAPGELT 
IIL

Genular Protein ID: 90469586

Symbol: Q59HB3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59HB3

Database IDs:

ARBA 10 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 1 SUPFAM 1

Sequence Information:

  • Length: 1615
  • Mass: 183579
  • Checksum: D3F95D589D0927FD
  • Sequence:
    • TIEGPLTSFG LSNKINSKHL RVNQNLVYES GSLNFSKLEI QSQVDSQHVG HSVLTAKGMA 
LFGEGKAEFT GRHDAHLNGK VIGTLKNSLF FSAQPFEITA STNNEGNLKV RFPLRLTGKI 
DFLNNYALFL SPSAQQASWQ VSARFNQYKY NQNFSAGNNE NIMEAHVGIN GEANLDFLNI 
PLTIPEMRLP YTIITTPPLK DFSLWEKTGL KEFLKTTKQS FDLSVKAQYK KNKHRHSITN 
PLAVLCEFIS QSIKSFDRHF EKNRNNALDF VTKSYNETKI KFDKYKAEKS HDELPRTFQI 
PGYTVPVVNV EVSPFTIEMS AFGYVFPKAV SMPSFSILGS DVRVPSYTLI LPSLELPVLH 
VPRNLKLSLP DFKELCTISH IFIPAMGNIT YDFSFKSSVI TLNTNAELFN QSDIVAHLLS 
SSSSVIDALQ YKLEGTTRLT RKRGLKLATA LSLSNKFVEG SHNSTVSLTT KNMEVSVATT 
TKAQIPILRM NFKQELNGNT KSKPTVSSSM EFKYDFNSSM LYSTAKGAVD HKLSLESLTS 
YFSIESSTKG DVKGSVLSRE YSGTIASEAN TYLNSKSTRS SVKLQGTSKI DDIWNLEVKE 
NFAGEATLQR IYSLWEHSTK NHLQLEGLFF TNGEHTSKAT LELSPWQMSA LVQVHASQPS 
SFHDFPDLGQ EVALNANTKN QKIRWKNEVR IHSGSFQSQV ELSNDQEKAH LDIAGSLEGH 
LRFLKNIILP VYDKSLWDFL KLDVTTSIGR RQHLRVSTAF VYTKNPNGYS FSIPVKVLAD 
KFIIPGLKLN DLNSVLVMPT FHVPFTDLQV PSCKLDFREI QIYKKLRTSS FALNLPTLPE 
VKFPEVDVLT KYSQPEDSLI PFFEITVPES QLTVSQFTLP KSVSDGIAAL DLNAVANKIA 
DFELPTIIVP EQTIEIPSIK FSVPAGIVIP SFQALTARFE VDSPVYNATW SASLKNKADY 
VETVLDSTCS STVQFLEYEL NVLGTHKIED GTLASKTKGT FAHRDFSAEY EEDGKYEGLQ 
EWEGKAHLNI KSPAFTDLHL RYQKDKKGIS TSAASPAVGT VGMDMDEDDD FSKWNFYYSP 
QSSPDKKLTI FKTELRVRES DEETQIKVNW EEEAASGLLT SLKDNVPKAT GVLYDYVNKY 
HWEHTGLTLR EVSSKLRRNL QNNAEWVYQG AIRQIDDIDV RFQKAASGTT GTYQEWKDKA 
QNLYQELLTQ EGQASFQGLK DNVFDGLVRV TQEFHMKVKH LIDSLIDFLN FPRFQFPGKP 
GIYTREELCT MFIREVGTVL SQVYSKVHNG SEILFSYFQD LVITLPFELR KHKLIDVISM 
YRELLKDLSK EAQEVFKAIQ SLKTTEVLRN LQDLLQFIFQ LIEDNIKQLK EMKFTYLINY 
IQDEINTIFS DYIPYVFKLL KENLCLNLHK FNEFIQNELQ EASQELQQIH QYIMALREEY 
FDPSIVGWTV KYYELEEKIV SLIKNLLVAL KDFHSEYIVS ASNFTSQLSS QVEQFLHRNI 
QEYLSILTDP DGKGKEKIAE LSATAQEIIK SQTIATKKII SDYHQQFRYK LQDFSDQLSD 
YYEKFIAESK RLIDLSIQNY HTFLIYITEL LKKLQSTTVM NPYMKLAPGE LTIIL

Genular Protein ID: 3578240559

Symbol: Q7Z7Q0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q7Z7Q0

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 7 Gene3D 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 1 SMART 2 SMR 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 825
  • Mass: 92334
  • Checksum: 9004A128F9E6338E
  • Sequence:
    • MDPPRPALLA LPALLLLLLA GARAEEEMLE NVSLVCPKDA TRFKHLRKYT YNYEAESSSG 
VPGTADSRSA TRINCKVELE VPQLCSFILK TSQCILKEVY GFNPEGKALL KKTKNSEEFA 
AAMSRYELKL AIPEGKQVFL YPEKDEPTYI LNIKRGIISA LLVPPETEEA KQVLFLDTVY 
GNCSTHFTVK TRKGNVATEI STERDLGQCD RFKPIRTGIS PLALIKGMTR PLSTLISSSQ 
SCQYTLDAKR KHVAEAICKE QHLFLPFSYK NKYGMVAQVT QTLKLEDTPK INSRFFGEGT 
KKMGLAFEST KSTSPPKQAE AVLKTLQELK KLTISEQNIQ RANLFNKLVT ELRGLSDEAV 
TSLLPQLIEV SSPITLQALV QCGQPQCSTH ILQWLKRVHA NPLLIDVVTY LVALIPEPSA 
QQLREIFNMA RDQRSRATLY ALSHAVNNYH KTNPTGTQEL LDIANYLMEQ IQDDCTGDED 
YTYLILRVIG NMGQTMEQLT PELKSSILKC VQSTKPSLMI QKAAIQALRK MEPKDKDQEV 
LLQTFLDDAS PGDKRLAAYL MLMRSPSQAD INKIVQILPW EQNEQVKNFV ASHIANILNS 
EELDIQDLKK LVKEALKESQ LPTVMDFRKF SRNYQLYKSV SLPSLDPASA KIEGNLIFDP 
NNYLPKESML KTTLTAFGFA SADLIEIGLE GKGFEPTLEA LFGKQGFFPD SVNKALYWVN 
GQVPDGVSKV LVDHFGYTKD DKHEQDMVNG IMLSVEKLIK DLKSKEVPEA RAYLRILGEE 
LGFASLHDLQ LLGKLLLMDR PDSLTIPAAQ ARKDACTFFR DGGLP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.