eIF4A | FBgn0001942 | NCBI 33835

Details for: eIF4A

Gene ID: 33835

Symbol: eIF4A

Ensembl ID: FBgn0001942

Description: eukaryotic translation initiation factor 4A

Associated with

Activation of the mrna upon binding of the cap-binding complex and eifs, and subsequent binding to 43s
(R-DME-72662)
Antiviral mechanism by ifn-stimulated genes
(R-DME-1169410)
Cap-dependent translation initiation
(R-DME-72737)
Cytokine signaling in immune system
(R-DME-1280215)
Eukaryotic translation initiation
(R-DME-72613)
Immune system
(R-DME-168256)
Interferon signaling
(R-DME-913531)
Isg15 antiviral mechanism
(R-DME-1169408)
L13a-mediated translational silencing of ceruloplasmin expression
(R-DME-156827)
Metabolism of proteins
(R-DME-392499)
Ribosomal scanning and start codon recognition
(R-DME-72702)
Translation
(R-DME-72766)
Translation initiation complex formation
(R-DME-72649)
Atp binding
(GO:0005524)
Cytoplasmic stress granule
(GO:0010494)
Cytoplasmic translational initiation
(GO:0002183)
Cytosol
(GO:0005829)
Eukaryotic translation initiation factor 4f complex
(GO:0016281)
Female germ-line stem cell asymmetric division
(GO:0048132)
Germ-line stem cell population maintenance
(GO:0030718)
Mitotic cell cycle
(GO:0000278)
Negative regulation of bmp signaling pathway
(GO:0030514)
Nucleic acid binding
(GO:0003676)
Nucleus
(GO:0005634)
Oogenesis
(GO:0048477)
P granule
(GO:0043186)
Pole cell formation
(GO:0007279)
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process
(GO:0032436)
Regulation of alternative mrna splicing, via spliceosome
(GO:0000381)
Rna helicase activity
(GO:0003724)
Smad binding
(GO:0046332)
Translational initiation
(GO:0006413)
Translation initiation factor activity
(GO:0003743)

Other Information

Proteins

Eukaryotic initiation factor 4A

Genular Protein ID: 224856293

Symbol: IF4A_DROME

Name: Eukaryotic initiation factor 4A

UniProtKB Accession Codes:

Q02748 A4UZV9 Q9U9Y6 Q9VMJ8

Database IDs:

Citations:

PubMed ID: 8455559

Title: Identification of an essential Drosophila gene that is homologous to the translation initiation factor eIF-4A of yeast and mouse.

PubMed ID: 8455559

DOI: 10.1007/bf00282805

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 10731138

Title: A Drosophila complementary DNA resource.

PubMed ID: 10731138

DOI: 10.1126/science.287.5461.2222

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 18590813

Title: Isolation of new polar granule components in Drosophila reveals P body and ER associated proteins.

PubMed ID: 18590813

DOI: 10.1016/j.mod.2008.06.005

Sequence Information:

Length: 403
Mass: 45879
Checksum: B870FF8C420CC4F2
Sequence:

MDDRNEIPQD GPASMEPEGV IESTWHEVYD NFDDMNLREE LLRGIYGYGF EKPSAIQQRA 
IIPCVRGRDV IAQAQSGTGK TATFSIAILQ QIDTSIRECQ ALILAPTREL ATQIQRVVMA 
LGEYMKVHSH ACIGGTNVRE DARILESGCH VVVGTPGRVY DMINRKVLRT QYIKLFVLDE 
ADEMLSRGFK DQIQDVFKML PPDVQVILLS ATMPPDVLEV SRCFMRDPVS ILVKKEELTL 
EGIKQFYVNV KQENWKLGTL CDLYDTLSIT QSVIFCNTRR KVDQLTQEMS IHNFTVSAMH 
GDMEQRDREV IMKQFRSGSS RVLITTDLLA RGIDVQQVSL VINYDLPSNR ENYIHRIGRG 
GRFGRKGVAI NFITDDDRRI LKDIEQFYHT TIEEMPANIA DLI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: eIF4A

Associated with

Other Information

Identification of an essential Drosophila gene that is homologous to the translation initiation factor eIF-4A of yeast and mouse. PubMed ID: 8455559

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila complementary DNA resource. PubMed ID: 10731138

A Drosophila full-length cDNA resource. PubMed ID: 12537569