Fic | FBgn0263278 | NCBI 33897

Details for: Fic

Gene ID: 33897

Symbol: Fic

Ensembl ID: FBgn0263278

Description: Fic domain-containing protein

Associated with

Ampylase activity
(GO:0070733)
Detection of light stimulus involved in visual perception
(GO:0050908)
Histamine transport
(GO:0051608)
Hsp70 protein binding
(GO:0030544)
Plasma membrane
(GO:0005886)
Protein-folding chaperone binding
(GO:0051087)
Protein adenylylation
(GO:0018117)
Protein adenylylhydrolase activity
(GO:0044603)
Protein deadenylylation
(GO:0044602)
Protein homodimerization activity
(GO:0042803)
Response to endoplasmic reticulum stress
(GO:0034976)
Visual behavior
(GO:0007632)

Other Information

Proteins

Protein adenylyltransferase Fic

Genular Protein ID: 3383345457

Symbol: FICD_DROME

Name: Protein adenylyltransferase Fic

UniProtKB Accession Codes:

Q8SWV6 Q9VMD8

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 19503829

Title: Fido, a novel AMPylation domain common to fic, doc, and AvrB.

PubMed ID: 19503829

DOI: 10.1371/journal.pone.0005818

PubMed ID: 25395623

Title: Unfolded protein response-regulated Drosophila Fic (dFic) protein reversibly AMPylates BiP chaperone during endoplasmic reticulum homeostasis.

PubMed ID: 25395623

DOI: 10.1074/jbc.m114.612515

PubMed ID: 29089387

Title: Fic-mediated deAMPylation is not dependent on homodimerization and rescues toxic AMPylation in flies.

PubMed ID: 29089387

DOI: 10.1074/jbc.m117.799296

Sequence Information:

Length: 492
Mass: 55725
Checksum: 452412D2865FED3A
Sequence:

MGTEAEQPSP PAQQQDQENP PLCKAQNPKP ARLYRFVLIF VAGSLAAWTF HALSSTNLVW 
KLRQLHHLPT AHYLQTRDEF ALYSVEELNA FKEFYDKSVS DSVGASYTEA EQTNIKEALG 
ALRMAQDLYL AGKDDKAARL FEHALALAPR HPEVLLRYGE FLEHNQRNIV LADQYYFQAL 
TISPSNSEAL ANRQRTADVV QSLDERRLES LDSKRDALSA IHESNGALRR AKKEAYFQHI 
YHSVGIEGNT MTLAQTRSIL ETRMAVDGKS IDEHNEILGM DLAMKYINAS LVQKIDITIK 
DILELHRRVL GHVDPIEGGE FRRNQVYVGG HIPPGPGDLA LLMQRFERWL NSEHSSTLHP 
VNYAALAHYK LVHIHPFVDG NGRTSRLLMN TLLMRAGYPP VIIPKQQRSK YYHFLKLANE 
GDIRPFVRFI ADCTEKTLDL YLWATSDLPQ QIPMLIQTES EAGERLAQMQ SPNVAQRSSI 
LEFYESGSGD LP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fic

Associated with

Other Information

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila full-length cDNA resource. PubMed ID: 12537569

Fido, a novel AMPylation domain common to fic, doc, and AvrB. PubMed ID: 19503829

Unfolded protein response-regulated Drosophila Fic (dFic) protein reversibly AMPylates BiP chaperone during endoplasmic reticulum homeostasis. PubMed ID: 25395623