Associated with
Other Information
Genular Protein ID: 3303879260
Symbol: CUP_DROME
Name: Protein cup
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9118812
Title: The Drosophila gene fs(2)cup interacts with otu to define a cytoplasmic pathway required for the structure and function of germ-line chromosomes.
PubMed ID: 9118812
PubMed ID: 10731132
Title: The genome sequence of Drosophila melanogaster.
PubMed ID: 10731132
PubMed ID: 12537572
Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.
PubMed ID: 12537572
PubMed ID: 12537569
Title: A Drosophila full-length cDNA resource.
PubMed ID: 12537569
PubMed ID: 11060247
Title: Nanos interacts with cup in the female germline of Drosophila.
PubMed ID: 11060247
PubMed ID: 10662770
Title: Isolation of a ribonucleoprotein complex involved in mRNA localization in Drosophila oocytes.
PubMed ID: 10662770
PubMed ID: 14691132
Title: Cup is an eIF4E binding protein required for both the translational repression of oskar and the recruitment of Barentsz.
PubMed ID: 14691132
PubMed ID: 14723848
Title: Drosophila Cup is an eIF4E binding protein that associates with Bruno and regulates oskar mRNA translation in oogenesis.
PubMed ID: 14723848
PubMed ID: 14685270
Title: Drosophila Cup is an eIF4E-binding protein that functions in Smaug-mediated translational repression.
PubMed ID: 14685270
PubMed ID: 15465908
Title: Cup is a nucleocytoplasmic shuttling protein that interacts with the eukaryotic translation initiation factor 4E to modulate Drosophila ovary development.
PubMed ID: 15465908
PubMed ID: 17178403
Title: Staufen- and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P bodies.
PubMed ID: 17178403
PubMed ID: 17277377
Title: nup154 genetically interacts with cup and plays a cell-type-specific function during Drosophila melanogaster egg-chamber development.
PubMed ID: 17277377
PubMed ID: 18327897
Title: Phosphoproteome analysis of Drosophila melanogaster embryos.
PubMed ID: 18327897
DOI: 10.1021/pr700696a
PubMed ID: 21081899
Title: Smaug assembles an ATP-dependent stable complex repressing nanos mRNA translation at multiple levels.
PubMed ID: 21081899
PubMed ID: 21937713
Title: CUP promotes deadenylation and inhibits decapping of mRNA targets.
PubMed ID: 21937713
DOI: 10.1101/gad.17136311
PubMed ID: 22164257
Title: Cup blocks the precocious activation of the orb autoregulatory loop.
PubMed ID: 22164257
PubMed ID: 22454519
Title: The translational repressor Cup is required for germ cell development in Drosophila.
PubMed ID: 22454519
DOI: 10.1242/jcs.095208
PubMed ID: 24335285
Title: Human 4E-T represses translation of bound mRNAs and enhances microRNA-mediated silencing.
PubMed ID: 24335285
DOI: 10.1093/nar/gkt1265
PubMed ID: 28875934
Title: ME31B globally represses maternal mRNAs by two distinct mechanisms during the Drosophila maternal-to-zygotic transition.
PubMed ID: 28875934
DOI: 10.7554/elife.27891
PubMed ID: 22832024
Title: Crystal structure of a minimal eIF4E-Cup complex reveals a general mechanism of eIF4E regulation in translational repression.
PubMed ID: 22832024
Sequence Information:
- Length: 1117
- Mass: 125672
- Checksum: 91274997F199EFD3
- Sequence:
MQMAEAEQEN GAGALKIATN AGATDRPAHQ QLPLPVEDQQ DEVLTPAEKG KFEYPPPPPP PTPVQAPLAT KATALNASQE HDDDEANSEK WEDPCAPPPP PPLPTSAFLA TGLGYLKLPA FKLKDALEKA ITKLEANKRT LKASPESSRS IKNKNVVALE MLPRRSNPET IGDGSMLAST STAVMLQTKK PAVIVEMERR CKIINLLAKQ NQILESISGE AIPMHGPSKH LHEDEGLTLQ VLSARASTPY TQPSSMLSCT AVSCDLEHDS PRKQVASKEA VPEQQSSQVQ QKRPPSTGIH KPGSLRAPKA VRPTTAPVVS SKPVKSYTRS RLMDIRNGMF NALMHRSKES FVMPRIATCD DIELEGRLRR MNIWRTSDGT RFRTRSTTAN LNMNNNNNNE CMPAFFKNKN KPNLISDESI IQSQPPQPQT EFQDPAIVNQ RRIGSGRLNH SKWGYNDEDY HSYHNGKSQH MEEVNSKNSK NMTVLQFFDN GEISSQPQRR PNTPVMGMSI NRSENDTLHS NESSEDLSRA NENYVKRVMS GFLVVSKPKS RDVEDRHHRR YRNQNEEPEW FSCGPTSRLD TIELCGFDED EEKMLKEGNK NHGLGETERE TSKQKMDHKY KWTHAEPMGR SKYMPKHDTN NNHNVENMNN VMATEHQQQK EEKRPGSGRS FQFDKFNQSQ QNYESSSYVN HQQPPQTQPQ QMQQQSNTNT NNSKFMSFFA NEGNSSSSSL NEFFKQAINQ GHGNNPEQPK SLGHIGQMPS VDQLEAKWRR NSLNNVGETA NKQTDNFQKL IGSLSSAKPQ SQAVGYDAIS NFIMQQQQYQ QQQQKQHLII QQQQQHTAFL ASLQLKAILG RADTQLLLLR LTKGEISKHG LLVQLANPRL TDMDREAITA VLQFTNTQQQ QQQHKQQLDM LSSTVIASQL QNLHNLAIVQ QTLAARQQPQ HNPQTQAPHQ LSQEDLQAHA NVIMRNAVMK RKIEEQTSKL INGGAKHQAQ QQYLNRGQQR QARPDANSNA LLHALISGGG NNHASGYPMN GQPQKHHSNL RFGDNQNFQS FESNQPHFAT QYKQQYQQSQ QQHPHQQPQQ LNSLHQNNAG AVNSFNKAQM QAQSAISMLP NSGDEFH
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.