Su var 205 | FBgn0003607 | NCBI 34119

Details for: Su var 205

Gene ID: 34119

Symbol: Su var 205

Ensembl ID: FBgn0003607

Description: Suppressor of variegation 205

Associated with

Chromatin binding
(GO:0003682)
Chromatin organization
(GO:0006325)
Chromocenter
(GO:0010369)
Chromosome
(GO:0005694)
Chromosome, centromeric region
(GO:0000775)
Chromosome, telomeric region
(GO:0000781)
Chromosome organization
(GO:0051276)
Condensed chromosome
(GO:0000793)
Condensed chromosome, centromeric region
(GO:0000779)
Euchromatin
(GO:0000791)
Heterochromatin
(GO:0000792)
Heterochromatin formation
(GO:0031507)
Histone binding
(GO:0042393)
Hsp70 protein binding
(GO:0030544)
Methylated histone binding
(GO:0035064)
Mitotic cell cycle
(GO:0000278)
Mrna binding
(GO:0003729)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleus
(GO:0005634)
Pericentric heterochromatin
(GO:0005721)
Pericentric heterochromatin formation
(GO:0031508)
Polytene chromosome
(GO:0005700)
Polytene chromosome chromocenter
(GO:0005701)
Polytene chromosome interband
(GO:0005705)
Polytene chromosome puff
(GO:0005703)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of dna methylation-dependent heterochromatin formation
(GO:0090309)
Positive regulation of fact complex assembly
(GO:1905646)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein-containing complex binding
(GO:0044877)
Protein-macromolecule adaptor activity
(GO:0030674)
Protein binding
(GO:0005515)
Protein localization to euchromatin
(GO:1905632)
Rdna binding
(GO:0000182)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of protein localization to chromatin
(GO:1905634)
Rna binding
(GO:0003723)
Rna polymerase binding
(GO:0070063)
Rna polymerase ii c-terminal domain binding
(GO:0099122)
Satellite dna binding
(GO:0003696)
Telomere maintenance
(GO:0000723)

Other Information

Proteins

Heterochromatin protein 1

Genular Protein ID: 2793014044

Symbol: HP1_DROME

Name: Heterochromatin protein 1

UniProtKB Accession Codes:

P05205 A4V0F1 B6UVR4 B6UVS1 B6UVS2 B6UVS3 B6UVT2 B6UVT6 B6UVT7 Q9VLR6

Database IDs:

Citations:

PubMed ID: 3099166

Title: Identification of a nonhistone chromosomal protein associated with heterochromatin in Drosophila melanogaster and its gene.

PubMed ID: 3099166

DOI: 10.1128/mcb.6.11.3862-3872.1986

PubMed ID: 2124708

Title: Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster.

PubMed ID: 2124708

DOI: 10.1073/pnas.87.24.9923

PubMed ID: 18984573

Title: Molecular population genetics and evolution of Drosophila meiosis genes.

PubMed ID: 18984573

DOI: 10.1534/genetics.108.093807

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 1708124

Title: A sequence motif found in a Drosophila heterochromatin protein is conserved in animals and plants.

PubMed ID: 1708124

DOI: 10.1093/nar/19.4.789

PubMed ID: 9378752

Title: An actin-related protein in Drosophila colocalizes with heterochromatin protein 1 in pericentric heterochromatin.

PubMed ID: 9378752

DOI: 10.1242/jcs.110.17.1999

PubMed ID: 11566886

Title: Specificity of the HP1 chromo domain for the methylated N-terminus of histone H3.

PubMed ID: 11566886

DOI: 10.1093/emboj/20.18.5232

PubMed ID: 11867540

Title: Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing.

PubMed ID: 11867540

DOI: 10.1093/emboj/21.5.1121

PubMed ID: 12808023

Title: Drosophila MCM10 interacts with members of the prereplication complex and is required for proper chromosome condensation.

PubMed ID: 12808023

DOI: 10.1091/mbc.e02-11-0706

PubMed ID: 17875665

Title: Drosophila PIWI associates with chromatin and interacts directly with HP1a.

PubMed ID: 17875665

DOI: 10.1101/gad.1564307

PubMed ID: 17372656

Title: An integrated chemical, mass spectrometric and computational strategy for (quantitative) phosphoproteomics: application to Drosophila melanogaster Kc167 cells.

PubMed ID: 17372656

DOI: 10.1039/b617545g

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

PubMed ID: 26389589

Title: An Interaction between RRP6 and SU(VAR)3-9 Targets RRP6 to Heterochromatin and Contributes to Heterochromatin Maintenance in Drosophila melanogaster.

PubMed ID: 26389589

DOI: 10.1371/journal.pgen.1005523

PubMed ID: 11859155

Title: Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail.

PubMed ID: 11859155

DOI: 10.1126/science.1069473

Sequence Information:

Length: 206
Mass: 23185
Checksum: 6A5B204C487526B7
Sequence:

MGKKIDNPES SAKVSDAEEE EEEYAVEKII DRRVRKGKVE YYLKWKGYPE TENTWEPENN 
LDCQDLIQQY EASRKDEEKS AASKKDRPSS SAKAKETQGR ASSSTSTASK RKSEEPTAPS 
GNKSKRTTDA EQDTIPVSGS TGFDRGLEAE KILGASDNNG RLTFLIQFKG VDQAEMVPSS 
VANEKIPRMV IHFYEERLSW YSDNED

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Su var 205

Associated with

Other Information

Identification of a nonhistone chromosomal protein associated with heterochromatin in Drosophila melanogaster and its gene. PubMed ID: 3099166

Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster. PubMed ID: 2124708

Molecular population genetics and evolution of Drosophila meiosis genes. PubMed ID: 18984573

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila full-length cDNA resource. PubMed ID: 12537569

A sequence motif found in a Drosophila heterochromatin protein is conserved in animals and plants. PubMed ID: 1708124

An actin-related protein in Drosophila colocalizes with heterochromatin protein 1 in pericentric heterochromatin. PubMed ID: 9378752

Specificity of the HP1 chromo domain for the methylated N-terminus of histone H3. PubMed ID: 11566886

Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing. PubMed ID: 11867540

Drosophila MCM10 interacts with members of the prereplication complex and is required for proper chromosome condensation. PubMed ID: 12808023

Drosophila PIWI associates with chromatin and interacts directly with HP1a. PubMed ID: 17875665

An integrated chemical, mass spectrometric and computational strategy for (quantitative) phosphoproteomics: application to Drosophila melanogaster Kc167 cells. PubMed ID: 17372656

Phosphoproteome analysis of Drosophila melanogaster embryos. PubMed ID: 18327897

An Interaction between RRP6 and SU(VAR)3-9 Targets RRP6 to Heterochromatin and Contributes to Heterochromatin Maintenance in Drosophila melanogaster. PubMed ID: 26389589

Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail. PubMed ID: 11859155