Details for: grk

Gene ID: 34171

Symbol: grk

Ensembl ID: FBgn0001137

Description: gurken

Associated with

  • Anterior/posterior axis specification, follicular epithelium
    (GO:0030714)
  • Anterior/posterior pattern specification
    (GO:0009952)
  • Cell surface receptor signaling pathway
    (GO:0007166)
  • Chorion-containing eggshell pattern formation
    (GO:0030381)
  • Determination of dorsal identity
    (GO:0048263)
  • Dorsal/ventral axis specification, ovarian follicular epithelium
    (GO:0008069)
  • Dorsal appendage formation
    (GO:0046843)
  • Epidermal growth factor receptor binding
    (GO:0005154)
  • Epidermal growth factor receptor signaling pathway
    (GO:0007173)
  • Extracellular space
    (GO:0005615)
  • Imaginal disc-derived wing vein specification
    (GO:0007474)
  • Maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded
    (GO:0008070)
  • Oocyte anterior/posterior axis specification
    (GO:0007314)
  • Oocyte dorsal/ventral axis specification
    (GO:0007310)
  • Oocyte microtubule cytoskeleton organization
    (GO:0016325)
  • Plasma membrane
    (GO:0005886)
  • Positive regulation of border follicle cell migration
    (GO:1903688)
  • Protein binding
    (GO:0005515)
  • Receptor ligand activity
    (GO:0048018)

Other Information

Genular Protein ID: 738930543

Symbol: GRK_DROME

Name: Protein gurken

UniProtKB Accession Codes:

P42287 Q9VLL2

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CTD 1 DIP 1 DNASU 1 EMBL 4 EnsemblMetazoa 1 EvolutionaryTrace 1 FlyBase 1 GO 18 Gene3D 1 GeneTree 1 GenomeRNAi 1 GlyCosmos 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 5 PIR 1 PRO 1 PROSITE 2 PaxDb 1 PhylomeDB 1 Proteomes 1 RefSeq 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 7691414

Title: The Drosophila dorsoventral patterning gene gurken produces a dorsally localized RNA and encodes a TGF alpha-like protein.

PubMed ID: 7691414

DOI: 10.1016/s0092-8674(05)80093-5

PubMed ID: 10790337

Title: Localization of gurken RNA in Drosophila oogenesis requires elements in the 5' and 3' regions of the transcript.

PubMed ID: 10790337

DOI: 10.1006/dbio.2000.9690

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 16396907

Title: Drosophila Cornichon acts as cargo receptor for ER export of the TGFalpha-like growth factor Gurken.

PubMed ID: 16396907

DOI: 10.1242/dev.02219

Sequence Information:

  • Length: 295
  • Mass: 33280
  • Checksum: 80E993704DE3123B
  • Sequence:
    • MMQIPFTRIF KVIFVLSTIV AVTDCCSSRI LLLREHTLKI VQHQHSHMHE HAHELQQQIQ 
ETAVELLNRL ELQRKQLEAS AQEEADQLHP DTDPNPDSGG QLPNADDSIA ADPEQDGIIL 
GSSTDTWLAS ESSTPITDSE TVTTPETVTH TGEPPPDPSS SSTPDSTTPS PNDKETEIQM 
LPCSEAYNTS FCLNGGHCFQ HPMVNNTVFH SCLCVNDYDG ERCAYKSWNG DYIYSPPTAQ 
RKVRMAHIVF SFPVLLMLSS LYVLFAAVFM LRNVPDYRRK QQQLHLHKQR FFVRC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.