Details for: mtDNA helicase

Gene ID: 34307

Symbol: mtDNA helicase

Ensembl ID: FBgn0032154

Description: mitochondrial DNA helicase

Associated with

Other Information

Genular Protein ID: 1786247718

Symbol: PEO1_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 17272269

Title: Differential phenotypes of active site and human autosomal dominant progressive external ophthalmoplegia mutations in Drosophila mitochondrial DNA helicase expressed in Schneider cells.

PubMed ID: 17272269

DOI: 10.1074/jbc.m610550200

PubMed ID: 19063859

Title: Functional importance of the conserved N-terminal domain of the mitochondrial replicative DNA helicase.

PubMed ID: 19063859

DOI: 10.1016/j.bbabio.2008.11.005

PubMed ID: 22952820

Title: Modeling pathogenic mutations of human twinkle in Drosophila suggests an apoptosis role in response to mitochondrial defects.

PubMed ID: 22952820

DOI: 10.1371/journal.pone.0043954

PubMed ID: 25023283

Title: The N-terminal domain of the Drosophila mitochondrial replicative DNA helicase contains an iron-sulfur cluster and binds DNA.

PubMed ID: 25023283

DOI: 10.1074/jbc.m114.587774

PubMed ID: 34950192

Title: Implications of Membrane Binding by the Fe-S Cluster-Containing N-Terminal Domain in the Drosophila Mitochondrial Replicative DNA Helicase.

PubMed ID: 34950192

DOI: 10.3389/fgene.2021.790521

Sequence Information:

  • Length: 613
  • Mass: 70068
  • Checksum: 289E551726900436
  • Sequence:
  • MRRAGLIKPL LRINNEKQRV WRKNYATQVV SGLEECSLDP KEYVDFKRQL RQLNLPHKDG 
    HTCLQLECRL CDRNRQPVTN AQKGTDHGLL AYVNKRTGAF ICPNCDVKTS LTSALLSYQL 
    PKPVGYKQPL QRQPVYESRF PHLAVVTPEA CAALGIKGLK EDQLNAIGAQ WEPQQQLLHF 
    KLRNAAQVEV GEKVLYLGDR REEIFQSSSS SGLLIHGAMN KTKAVLVSNL IDFIVLATQN 
    IETHCVVCLP YELKTLPQEC LPALERFKEL IFWLHYDASH SWDAARAFAL KLDERRCLLI 
    RPTETEPAPH LALRRRLNLR HILAKATPVQ HKAITTFGAM RNDILSELQN IEKVNGVKWK 
    RFPVLNKLLK GHRRGELTIL TGPTGSGKTT FMSEYSLDLA MQGVNTLWGS FEIRNTRLAA 
    TLLRQYVGYP LDDRLHEFNH WAAEFERLPL YFMTFHGQQP LKPVLEAIEH ASYVHDVMHV 
    IIDNLQFMMG VSTFRGDKFF EQDSIIAAFR SFATKHNVHV TLVMHPRKER QEDELTTSSV 
    FGTAKATQEA DNVLIIQDKR LTSVRGKKYL QIAKNRYSGD LGIMPLEFDK DGLSYSTQIQ 
    NAKRKREKTP SEN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.