Details for: me31B

Gene ID: 34364

Symbol: me31B

Ensembl ID: FBgn0004419

Description: maternal expression at 31B

Associated with

Other Information

Genular Protein ID: 1179391664

Symbol: DDX6_DROME

Name: ATP-dependent RNA helicase me31b

UniProtKB Accession Codes:

P23128 Q8IPC9 Q961D2 Q9VL17

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 6 ChiTaRS 1 DNASU 1 EC 2 EMBL 4 EnsemblMetazoa 2 FlyBase 1 GO 34 Gene3D 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MINT 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 1 PIR 1 PRO 1 PROSITE 4 PROSITE-ProRule 3 PaxDb 1 Pfam 2 PhylomeDB 1 Proteomes 1 Reactome 1 RefSeq 2 Rhea 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 1900936

Title: A second maternally expressed Drosophila gene encodes a putative RNA helicase of the 'DEAD box' family.

PubMed ID: 1900936

DOI: 10.1073/pnas.88.6.2113

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 10662770

Title: Isolation of a ribonucleoprotein complex involved in mRNA localization in Drosophila oocytes.

PubMed ID: 10662770

DOI: 10.1083/jcb.148.3.427

PubMed ID: 11546740

Title: Me31B silences translation of oocyte-localizing RNAs through the formation of cytoplasmic RNP complex during Drosophila oogenesis.

PubMed ID: 11546740

DOI: 10.1242/dev.128.17.3233

PubMed ID: 16256742

Title: Efficient protein trafficking requires trailer hitch, a component of a ribonucleoprotein complex localized to the ER in Drosophila.

PubMed ID: 16256742

DOI: 10.1016/j.devcel.2005.09.015

PubMed ID: 17178403

Title: Staufen- and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P bodies.

PubMed ID: 17178403

DOI: 10.1016/j.neuron.2006.10.028

PubMed ID: 17982591

Title: P-body components, microRNA regulation, and synaptic plasticity.

PubMed ID: 17982591

DOI: 10.1100/tsw.2007.206

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

PubMed ID: 18765641

Title: Similar modes of interaction enable Trailer Hitch and EDC3 to associate with DCP1 and Me31B in distinct protein complexes.

PubMed ID: 18765641

DOI: 10.1128/mcb.00759-08

PubMed ID: 18590813

Title: Isolation of new polar granule components in Drosophila reveals P body and ER associated proteins.

PubMed ID: 18590813

DOI: 10.1016/j.mod.2008.06.005

PubMed ID: 19285948

Title: Structural basis for the mutually exclusive anchoring of P body components EDC3 and Tral to the DEAD box protein DDX6/Me31B.

PubMed ID: 19285948

DOI: 10.1016/j.molcel.2009.02.014

PubMed ID: 21267420

Title: The Me31B DEAD-Box Helicase Localizes to Postsynaptic Foci and Regulates Expression of a CaMKII Reporter mRNA in Dendrites of Drosophila Olfactory Projection Neurons.

PubMed ID: 21267420

DOI: 10.3389/fncir.2010.00121

PubMed ID: 21447556

Title: PAPI, a novel TUDOR-domain protein, complexes with AGO3, ME31B and TRAL in the nuage to silence transposition.

PubMed ID: 21447556

DOI: 10.1242/dev.059287

PubMed ID: 21081899

Title: Smaug assembles an ATP-dependent stable complex repressing nanos mRNA translation at multiple levels.

PubMed ID: 21081899

DOI: 10.1038/emboj.2010.283

PubMed ID: 28875934

Title: ME31B globally represses maternal mRNAs by two distinct mechanisms during the Drosophila maternal-to-zygotic transition.

PubMed ID: 28875934

DOI: 10.7554/elife.27891

PubMed ID: 28945271

Title: An in vivo proteomic analysis of the Me31B interactome in Drosophila germ granules.

PubMed ID: 28945271

DOI: 10.1002/1873-3468.12854

PubMed ID: 28388438

Title: LSM12 and ME31B/DDX6 Define Distinct Modes of Posttranscriptional Regulation by ATAXIN-2 Protein Complex in Drosophila Circadian Pacemaker Neurons.

PubMed ID: 28388438

DOI: 10.1016/j.molcel.2017.03.004

PubMed ID: 31114929

Title: Direct role for the Drosophila GIGYF protein in 4EHP-mediated mRNA repression.

PubMed ID: 31114929

DOI: 10.1093/nar/gkz429

PubMed ID: 31439631

Title: Molecular basis for GIGYF-Me31B complex assembly in 4EHP-mediated translational repression.

PubMed ID: 31439631

DOI: 10.1101/gad.329219.119

Sequence Information:

  • Length: 459
  • Mass: 51945
  • Checksum: B783E8185EF11E86
  • Sequence:
    • MMTEKLNSGH TNLTSKGIIN DLQIAGNTSD DMGWKSKLKL PPKDNRFKTT DVTDTRGNEF 
EEFCLKRELL MGIFEKGWER PSPIQEAAIP IALSGKDVLA RAKNGTGKTG AYCIPVLEQI 
DPTKDYIQAL VMVPTRELAL QTSQICIELA KHLDIRVMVT TGGTILKDDI LRIYQKVQLI 
IATPGRILDL MDKKVADMSH CRILVLDEAD KLLSLDFQGM LDHVILKLPK DPQILLFSAT 
FPLTVKNFME KHLREPYEIN LMEELTLKGV TQYYAFVQER QKVHCLNTLF SKLQINQSII 
FCNSTQRVEL LAKKITELGY CCYYIHAKMA QAHRNRVFHD FRQGLCRNLV CSDLFTRGID 
VQAVNVVINF DFPRMAETYL HRIGRSGRFG HLGIAINLIT YEDRFDLHRI EKELGTEIKP 
IPKVIDPALY VANVGASVGD TCNNSDLNNS ANEEGNVSK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.