Nos | FBgn0011676 | NCBI 34495

Details for: Nos

Gene ID: 34495

Symbol: Nos

Ensembl ID: FBgn0011676

Description: Nitric oxide synthase

Associated with

Cardiac conduction
(R-DME-5576891)
Enos activation
(R-DME-203615)
Esr-mediated signaling
(R-DME-8939211)
Extra-nuclear estrogen signaling
(R-DME-9009391)
Hemostasis
(R-DME-109582)
Immune system
(R-DME-168256)
Innate immune system
(R-DME-168249)
Ion homeostasis
(R-DME-5578775)
Metabolism
(R-DME-1430728)
Metabolism of cofactors
(R-DME-8978934)
Metabolism of nitric oxide: nos3 activation and regulation
(R-DME-202131)
Metabolism of vitamins and cofactors
(R-DME-196854)
Muscle contraction
(R-DME-397014)
Nitric oxide stimulates guanylate cyclase
(R-DME-392154)
Nosip mediated enos trafficking
(R-DME-203754)
Peroxisomal protein import
(R-DME-9033241)
Platelet homeostasis
(R-DME-418346)
Protein localization
(R-DME-9609507)
Ros and rns production in phagocytes
(R-DME-1222556)
Signaling by nuclear receptors
(R-DME-9006931)
Signaling by receptor tyrosine kinases
(R-DME-9006934)
Signaling by vegf
(R-DME-194138)
Signal transduction
(R-DME-162582)
Tetrahydrobiopterin (bh4) synthesis, recycling, salvage and regulation
(R-DME-1474151)
Vegfa-vegfr2 pathway
(R-DME-4420097)
Vegfr2 mediated vascular permeability
(R-DME-5218920)
Arginine catabolic process
(GO:0006527)
Calmodulin binding
(GO:0005516)
Cytosol
(GO:0005829)
Flavin adenine dinucleotide binding
(GO:0050660)
Fmn binding
(GO:0010181)
Heme binding
(GO:0020037)
Imaginal disc development
(GO:0007444)
Nadp binding
(GO:0050661)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of dna replication
(GO:0008156)
Nervous system development
(GO:0007399)
Nitric-oxide synthase activity
(GO:0004517)
Nitric oxide biosynthetic process
(GO:0006809)
Nitric oxide mediated signal transduction
(GO:0007263)
Nucleus
(GO:0005634)
Oxidoreductase activity
(GO:0016491)
Peroxisome
(GO:0005777)
Plasma membrane
(GO:0005886)
Positive regulation of guanylate cyclase activity
(GO:0031284)
Regulation of heart rate
(GO:0002027)
Regulation of organ growth
(GO:0046620)
Response to gram-negative bacterium
(GO:0140460)
Response to hormone
(GO:0009725)
Response to lipopolysaccharide
(GO:0032496)
Synapse assembly
(GO:0007416)

Other Information

Proteins

NOS_DROME

Genular Protein ID: 2890615942

Symbol: NOS_DROME

Name: N/A

UniProtKB Accession Codes:

Q27571 A4V0K9 A4V0L0 Q4ABG3 Q4ABG4 Q4ABG5 Q4ABG6 Q4ABG7 Q7YU33 Q9U096 Q9VKP8

Database IDs:

Citations:

PubMed ID: 7568075

Title: Molecular and biochemical characterization of dNOS: a Drosophila Ca2+/calmodulin-dependent nitric oxide synthase.

PubMed ID: 7568075

DOI: 10.1073/pnas.92.20.9072

PubMed ID: 11526108

Title: The Drosophila nitric-oxide synthase gene (dNOS) encodes a family of proteins that can modulate NOS activity by acting as dominant negative regulators.

PubMed ID: 11526108

DOI: 10.1074/jbc.m105066200

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12804606

Title: Characterization of Drosophila nitric oxide synthase: a biochemical study.

PubMed ID: 12804606

DOI: 10.1016/s0006-291x(03)01003-9

Sequence Information:

Length: 1349
Mass: 151715
Checksum: E19D8CBAEFAF76FC
Sequence:

MSQHFTSIFE NLRFVTIKRS TNAQQQQQQQ QQQLQQQQQQ LQQQKAQTQQ QNSRKIKTQA 
TPTLNGNGLL SGNPNGGGGD SSPSHEVDHP GGAQGAQAAG GLPSSSGTPL RHHKRASIST 
ASPPIRERRG TNTSIVVELD GSGSGSGSGG GGVGVGQGAG CPPSGSCTAS GKSSRELSPS 
PKNQQQPRKM SQDYRSRAGS FMHLDDEGRS LLMRKPMRLK NIEGRPEVYD TLHCKGREIL 
SCSKATCTSS IMNIGNAAVE ARKSDLILEH AKDFLEQYFT SIKRTSSTAH ETRWKQVRQS 
IETTGHYQLT ETELIYGAKL AWRNSSRCIG RIQWSKLQVF DCRYVTTTSG MFEAICNHIK 
YATNKGNLRS AITIFPQRTD AKHDYRIWNN QLISYAGYKQ ADGKIIGDPM NVEFTEVCTK 
LGWKSKGSEW DILPLVVSAN GHDPDYFDYP PELILEVPLT HPKFEWFSDL GLRWYALPAV 
SSMLFDVGGI QFTATTFSGW YMSTEIGSRN LCDTNRRNML ETVALKMQLD TRTPTSLWKD 
KAVVEMNIAV LHSYQSRNVT IVDHHTASES FMKHFENESK LRNGCPADWI WIVPPLSGSI 
TPVFHQEMAL YYLKPSFEYQ DPAWRTHVWK KGRGESKGKK PRRKFNFKQI ARAVKFTSKL 
FGRALSKRIK ATVLYATETG KSEQYAKQLC ELLGHAFNAQ IYCMSDYDIS SIEHEALLIV 
VASTFGNGDP PENGELFSQE LYAMRVQESS EHGLQDSSIG SSKSFMKASS RQEFMKLPLQ 
QVKRIDRWDS LRGSTSDTFT EETFGPLSNV RFAVFALGSS AYPNFCAFGQ YVDNILGELG 
GERLLRVAYG DEMCGQEQSF RKWAPEVFKL ACETFCLDPE ESLSDASLAL QNDSLTVNTV 
RLVPSANKGS LDSSLSKYHN KKVHCCKAKA KPHNLTRLSE GAKTTMLLEI CAPGLEYEPG 
DHVGIFPANR TELVDGLLNR LVGVDNPDEV LQLQLLKEKQ TSNGIFKCWE PHDKIPPDTL 
RNLLARFFDL TTPPSRQLLT LLAGFCEDTA DKERLELLVN DSSAYEDWRH WRLPHLLDVL 
EEFPSCRPPA PLLLAQLTPL QPRFYSISSS PRRVSDEIHL TVAIVKYRCE DGQGDERYGV 
CSNYLSGLRA DDELFMFVRS ALGFHLPSDR SRPIILIGPG TGIAPFRSFW QEFQVLSDLD 
PTAKLPKMWL FFGCRNRDVD LYAEEKAELQ KDQILDRVFL ALSREQAIPK TYVQDLIEQE 
FDSLYQLIVQ ERGHIYVCGD VTMAEHVYQT IRKCIAGKEQ KSEAEVETFL LTLRDESRYH 
EDIFGITLRT AEIHTKSRAT ARIRMASQP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nos

Associated with

Other Information

Molecular and biochemical characterization of dNOS: a Drosophila Ca2+/calmodulin-dependent nitric oxide synthase. PubMed ID: 7568075

The Drosophila nitric-oxide synthase gene (dNOS) encodes a family of proteins that can modulate NOS activity by acting as dominant negative regulators. PubMed ID: 11526108

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132