aurB | FBgn0024227 | NCBI 34504

Details for: aurB

Gene ID: 34504

Symbol: aurB

Ensembl ID: FBgn0024227

Description: aurora B

Associated with

Apc/c-mediated degradation of cell cycle proteins
(R-DME-174143)
Apc/c:cdh1 mediated degradation of cdc20 and other apc/c:cdh1 targeted proteins in late mitosis/early g1
(R-DME-174178)
Cell cycle
(R-DME-1640170)
Cell cycle, mitotic
(R-DME-69278)
Gene expression (transcription)
(R-DME-74160)
Generic transcription pathway
(R-DME-212436)
Metabolism of proteins
(R-DME-392499)
Regulation of mitotic cell cycle
(R-DME-453276)
Regulation of tp53 activity
(R-DME-5633007)
Regulation of tp53 activity through phosphorylation
(R-DME-6804756)
Rna polymerase ii transcription
(R-DME-73857)
Sumo e3 ligases sumoylate target proteins
(R-DME-3108232)
Sumoylation
(R-DME-2990846)
Sumoylation of dna replication proteins
(R-DME-4615885)
Transcriptional regulation by tp53
(R-DME-3700989)
Atp binding
(GO:0005524)
Chromatin organization
(GO:0006325)
Chromosome, centromeric region
(GO:0000775)
Chromosome condensation
(GO:0030261)
Chromosome passenger complex
(GO:0032133)
Condensed chromosome, centromeric region
(GO:0000779)
Female germ-line stem cell asymmetric division
(GO:0048132)
Kinetochore
(GO:0000776)
Meiotic spindle midzone
(GO:1990385)
Midbody
(GO:0030496)
Midbody abscission
(GO:0061952)
Mitotic chromosome condensation
(GO:0007076)
Mitotic cytokinesis
(GO:0000281)
Mitotic sister chromatid segregation
(GO:0000070)
Mitotic spindle organization
(GO:0007052)
Post-translational protein modification
(GO:0043687)
Protein kinase activity
(GO:0004672)
Protein serine/threonine/tyrosine kinase activity
(GO:0004712)
Protein serine/threonine kinase activity
(GO:0004674)
Regulation of cytokinesis
(GO:0032465)
Spindle
(GO:0005819)
Spindle microtubule
(GO:0005876)
Spindle midzone
(GO:0051233)
Spindle pole centrosome
(GO:0031616)

Other Information

Proteins

AURKB_DROME

Genular Protein ID: 2163598304

Symbol: AURKB_DROME

Name: N/A

UniProtKB Accession Codes:

Q9VKN7 Q9XTQ0

Database IDs:

Citations:

PubMed ID: 10433558

Title: Cloning, mapping, and expression of ial, a novel Drosophila member of the Ipl1/aurora mitotic control kinase family.

PubMed ID: 10433558

DOI: 10.1089/104454999315141

PubMed ID: 10231582

Title: The Drosophila STAM gene homolog is in a tight gene cluster, and its expression correlates to that of the adjacent gene ial.

PubMed ID: 10231582

DOI: 10.1016/s0378-1119(99)00053-0

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 11266459

Title: Drosophila aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesis.

PubMed ID: 11266459

DOI: 10.1083/jcb.152.4.669

PubMed ID: 11352945

Title: Essential roles of Drosophila inner centromere protein (INCENP) and aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation.

PubMed ID: 11352945

DOI: 10.1083/jcb.153.4.865

PubMed ID: 12374737

Title: Cdc37 is essential for chromosome segregation and cytokinesis in higher eukaryotes.

PubMed ID: 12374737

DOI: 10.1093/emboj/cdf531

PubMed ID: 16824953

Title: INCENP and Aurora B promote meiotic sister chromatid cohesion through localization of the Shugoshin MEI-S332 in Drosophila.

PubMed ID: 16824953

DOI: 10.1016/j.devcel.2006.04.021

Sequence Information:

Length: 329
Mass: 38301
Checksum: B489A0A33A4F2128
Sequence:

MTLSRAKHAN RNHLPHLLAK VPEEHQEPIK NMCLKMMSHD AYGQPYDWSP RDFEMGAHLG 
RGKFGRVYLA RERHSHYLVA MKVMFKEELR KGCVQRQVLR EIEIQSRLKH PHILRLLTWF 
HDESRIYLAL EIASEGELFK HLRGAPNHRF DEPRSAKYTY QVANALNYCH LNNVIHRDLK 
PENILLTSTD DLKLADFGWS AHTPNNKRRT LCGTLDYLPP EMVDGNSYDD SVDQWCLGIL 
CYEFVVGCPP FESNSTESTY SKIRRMEISY PSHLSKGCKE LIGGLLRKES KGRITLVDVM 
THYWVKAGMA ERELQLQKRE RGKENTARN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: aurB

Associated with

Other Information

Cloning, mapping, and expression of ial, a novel Drosophila member of the Ipl1/aurora mitotic control kinase family. PubMed ID: 10433558

The Drosophila STAM gene homolog is in a tight gene cluster, and its expression correlates to that of the adjacent gene ial. PubMed ID: 10231582

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila full-length cDNA resource. PubMed ID: 12537569

Drosophila aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesis. PubMed ID: 11266459

Essential roles of Drosophila inner centromere protein (INCENP) and aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation. PubMed ID: 11352945

Cdc37 is essential for chromosome segregation and cytokinesis in higher eukaryotes. PubMed ID: 12374737

INCENP and Aurora B promote meiotic sister chromatid cohesion through localization of the Shugoshin MEI-S332 in Drosophila. PubMed ID: 16824953