Details for: aub

Gene ID: 34524

Symbol: aub

Ensembl ID: FBgn0000146

Description: aubergine

Associated with

Other Information

Genular Protein ID: 2135502170

Symbol: AUB_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8676882

Title: A newly identified Minute locus, M(2)32D, encodes the ribosomal protein L9 in Drosophila melanogaster.

PubMed ID: 8676882

DOI: 10.1007/bf02172530

PubMed ID: 9927466

Title: Genetic and molecular characterization of sting, a gene involved in crystal formation and meiotic drive in the male germ line of Drosophila melanogaster.

PubMed ID: 9927466

DOI: 10.1093/genetics/151.2.749

PubMed ID: 22997235

Title: Long-term and short-term evolutionary impacts of transposable elements on Drosophila.

PubMed ID: 22997235

DOI: 10.1534/genetics.112.145714

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 1783295

Title: Female sterile mutations on the second chromosome of Drosophila melanogaster. II. Mutations blocking oogenesis or altering egg morphology.

PubMed ID: 1783295

DOI: 10.1093/genetics/129.4.1119

PubMed ID: 8625849

Title: aubergine enhances oskar translation in the Drosophila ovary.

PubMed ID: 8625849

DOI: 10.1242/dev.122.5.1631

PubMed ID: 11526087

Title: Aubergine encodes a Drosophila polar granule component required for pole cell formation and related to eIF2C.

PubMed ID: 11526087

DOI: 10.1242/dev.128.14.2823

PubMed ID: 12154120

Title: RNAi is activated during Drosophila oocyte maturation in a manner dependent on aubergine and spindle-E.

PubMed ID: 12154120

DOI: 10.1101/gad.990802

PubMed ID: 12538514

Title: Maelstrom, a Drosophila spindle-class gene, encodes a protein that colocalizes with Vasa and RDE1/AGO1 homolog, Aubergine, in nuage.

PubMed ID: 12538514

DOI: 10.1242/dev.00310

PubMed ID: 15035984

Title: The Drosophila SDE3 homolog armitage is required for oskar mRNA silencing and embryonic axis specification.

PubMed ID: 15035984

DOI: 10.1016/s0092-8674(04)00250-8

PubMed ID: 15090597

Title: Live imaging of nuage and polar granules: evidence against a precursor-product relationship and a novel role for Oskar in stabilization of polar granule components.

PubMed ID: 15090597

DOI: 10.1242/jcs.01059

PubMed ID: 15372228

Title: aubergine mutations in Drosophila melanogaster impair P cytotype determination by telomeric P elements inserted in heterochromatin.

PubMed ID: 15372228

DOI: 10.1007/s00438-004-1061-1

PubMed ID: 14752161

Title: Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery.

PubMed ID: 14752161

DOI: 10.1126/science.1092653

PubMed ID: 16452506

Title: Telomere elongation is under the control of the RNAi-based mechanism in the Drosophila germline.

PubMed ID: 16452506

DOI: 10.1101/gad.370206

PubMed ID: 17346786

Title: Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila.

PubMed ID: 17346786

DOI: 10.1016/j.cell.2007.01.043

PubMed ID: 17428915

Title: Unique germ-line organelle, nuage, functions to repress selfish genetic elements in Drosophila melanogaster.

PubMed ID: 17428915

DOI: 10.1073/pnas.0701920104

PubMed ID: 17872506

Title: Gene silencing mechanisms mediated by Aubergine piRNA complexes in Drosophila male gonad.

PubMed ID: 17872506

DOI: 10.1261/rna.744307

PubMed ID: 17322028

Title: A slicer-mediated mechanism for repeat-associated siRNA 5' end formation in Drosophila.

PubMed ID: 17322028

DOI: 10.1126/science.1140494

PubMed ID: 18590813

Title: Isolation of new polar granule components in Drosophila reveals P body and ER associated proteins.

PubMed ID: 18590813

DOI: 10.1016/j.mod.2008.06.005

PubMed ID: 19395009

Title: Collapse of germline piRNAs in the absence of Argonaute3 reveals somatic piRNAs in flies.

PubMed ID: 19395009

DOI: 10.1016/j.cell.2009.04.027

PubMed ID: 19959991

Title: Functional involvement of Tudor and dPRMT5 in the piRNA processing pathway in Drosophila germlines.

PubMed ID: 19959991

DOI: 10.1038/emboj.2009.365

PubMed ID: 19377467

Title: Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stability.

PubMed ID: 19377467

DOI: 10.1038/ncb1872

PubMed ID: 20953170

Title: Maternal mRNA deadenylation and decay by the piRNA pathway in the early Drosophila embryo.

PubMed ID: 20953170

DOI: 10.1038/nature09465

PubMed ID: 19926723

Title: Arginine methylation of Aubergine mediates Tudor binding and germ plasm localization.

PubMed ID: 19926723

DOI: 10.1261/rna.1869710

PubMed ID: 20980675

Title: Biogenesis pathways of piRNAs loaded onto AGO3 in the Drosophila testis.

PubMed ID: 20980675

DOI: 10.1261/rna.2270710

PubMed ID: 21447556

Title: PAPI, a novel TUDOR-domain protein, complexes with AGO3, ME31B and TRAL in the nuage to silence transposition.

PubMed ID: 21447556

DOI: 10.1242/dev.059287

PubMed ID: 21831924

Title: Vreteno, a gonad-specific protein, is essential for germline development and primary piRNA biogenesis in Drosophila.

PubMed ID: 21831924

DOI: 10.1242/dev.069187

PubMed ID: 20937269

Title: Aubergine is a component of a nanos mRNA localization complex.

PubMed ID: 20937269

DOI: 10.1016/j.ydbio.2010.10.002

PubMed ID: 22303351

Title: Gender-Specific Hierarchy in Nuage Localization of PIWI-Interacting RNA Factors in Drosophila.

PubMed ID: 22303351

DOI: 10.3389/fgene.2011.00055

PubMed ID: 23267055

Title: Mutations to the piRNA pathway component Aubergine enhance meiotic drive of segregation distorter in Drosophila melanogaster.

PubMed ID: 23267055

DOI: 10.1534/genetics.112.147561

PubMed ID: 23559253

Title: Transposition-driven genomic heterogeneity in the Drosophila brain.

PubMed ID: 23559253

DOI: 10.1126/science.1231965

PubMed ID: 26212455

Title: Krimper Enforces an Antisense Bias on piRNA Pools by Binding AGO3 in the Drosophila Germline.

PubMed ID: 26212455

DOI: 10.1016/j.molcel.2015.06.024

PubMed ID: 26295961

Title: Aub and Ago3 Are Recruited to Nuage through Two Mechanisms to Form a Ping-Pong Complex Assembled by Krimper.

PubMed ID: 26295961

DOI: 10.1016/j.molcel.2015.07.017

PubMed ID: 28945271

Title: An in vivo proteomic analysis of the Me31B interactome in Drosophila germ granules.

PubMed ID: 28945271

DOI: 10.1002/1873-3468.12854

PubMed ID: 20713507

Title: Structural basis for methylarginine-dependent recognition of Aubergine by Tudor.

PubMed ID: 20713507

DOI: 10.1101/gad.1956010

PubMed ID: 34210982

Title: Binding of guide piRNA triggers methylation of the unstructured N-terminal region of Aub leading to assembly of the piRNA amplification complex.

PubMed ID: 34210982

DOI: 10.1038/s41467-021-24351-x

Sequence Information:

  • Length: 866
  • Mass: 98559
  • Checksum: 8F84CF1B0B89103B
  • Sequence:
  • MNLPPNPVIA RGRGRGRKPN NVEANRGFAP SLGQKSDPSH SEGNQASGGN GGGGDAQVGP 
    SIEKSSLSAV QMHKSEGDPR GSVRGRRLIT DLVYSRPPGM TSKKGVVGTH ITVQANYFKV 
    LKRPNWTIYQ YRVDFTPDVE ATRLRRSFLY EHKGILGGYI FDGTNMFCIN QFKAVQDSPY 
    VLELVTKSRA GENIEIKIKA VGSVQSTDAE QFQVLNLILR RAMEGLDLKL VSRYYYDPQA 
    KINLENFRMQ LWPGYQTSIR QHENDILLCS EICHKVMRTE TLYNILSDAI RDSDDYQSTF 
    KRAVMGMVIL TDYNNKTYRI DDVDFQSTPL CKFKTNDGEI SYVDYYKKRY NIIIRDLKQP 
    LVMSRPTDKN IRGGNDQAIM IIPELARATG MTDAMRADFR TLRAMSEHTR LNPDRRIERL 
    RMFNKRLKSC KQSVETLKSW NIELDSALVE IPARVLPPEK ILFGNQKIFV CDARADWTNE 
    FRTCSMFKNV HINRWYVITP SRNLRETQEF VQMCIRTASS MKMNICNPIY EEIPDDRNGT 
    YSQAIDNAAA NDPQIVMVVM RSPNEEKYSC IKKRTCVDRP VPSQVVTLKV IAPRQQKPTG 
    LMSIATKVVI QMNAKLMGAP WQVVIPLHGL MTVGFDVCHS PKNKNKSYGA FVATMDQKES 
    FRYFSTVNEH IKGQELSEQM SVNMACALRS YQEQHRSLPE RILFFRDGVG DGQLYQVVNS 
    EVNTLKDRLD EIYKSAGKQE GCRMTFIIVS KRINSRYFTG HRNPVPGTVV DDVITLPERY 
    DFFLVSQAVR IGTVSPTSYN VISDNMGLNA DKLQMLSYKM THMYYNYSGT IRVPAVCHYA 
    HKLAFLVAES INRAPSAGLQ NQLYFL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.