Details for: esc

Gene ID: 34595

Symbol: esc

Ensembl ID: FBgn0000588

Description: extra sexcombs

Associated with

Other Information

Genular Protein ID: 2073956225

Symbol: ESC_DROME

Name: Polycomb protein esc

UniProtKB Accession Codes:

Q24338

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CTD 1 ComplexPortal 2 DIP 1 DNASU 1 EMBL 3 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 1 GO 13 Gene3D 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MINT 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 3 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 7556071

Title: The Polycomb-group gene, extra sex combs, encodes a nuclear member of the WD-40 repeat family.

PubMed ID: 7556071

DOI: 10.1002/j.1460-2075.1995.tb00104.x

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 9566901

Title: The Drosophila esc and E(z) proteins are direct partners in polycomb group-mediated repression.

PubMed ID: 9566901

DOI: 10.1128/mcb.18.5.2825

PubMed ID: 10757791

Title: A Drosophila ESC-E(Z) protein complex is distinct from other polycomb group complexes and contains covalently modified ESC.

PubMed ID: 10757791

DOI: 10.1128/mcb.20.9.3069-3078.2000

PubMed ID: 11124122

Title: The Drosophila polycomb group proteins ESC and E(Z) are present in a complex containing the histone-binding protein p55 and the histone deacetylase RPD3.

PubMed ID: 11124122

DOI: 10.1242/dev.128.2.275

PubMed ID: 11581156

Title: Establishment of Polycomb silencing requires a transient interaction between PC and ESC.

PubMed ID: 11581156

DOI: 10.1101/gad.208901

PubMed ID: 12408863

Title: Drosophila Enhancer of zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites.

PubMed ID: 12408863

DOI: 10.1016/s0092-8674(02)00975-3

PubMed ID: 12408864

Title: Histone methyltransferase activity of a Drosophila Polycomb group repressor complex.

PubMed ID: 12408864

DOI: 10.1016/s0092-8674(02)00976-5

PubMed ID: 12533794

Title: Polycomb group proteins ESC and E(Z) are present in multiple distinct complexes that undergo dynamic changes during development.

PubMed ID: 12533794

DOI: 10.1002/gene.10173

PubMed ID: 12697833

Title: A 1-megadalton ESC/E(Z) complex from Drosophila that contains polycomblike and RPD3.

PubMed ID: 12697833

DOI: 10.1128/mcb.23.9.3352-3362.2003

PubMed ID: 12771214

Title: The Drosophila Corto protein interacts with Polycomb-group proteins and the GAGA factor.

PubMed ID: 12771214

DOI: 10.1093/nar/gkg381

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

Sequence Information:

  • Length: 425
  • Mass: 47988
  • Checksum: 511C305E5DE86727
  • Sequence:
    • MSSDKVKNGN EPEESEESCG DESASYTTNS TTSRSKSPSS STRSKRRGRR STKSKPKSRA 
AYKYDTHVKE NHGANIFGVA FNTLLGKDEP QVFATAGSNR VTVYECPRQG GMQLLHCYAD 
PDPDEVFYTC AWSYDLKTSS PLLAAAGYRG VIRVIDVEQN EAVGNYIGHG QAINELKFHP 
HKLQLLLSGS KDHAIRLWNI QSHVCIAILG GVEGHRDEVL SIDFNMRGDR IVSSGMDHSL 
KLWCLNTPEF HHKIELSNTF SQEKSTLPFP TVTKHFPDFS TRDIHRNYVD CVQWFGNFVL 
SKSCENAIVC WKPGQLHQSF EQVKPSDSSC TIIAEFEYDE CEIWFVRFGF NPWQKVIALG 
NQQGKVYVWE LDPSDPEGAH MTTLHNSRSV ATVRQIAFSR DASVLVYVCD DATVWRWNRR 
QTTSI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.