Details for: grp

Gene ID: 34993

Symbol: grp

Ensembl ID: FBgn0261278

Description: grapes

Associated with

Other Information

Genular Protein ID: 3165136

Symbol: CHK1_DROME

Name: Serine/threonine-protein kinase grp

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9197245

Title: The Drosophila grapes gene is related to checkpoint gene chk1/rad27 and is required for late syncytial division fidelity.

PubMed ID: 9197245

DOI: 10.1016/s0960-9822(06)00189-8

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 7925016

Title: The Drosophila maternal-effect mutation grapes causes a metaphase arrest at nuclear cycle 13.

PubMed ID: 7925016

DOI: 10.1242/dev.120.8.2131

PubMed ID: 9214509

Title: DNA-replication checkpoint control at the Drosophila midblastula transition.

PubMed ID: 9214509

DOI: 10.1038/40439

PubMed ID: 10209095

Title: The Drosophila ATM homologue Mei-41 has an essential checkpoint function at the midblastula transition.

PubMed ID: 10209095

DOI: 10.1016/s0960-9822(99)80138-9

PubMed ID: 10469601

Title: Drosophila grapes/CHK1 mutants are defective in cyclin proteolysis and coordination of mitotic events.

PubMed ID: 10469601

DOI: 10.1016/s0960-9822(99)80399-6

PubMed ID: 10980701

Title: The grapes checkpoint coordinates nuclear envelope breakdown and chromosome condensation.

PubMed ID: 10980701

DOI: 10.1038/35023555

PubMed ID: 12172011

Title: Chk2 regulates irradiation-induced, p53-mediated apoptosis in Drosophila.

PubMed ID: 12172011

DOI: 10.1073/pnas.172382899

PubMed ID: 12919679

Title: Control of cleavage cycles in Drosophila embryos by fruhstart.

PubMed ID: 12919679

DOI: 10.1016/s1534-5807(03)00208-9

PubMed ID: 14711410

Title: Relative contribution of DNA repair, cell cycle checkpoints, and cell death to survival after DNA damage in Drosophila larvae.

PubMed ID: 14711410

DOI: 10.1016/j.cub.2003.12.032

PubMed ID: 15723794

Title: The Drosophila Grp/Chk1 DNA damage checkpoint controls entry into anaphase.

PubMed ID: 15723794

DOI: 10.1016/j.cub.2005.02.026

PubMed ID: 15860729

Title: Grp/DChk1 is required for G2-M checkpoint activation in Drosophila S2 cells, whereas Dmnk/DChk2 is dispensable.

PubMed ID: 15860729

DOI: 10.1242/jcs.02309

PubMed ID: 16079276

Title: Regulation of mitosis in response to damaged or incompletely replicated DNA require different levels of grapes (Drosophila Chk1).

PubMed ID: 16079276

DOI: 10.1242/jcs.02454

PubMed ID: 22796626

Title: Drosophila Claspin is required for the G2 arrest that is induced by DNA replication stress but not by DNA double-strand breaks.

PubMed ID: 22796626

DOI: 10.1016/j.dnarep.2012.06.007

PubMed ID: 34644293

Title: dRTEL1 is essential for the maintenance of Drosophila male germline stem cells.

PubMed ID: 34644293

DOI: 10.1371/journal.pgen.1009834

Sequence Information:

  • Length: 512
  • Mass: 57833
  • Checksum: 504CAB3C0B642EA0
  • Sequence:
  • MAATLTEAGT GPAATREFVE GWTLAQTLGE GAYGEVKLLI NRQTGEAVAM KMVDLKKHPD 
    AANSVRKEVC IQKMLQDKHI LRFFGKRSQG SVEYIFLEYA AGGELFDRIE PDVGMPQHEA 
    QRYFTQLLSG LNYLHQRGIA HRDLKPENLL LDEHDNVKIS DFGMATMFRC KGKERLLDKR 
    CGTLPYVAPE VLQKAYHAQP ADLWSCGVIL VTMLAGELPW DQPSTNCTEF TNWRDNDHWQ 
    LQTPWSKLDT LAISLLRKLL ATSPGTRLTL EKTLDHKWCN MQFADNERSY DLVDSAAALE 
    ICSPKAKRQR LQSSAHLSNG LDDSISRNYC SQPMPTMRSD DDFNVRLGSG RSKEDGGDRQ 
    TLAQEARLSY SFSQPALLDD LLLATQMNQT QNASQNYFQR LVRRMTRFFV TTRWDDTIKR 
    LVGTIERLGG YTCKFGDDGV VTVSTVDRNK LRLVFKAHII EMDGKILVDC RLSKGCGLEF 
    KRRFIKIKNA LEDIVLKGPT TWPIAIATNS VP

Genular Protein ID: 1398757246

Symbol: Q59DY7_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

PubMed ID: 26109357

Title: Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.

PubMed ID: 26109357

DOI: .1534/g3.115.018929

PubMed ID: 26109356

Title: Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.

PubMed ID: 26109356

DOI: .1534/g3.115.018937

PubMed ID: 25589440

Title: The Release 6 reference sequence of the Drosophila melanogaster genome.

PubMed ID: 25589440

Sequence Information:

  • Length: 398
  • Mass: 45333
  • Checksum: 0331103CB69ADA57
  • Sequence:
  • MPQHEAQRYF TQLLSGLNYL HQRGIAHRDL KPENLLLDEH DNVKISDFGM ATMFRCKGKE 
    RLLDKRCGTL PYVAPEVLQK AYHAQPADLW SCGVILVTML AGELPWDQPS TNCTEFTNWR 
    DNDHWQLQTP WSKLDTLAIS LLRKLLATSP GTRLTLEKTL DHKWCNMQFA DNERSYDLVD 
    SAAALEICSP KAKRQRLQSS AHLSNGLDDS ISRNYCSQPM PTMRSDDDFN VRLGSGRSKE 
    DGGDRQTLAQ EARLSYSFSQ PALLDDLLLA TQMNQTQNAS QNYFQRLVRR MTRFFVTTRW 
    DDTIKRLVGT IERLGGYTCK FGDDGVVTVS TVDRNKLRLV FKAHIIEMDG KILVDCRLSK 
    GCGLEFKRRF IKIKNALEDI VLKGPTTWPI AIATNSVP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.