Details for: ACADS

Gene ID: 35

Symbol: ACADS

Ensembl ID: ENSG00000122971

Description: acyl-CoA dehydrogenase short chain

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 45.6152
    Cell Significance Index: -11.5700
  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 44.6815
    Cell Significance Index: -6.9500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 35.9994
    Cell Significance Index: -14.6300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 34.7367
    Cell Significance Index: -16.4000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 33.1852
    Cell Significance Index: -17.0700
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 24.6639
    Cell Significance Index: -16.5500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 11.1683
    Cell Significance Index: -13.7700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 4.9984
    Cell Significance Index: -13.3900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 3.9077
    Cell Significance Index: -15.4200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 3.3567
    Cell Significance Index: -10.3100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 2.7604
    Cell Significance Index: 165.7200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.6415
    Cell Significance Index: 119.7300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 2.0408
    Cell Significance Index: 1842.7100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.8538
    Cell Significance Index: 216.0400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.8237
    Cell Significance Index: 39.5100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.6635
    Cell Significance Index: 47.9300
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.3715
    Cell Significance Index: 20.5500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.2299
    Cell Significance Index: 32.9600
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.7224
    Cell Significance Index: 12.1500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.6981
    Cell Significance Index: 132.8600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6673
    Cell Significance Index: 66.0100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.6457
    Cell Significance Index: 20.6800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.6209
    Cell Significance Index: 42.9400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.5591
    Cell Significance Index: 41.6700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4659
    Cell Significance Index: 24.2000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4600
    Cell Significance Index: 318.1300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4529
    Cell Significance Index: 89.8800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.4356
    Cell Significance Index: 20.3100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.3359
    Cell Significance Index: 8.5800
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.3291
    Cell Significance Index: 8.0300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.3235
    Cell Significance Index: 6.8900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3175
    Cell Significance Index: 57.2400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2908
    Cell Significance Index: 47.3000
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.2359
    Cell Significance Index: 3.3800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2232
    Cell Significance Index: 27.4500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.2215
    Cell Significance Index: 2.0400
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 0.2191
    Cell Significance Index: 1.8400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1992
    Cell Significance Index: 27.3500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1959
    Cell Significance Index: 106.9800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1770
    Cell Significance Index: 6.2200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1731
    Cell Significance Index: 13.2800
  • Cell Name: columnar/cuboidal epithelial cell (CL0000075)
    Fold Change: 0.1645
    Cell Significance Index: 0.6300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1629
    Cell Significance Index: 20.8800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1409
    Cell Significance Index: 62.2900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1170
    Cell Significance Index: 3.2700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0925
    Cell Significance Index: 2.4700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0902
    Cell Significance Index: 15.4100
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 0.0873
    Cell Significance Index: 0.3800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0861
    Cell Significance Index: 6.0900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0749
    Cell Significance Index: 9.6800
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 0.0664
    Cell Significance Index: 0.6700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0663
    Cell Significance Index: 3.4600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.0637
    Cell Significance Index: 0.9400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0619
    Cell Significance Index: 12.4100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0616
    Cell Significance Index: 7.0600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0501
    Cell Significance Index: 3.2300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.0306
    Cell Significance Index: 0.9000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0291
    Cell Significance Index: 10.4400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0238
    Cell Significance Index: 0.6300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0035
    Cell Significance Index: 2.6800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0002
    Cell Significance Index: -0.3000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0048
    Cell Significance Index: -8.9300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0049
    Cell Significance Index: -0.2300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0056
    Cell Significance Index: -4.1400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0080
    Cell Significance Index: -12.3100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0102
    Cell Significance Index: -1.0400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0107
    Cell Significance Index: -14.5400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0176
    Cell Significance Index: -11.1700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0190
    Cell Significance Index: -14.1000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0198
    Cell Significance Index: -8.9900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0236
    Cell Significance Index: -13.3100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0281
    Cell Significance Index: -17.5400
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0319
    Cell Significance Index: -0.2600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0417
    Cell Significance Index: -12.0000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0575
    Cell Significance Index: -8.3600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0584
    Cell Significance Index: -1.4600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0691
    Cell Significance Index: -8.1500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0785
    Cell Significance Index: -2.1000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0820
    Cell Significance Index: -17.2800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0920
    Cell Significance Index: -1.5400
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1009
    Cell Significance Index: -1.0500
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: -0.1121
    Cell Significance Index: -0.6900
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.1264
    Cell Significance Index: -2.1300
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1316
    Cell Significance Index: -3.0400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1430
    Cell Significance Index: -14.8900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.1521
    Cell Significance Index: -4.1400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1524
    Cell Significance Index: -8.0000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1583
    Cell Significance Index: -12.5400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1868
    Cell Significance Index: -10.4800
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1868
    Cell Significance Index: -3.9100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1920
    Cell Significance Index: -11.7700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1962
    Cell Significance Index: -9.9200
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.2022
    Cell Significance Index: -2.9900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2183
    Cell Significance Index: -13.4200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2191
    Cell Significance Index: -14.7300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2229
    Cell Significance Index: -5.7300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.2360
    Cell Significance Index: -3.2200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2443
    Cell Significance Index: -15.4000
  • Cell Name: enterocyte (CL0000584)
    Fold Change: -0.2643
    Cell Significance Index: -1.6400
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.2749
    Cell Significance Index: -5.8800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Location and Expression:** ACADS is located in the mitochondria, where it plays a pivotal role in fatty acid metabolism. Its expression is widespread, with significant levels found in enterocytes, colon epithelial cells, and stem cells. 2. **Function:** ACADS is an acyl-CoA dehydrogenase enzyme that catalyzes the initial step of beta-oxidation of short-chain fatty acids, converting them into acetyl-CoA. This reaction is crucial for energy production and lipid metabolism. 3. **Substrate Specificity:** ACADS has a high specificity for short-chain fatty acids, with a preference for butyrate and hexanoyl-CoA. 4. **Regulation:** ACADS is regulated by various mechanisms, including allosteric control, transcriptional regulation, and post-translational modifications. **Pathways and Functions:** 1. **Beta-Oxidation of Fatty Acids:** ACADS is involved in the beta-oxidation of short-chain fatty acids, which is a crucial step in energy production and lipid metabolism. 2. **Fatty Acid Metabolism:** ACADS plays a key role in the metabolism of fatty acids, including the conversion of butyrate and hexanoyl-CoA into acetyl-CoA. 3. **Mitochondrial Function:** ACADS is essential for mitochondrial function, as it contributes to the production of ATP and other energy-rich molecules. 4. **Lipid Metabolism:** ACADS is involved in the lipid metabolism, including the breakdown of fatty acids and the production of energy-rich molecules. **Clinical Significance:** 1. **Metabolic Disorders:** Deficiencies in ACADS have been associated with severe metabolic disorders, including acute fatty liver of infancy, cardiomyopathy, and peripheral neuropathy. 2. **Fatty Acid Metabolism Disorders:** ACADS mutations can lead to impaired fatty acid metabolism, resulting in energy deficits and metabolic imbalances. 3. **Cancer and Inflammation:** ACADS has been implicated in cancer and inflammation, as it plays a role in the regulation of fatty acid metabolism and energy production. 4. **Nutritional and Environmental Factors:** ACADS expression and function can be influenced by nutritional and environmental factors, such as diet and exposure to pollutants. In conclusion, ACADS is a critical gene involved in fatty acid metabolism, energy production, and lipid metabolism. Its dysregulation can lead to severe metabolic disorders, highlighting the importance of this gene in human health. Further research is needed to elucidate the mechanisms underlying ACADS function and to develop therapeutic strategies for the treatment of metabolic disorders associated with ACADS mutations.

Genular Protein ID: 1689682434

Symbol: ACADS_HUMAN

Name: Short-chain specific acyl-CoA dehydrogenase, mitochondrial

UniProtKB Accession Codes:

P16219 P78331

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 27 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 EC 2 EMBL 6 EMDB 1 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 11 Gene3D 3 GeneCards 1 GeneReviews 1 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 1 PIRSF 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 2 Rhea 16 SABIO-RK 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissLipids 1 SwissPalm 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2565344

Title: Molecular cloning and nucleotide sequence of complementary DNAs encoding human short chain acyl-coenzyme A dehydrogenase and the study of the molecular basis of human short chain acyl-coenzyme A dehydrogenase deficiency.

PubMed ID: 2565344

DOI: 10.1172/jci114058

PubMed ID: 9383286

Title: Structural organization of the human short-chain acyl-CoA dehydrogenase gene.

PubMed ID: 9383286

DOI: 10.1007/s003359900612

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1286669

Title: Human liver protein map: a reference database established by microsequencing and gel comparison.

PubMed ID: 1286669

DOI: 10.1002/elps.11501301201

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21237683

Title: Identification and characterization of new long chain acyl-CoA dehydrogenases.

PubMed ID: 21237683

DOI: 10.1016/j.ymgme.2010.12.005

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 1692038

Title: Identification of two variant short chain acyl-coenzyme A dehydrogenase alleles, each containing a different point mutation in a patient with short chain acyl-coenzyme A dehydrogenase deficiency.

PubMed ID: 1692038

DOI: 10.1172/jci114607

PubMed ID: 9499414

Title: Identification of four new mutations in the short-chain acyl-CoA dehydrogenase (SCAD) gene in two patients: one of the variant alleles, 511C-->T, is present at an unexpectedly high frequency in the general population, as was the case for 625G-->A, together conferring susceptibility to ethylmalonic aciduria.

PubMed ID: 9499414

DOI: 10.1093/hmg/7.4.619

PubMed ID: 11134486

Title: Role of common gene variations in the molecular pathogenesis of short-chain acyl-CoA dehydrogenase deficiency.

PubMed ID: 11134486

DOI: 10.1203/00006450-200101000-00008

Sequence Information:

  • Length: 412
  • Mass: 44297
  • Checksum: 3E946ADFC3DA3C0E
  • Sequence:
    • MAAALLARAS GPARRALCPR AWRQLHTIYQ SVELPETHQM LLQTCRDFAE KELFPIAAQV 
DKEHLFPAAQ VKKMGGLGLL AMDVPEELGG AGLDYLAYAI AMEEISRGCA STGVIMSVNN 
SLYLGPILKF GSKEQKQAWV TPFTSGDKIG CFALSEPGNG SDAGAASTTA RAEGDSWVLN 
GTKAWITNAW EASAAVVFAS TDRALQNKGI SAFLVPMPTP GLTLGKKEDK LGIRGSSTAN 
LIFEDCRIPK DSILGEPGMG FKIAMQTLDM GRIGIASQAL GIAQTALDCA VNYAENRMAF 
GAPLTKLQVI QFKLADMALA LESARLLTWR AAMLKDNKKP FIKEAAMAKL AASEAATAIS 
HQAIQILGGM GYVTEMPAER HYRDARITEI YEGTSEIQRL VIAGHLLRSY RS

Genular Protein ID: 140606007

Symbol: B4DUH1_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DUH1

Database IDs:

ARBA 11 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 16 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 5 Gene3D 3 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PROSITE 1 Pfam 4 RefSeq 1 Rhea 12 SMR 1 SUPFAM 2

Sequence Information:

  • Length: 405
  • Mass: 43631
  • Checksum: F82DC5F0E93C6C53
  • Sequence:
    • MAAALLARAS GPARRALCPR AWRQLHTIYQ SVELPETHQM LLQTCRDFAE KELFPIAAQV 
DKEHLFPAAQ VKKMGGLGLL AMDVPEELGG AGLDYLAYAI AMEEISRGCA STGVIMSVNN 
SLYLGPILKF GSKEQKQAWV TPFTSGDKIG CFALSEPGPS LLGPTGPIFA LGQVGCPCPS 
SAATEACTFP RSRQRVSRPE LPREGISAFL VPMPTPGLTL GKKEDKLGIR GSSTANLIFE 
DCRIPKDSIL GEPGMGFKIA MQTLDMGRIG IASQALGIAQ TALDCAVSYA ENRMAFGAPL 
TKLQVIQFKL ADMALALESA RLLTWRAAML KDNKKPFIKE AAMAASEAAT AISHQAIQIL 
GGMGYVTEMP AERHYRDARI TEIYEGTSEI QRLVIAGHLL RSHRS

Genular Protein ID: 3995396785

Symbol: E9PE82_HUMAN

Name: N/A

UniProtKB Accession Codes:

E9PE82

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 16 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 3 GeneTree 1 HGNC 1 InterPro 7 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PROSITE 1 PeptideAtlas 2 Pfam 4 Proteomes 2 ProteomicsDB 2 RefSeq 1 Rhea 12 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 408
  • Mass: 44012
  • Checksum: 9C0DA2EA8B24E6A1
  • Sequence:
    • MAAALLARAS GPARRALCPR AWRQLHTIYQ SVELPETHQM LLQTCRDFAE KELFPIAAQV 
DKEHLFPAAQ VKKMGGLGLL AMDVPEELGG AGLDYLAYAI AMEEISRGCA STGVIMSVNN 
SLYLGPILKF GSKEQKQAWV TPFTSGDKIG CFALSEPGPS LLGPTGPIFA LGQVGCPCPS 
SAATEACTFP RSRQRVSRPE LLREGISAFL VPMPTPGLTL GKKEDKLGIR GSSTANLIFE 
DCRIPKDSIL GEPGMGFKIA MQTLDMGRIG IASQALGIAQ TALDCAVNYA ENRMAFGAPL 
TKLQVIQFKL ADMALALESA RLLTWRAAML KDNKKPFIKE AAMAKLAASE AATAISHQAI 
QILGGMGYVT EMPAERHYRD ARITEIYEGT SEIQRLVIAG HLLRSYRS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.