Details for: APOH
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: liver dendritic cell (CL2000055)
Fold Change: 47.6923
Cell Significance Index: 125.8100 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 4.3054
Cell Significance Index: 72.5300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 4.1853
Cell Significance Index: 830.5800 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 3.4407
Cell Significance Index: -3.2900 - Cell Name: intrahepatic cholangiocyte (CL0002538)
Fold Change: 2.2728
Cell Significance Index: 8.5600 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 2.1809
Cell Significance Index: 32.1900 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 2.1003
Cell Significance Index: 12.1000 - Cell Name: hepatic pit cell (CL2000054)
Fold Change: 1.8198
Cell Significance Index: 4.8800 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 1.2700
Cell Significance Index: 12.5300 - Cell Name: inflammatory macrophage (CL0000863)
Fold Change: 1.2003
Cell Significance Index: 9.2200 - Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
Fold Change: 0.9586
Cell Significance Index: 3.3400 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 0.6915
Cell Significance Index: 16.7500 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 0.6701
Cell Significance Index: 5.2900 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.5841
Cell Significance Index: 111.1500 - Cell Name: proerythroblast (CL0000547)
Fold Change: 0.4019
Cell Significance Index: 5.7600 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.3876
Cell Significance Index: 23.2700 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 0.3422
Cell Significance Index: 10.0800 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.2724
Cell Significance Index: 29.6300 - Cell Name: PP cell (CL0000696)
Fold Change: 0.2695
Cell Significance Index: 2.7400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.2417
Cell Significance Index: 23.9100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2156
Cell Significance Index: 194.6300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.1896
Cell Significance Index: 3.2500 - Cell Name: hepatoblast (CL0005026)
Fold Change: 0.1879
Cell Significance Index: 3.1600 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.1574
Cell Significance Index: 25.6100 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.1467
Cell Significance Index: 3.9300 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.1425
Cell Significance Index: 1.3600 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.1418
Cell Significance Index: 1.9500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.1401
Cell Significance Index: 9.6900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.1094
Cell Significance Index: 2.3700 - Cell Name: Kupffer cell (CL0000091)
Fold Change: 0.1082
Cell Significance Index: 0.9900 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: 0.0819
Cell Significance Index: 1.1500 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 0.0698
Cell Significance Index: 0.7200 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.0667
Cell Significance Index: 0.6900 - Cell Name: pancreatic epsilon cell (CL0005019)
Fold Change: 0.0550
Cell Significance Index: 0.5100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0517
Cell Significance Index: 1.4900 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 0.0497
Cell Significance Index: 0.6400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.0419
Cell Significance Index: 4.8000 - Cell Name: acinar cell (CL0000622)
Fold Change: 0.0287
Cell Significance Index: 0.3600 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0278
Cell Significance Index: 1.2600 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: 0.0182
Cell Significance Index: 2.0800 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.0147
Cell Significance Index: 0.1900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0115
Cell Significance Index: 1.9700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.0109
Cell Significance Index: 3.1300 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0103
Cell Significance Index: 7.8300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0093
Cell Significance Index: 1.8700 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 0.0083
Cell Significance Index: 0.1300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0065
Cell Significance Index: 0.2300 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.0050
Cell Significance Index: 0.0700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.0033
Cell Significance Index: 2.4500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0009
Cell Significance Index: 1.7500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0007
Cell Significance Index: 0.2400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0007
Cell Significance Index: 1.0100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0006
Cell Significance Index: 1.0700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0004
Cell Significance Index: 0.0100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0000
Cell Significance Index: 0.0000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0001
Cell Significance Index: -0.0500 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0005
Cell Significance Index: -0.0100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0006
Cell Significance Index: -0.1300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0007
Cell Significance Index: -0.4000 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: -0.0013
Cell Significance Index: -0.0200 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0033
Cell Significance Index: -0.1400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0047
Cell Significance Index: -3.4800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0048
Cell Significance Index: -3.0600 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0050
Cell Significance Index: -2.2800 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0064
Cell Significance Index: -0.8200 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0084
Cell Significance Index: -0.1200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0088
Cell Significance Index: -1.2900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0100
Cell Significance Index: -0.6700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0104
Cell Significance Index: -0.6400 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0123
Cell Significance Index: -1.6900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0145
Cell Significance Index: -1.5100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0157
Cell Significance Index: -1.8300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0163
Cell Significance Index: -2.9400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0172
Cell Significance Index: -0.5500 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0174
Cell Significance Index: -0.3600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0177
Cell Significance Index: -1.8100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0179
Cell Significance Index: -2.1100 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0220
Cell Significance Index: -1.6900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0249
Cell Significance Index: -3.0600 - Cell Name: thymocyte (CL0000893)
Fold Change: -0.0261
Cell Significance Index: -0.3300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0281
Cell Significance Index: -0.7800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0295
Cell Significance Index: -1.3100 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0296
Cell Significance Index: -1.1200 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0302
Cell Significance Index: -1.8600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0323
Cell Significance Index: -1.8100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0369
Cell Significance Index: -1.7200 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0374
Cell Significance Index: -1.3100 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0392
Cell Significance Index: -1.1200 - Cell Name: common lymphoid progenitor (CL0000051)
Fold Change: -0.0399
Cell Significance Index: -0.4100 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0402
Cell Significance Index: -1.3200 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0405
Cell Significance Index: -1.2900 - Cell Name: common dendritic progenitor (CL0001029)
Fold Change: -0.0413
Cell Significance Index: -0.4300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0422
Cell Significance Index: -1.9900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0440
Cell Significance Index: -3.4900 - Cell Name: plasmablast (CL0000980)
Fold Change: -0.0469
Cell Significance Index: -0.4400 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: -0.0512
Cell Significance Index: -0.6700 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0521
Cell Significance Index: -1.3000 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.0522
Cell Significance Index: -1.6500 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0537
Cell Significance Index: -1.3800 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0543
Cell Significance Index: -1.0600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3050125868
Symbol: APOH_HUMAN
Name: Beta-2-glycoprotein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1650181
Title: Complete nucleotide and deduced amino acid sequence of human beta 2-glycoprotein I.
PubMed ID: 1650181
DOI: 10.1042/bj2770387
PubMed ID: 1655523
Title: Molecular cloning and mammalian expression of human beta 2-glycoprotein I cDNA.
PubMed ID: 1655523
PubMed ID: 1748314
Title: Nucleotide sequence and expression of the human gene encoding apolipoprotein H (beta 2-glycoprotein I).
PubMed ID: 1748314
PubMed ID: 1339416
Title: Molecular cloning and sequence analysis of the cDNA encoding human apolipoprotein H (beta 2-glycoprotein I).
PubMed ID: 1339416
DOI: 10.1007/bf02591656
PubMed ID: 1777418
Title: Molecular definition of human beta 2-glycoprotein I (beta 2-GPI) by cDNA cloning and inter-species differences of beta 2-GPI in alternation of anticardiolipin binding.
PubMed ID: 1777418
PubMed ID: 9914524
Title: Structure of the human beta2-glycoprotein I (apolipoprotein H) gene.
PubMed ID: 9914524
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 6587378
Title: Complete amino acid sequence of human plasma beta 2-glycoprotein I.
PubMed ID: 6587378
PubMed ID: 1602135
Title: Heterogeneity of anticardiolipin antibodies defined by the anticardiolipin cofactor.
PubMed ID: 1602135
PubMed ID: 2349221
Title: Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: beta 2-glycoprotein I (apolipoprotein H).
PubMed ID: 2349221
PubMed ID: 11250549
Title: Purification of apolipoprotein H (beta 2-glycoprotein I)-like protein from human follicular fluid.
PubMed ID: 11250549
PubMed ID: 1426288
Title: Activity, disulphide mapping and structural modelling of the fifth domain of human beta 2-glycoprotein I.
PubMed ID: 1426288
PubMed ID: 9155091
Title: Qualitative analysis of the carbohydrate composition of apolipoprotein H.
PubMed ID: 9155091
PubMed ID: 15084671
PubMed ID: 14760718
Title: Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.
PubMed ID: 14760718
PubMed ID: 16335952
Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.
PubMed ID: 16335952
DOI: 10.1021/pr0502065
PubMed ID: 16740002
Title: Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.
PubMed ID: 16740002
DOI: 10.1021/pr050492k
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 19139490
Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.
PubMed ID: 19139490
PubMed ID: 19838169
Title: Enrichment of glycopeptides for glycan structure and attachment site identification.
PubMed ID: 19838169
DOI: 10.1038/nmeth.1392
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 10508150
Title: Adhesion mechanism of human beta(2)-glycoprotein I to phospholipids based on its crystal structure.
PubMed ID: 10508150
PubMed ID: 10562535
Title: Crystal structure of human beta2-glycoprotein I: implications for phospholipid binding and the antiphospholipid syndrome.
PubMed ID: 10562535
PubMed ID: 8099061
Title: Human beta 2-glycoprotein I: molecular analysis of DNA and amino acid polymorphism.
PubMed ID: 8099061
DOI: 10.1007/bf00217367
PubMed ID: 9225969
Title: Molecular basis of the apolipoprotein H (beta 2-glycoprotein I) protein polymorphism.
PubMed ID: 9225969
PubMed ID: 9063752
Title: Identification of structural mutations in the fifth domain of apolipoprotein H (beta-2-glycoprotein I) which affect phospholipid binding.
PubMed ID: 9063752
DOI: 10.1093/hmg/6.2.311
Sequence Information:
- Length: 345
- Mass: 38298
- Checksum: 63101704F8EDFE3F
- Sequence:
MISPVLILFS SFLCHVAIAG RTCPKPDDLP FSTVVPLKTF YEPGEEITYS CKPGYVSRGG MRKFICPLTG LWPINTLKCT PRVCPFAGIL ENGAVRYTTF EYPNTISFSC NTGFYLNGAD SAKCTEEGKW SPELPVCAPI ICPPPSIPTF ATLRVYKPSA GNNSLYRDTA VFECLPQHAM FGNDTITCTT HGNWTKLPEC REVKCPFPSR PDNGFVNYPA KPTLYYKDKA TFGCHDGYSL DGPEEIECTK LGNWSAMPSC KASCKVPVKK ATVVYQGERV KIQEKFKNGM LHGDKVSFFC KNKEKKCSYT EDAQCIDGTI EVPKCFKEHS SLAFWKTDAS DVKPC
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.