APOH | ENSG00000091583 | NCBI 350

Details for: APOH

Gene ID: 350

Symbol: APOH

Ensembl ID: ENSG00000091583

Description: apolipoprotein H

Associated with

Hemostasis
(R-HSA-109582)
Platelet activation, signaling and aggregation
(R-HSA-76002)
Platelet degranulation
(R-HSA-114608)
Response to elevated platelet cytosolic ca2+
(R-HSA-76005)
Blood coagulation, intrinsic pathway
(GO:0007597)
Cell surface
(GO:0009986)
Chylomicron
(GO:0042627)
Collagen-containing extracellular matrix
(GO:0062023)
Extracellular exosome
(GO:0070062)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Heparin binding
(GO:0008201)
High-density lipoprotein particle
(GO:0034364)
Identical protein binding
(GO:0042802)
Lipid binding
(GO:0008289)
Lipoprotein lipase activator activity
(GO:0060230)
Negative regulation of angiogenesis
(GO:0016525)
Negative regulation of blood coagulation
(GO:0030195)
Negative regulation of endothelial cell migration
(GO:0010596)
Negative regulation of endothelial cell proliferation
(GO:0001937)
Negative regulation of fibrinolysis
(GO:0051918)
Negative regulation of myeloid cell apoptotic process
(GO:0033033)
Negative regulation of smooth muscle cell apoptotic process
(GO:0034392)
Phospholipid binding
(GO:0005543)
Plasminogen activation
(GO:0031639)
Platelet dense granule lumen
(GO:0031089)
Positive regulation of blood coagulation
(GO:0030194)
Positive regulation of lipoprotein lipase activity
(GO:0051006)
Protein binding
(GO:0005515)
Regulation of fibrinolysis
(GO:0051917)
Triglyceride metabolic process
(GO:0006641)
Triglyceride transport
(GO:0034197)
Very-low-density lipoprotein particle
(GO:0034361)

Other Information

Proteins

Beta-2-glycoprotein 1

Genular Protein ID: 3050125868

Symbol: APOH_HUMAN

Name: Beta-2-glycoprotein 1

UniProtKB Accession Codes:

P02749 B2R9M3 Q9UCN7

Database IDs:

Citations:

PubMed ID: 1650181

Title: Complete nucleotide and deduced amino acid sequence of human beta 2-glycoprotein I.

PubMed ID: 1650181

DOI: 10.1042/bj2770387

PubMed ID: 1655523

Title: Molecular cloning and mammalian expression of human beta 2-glycoprotein I cDNA.

PubMed ID: 1655523

DOI: 10.1016/0014-5793(91)81065-g

PubMed ID: 1748314

Title: Nucleotide sequence and expression of the human gene encoding apolipoprotein H (beta 2-glycoprotein I).

PubMed ID: 1748314

DOI: 10.1016/0378-1119(91)90449-l

PubMed ID: 1339416

Title: Molecular cloning and sequence analysis of the cDNA encoding human apolipoprotein H (beta 2-glycoprotein I).

PubMed ID: 1339416

DOI: 10.1007/bf02591656

PubMed ID: 1777418

Title: Molecular definition of human beta 2-glycoprotein I (beta 2-GPI) by cDNA cloning and inter-species differences of beta 2-GPI in alternation of anticardiolipin binding.

PubMed ID: 1777418

DOI: 10.1093/intimm/3.12.1217

PubMed ID: 9914524

Title: Structure of the human beta2-glycoprotein I (apolipoprotein H) gene.

PubMed ID: 9914524

DOI: 10.1046/j.1432-1327.1999.00063.x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 6587378

Title: Complete amino acid sequence of human plasma beta 2-glycoprotein I.

PubMed ID: 6587378

DOI: 10.1073/pnas.81.12.3640

PubMed ID: 1602135

Title: Heterogeneity of anticardiolipin antibodies defined by the anticardiolipin cofactor.

PubMed ID: 1602135

PubMed ID: 2349221

Title: Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: beta 2-glycoprotein I (apolipoprotein H).

PubMed ID: 2349221

DOI: 10.1073/pnas.87.11.4120

PubMed ID: 11250549

Title: Purification of apolipoprotein H (beta 2-glycoprotein I)-like protein from human follicular fluid.

PubMed ID: 11250549

DOI: 10.1016/s1096-4959(00)00359-6

PubMed ID: 1426288

Title: Activity, disulphide mapping and structural modelling of the fifth domain of human beta 2-glycoprotein I.

PubMed ID: 1426288

DOI: 10.1016/0014-5793(92)81442-o

PubMed ID: 9155091

Title: Qualitative analysis of the carbohydrate composition of apolipoprotein H.

PubMed ID: 9155091

DOI: 10.1023/a:1026378825391

PubMed ID: 15084671

Title: A proteomic analysis of human bile.

PubMed ID: 15084671

DOI: 10.1074/mcp.m400015-mcp200

PubMed ID: 14760718

Title: Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.

PubMed ID: 14760718

DOI: 10.1002/pmic.200300556

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 16740002

Title: Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.

PubMed ID: 16740002

DOI: 10.1021/pr050492k

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19139490

Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.

PubMed ID: 19139490

DOI: 10.1074/mcp.m800504-mcp200

PubMed ID: 19838169

Title: Enrichment of glycopeptides for glycan structure and attachment site identification.

PubMed ID: 19838169

DOI: 10.1038/nmeth.1392

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 10508150

Title: Adhesion mechanism of human beta(2)-glycoprotein I to phospholipids based on its crystal structure.

PubMed ID: 10508150

DOI: 10.1093/emboj/18.19.5166

PubMed ID: 10562535

Title: Crystal structure of human beta2-glycoprotein I: implications for phospholipid binding and the antiphospholipid syndrome.

PubMed ID: 10562535

DOI: 10.1093/emboj/18.22.6228

PubMed ID: 8099061

Title: Human beta 2-glycoprotein I: molecular analysis of DNA and amino acid polymorphism.

PubMed ID: 8099061

DOI: 10.1007/bf00217367

PubMed ID: 9225969

Title: Molecular basis of the apolipoprotein H (beta 2-glycoprotein I) protein polymorphism.

PubMed ID: 9225969

DOI: 10.1007/s004390050465

PubMed ID: 9063752

Title: Identification of structural mutations in the fifth domain of apolipoprotein H (beta-2-glycoprotein I) which affect phospholipid binding.

PubMed ID: 9063752

DOI: 10.1093/hmg/6.2.311

Sequence Information:

Length: 345
Mass: 38298
Checksum: 63101704F8EDFE3F
Sequence:

MISPVLILFS SFLCHVAIAG RTCPKPDDLP FSTVVPLKTF YEPGEEITYS CKPGYVSRGG 
MRKFICPLTG LWPINTLKCT PRVCPFAGIL ENGAVRYTTF EYPNTISFSC NTGFYLNGAD 
SAKCTEEGKW SPELPVCAPI ICPPPSIPTF ATLRVYKPSA GNNSLYRDTA VFECLPQHAM 
FGNDTITCTT HGNWTKLPEC REVKCPFPSR PDNGFVNYPA KPTLYYKDKA TFGCHDGYSL 
DGPEEIECTK LGNWSAMPSC KASCKVPVKK ATVVYQGERV KIQEKFKNGM LHGDKVSFFC 
KNKEKKCSYT EDAQCIDGTI EVPKCFKEHS SLAFWKTDAS DVKPC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: APOH

Associated with

Other Information

Complete nucleotide and deduced amino acid sequence of human beta 2-glycoprotein I. PubMed ID: 1650181

Molecular cloning and mammalian expression of human beta 2-glycoprotein I cDNA. PubMed ID: 1655523

Nucleotide sequence and expression of the human gene encoding apolipoprotein H (beta 2-glycoprotein I). PubMed ID: 1748314

Molecular cloning and sequence analysis of the cDNA encoding human apolipoprotein H (beta 2-glycoprotein I). PubMed ID: 1339416

Molecular definition of human beta 2-glycoprotein I (beta 2-GPI) by cDNA cloning and inter-species differences of beta 2-GPI in alternation of anticardiolipin binding. PubMed ID: 1777418

Structure of the human beta2-glycoprotein I (apolipoprotein H) gene. PubMed ID: 9914524

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Complete amino acid sequence of human plasma beta 2-glycoprotein I. PubMed ID: 6587378

Heterogeneity of anticardiolipin antibodies defined by the anticardiolipin cofactor. PubMed ID: 1602135

Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: beta 2-glycoprotein I (apolipoprotein H). PubMed ID: 2349221

Purification of apolipoprotein H (beta 2-glycoprotein I)-like protein from human follicular fluid. PubMed ID: 11250549

Activity, disulphide mapping and structural modelling of the fifth domain of human beta 2-glycoprotein I. PubMed ID: 1426288

Qualitative analysis of the carbohydrate composition of apolipoprotein H. PubMed ID: 9155091

A proteomic analysis of human bile. PubMed ID: 15084671

Screening for N-glycosylated proteins by liquid chromatography mass spectrometry. PubMed ID: 14760718

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. PubMed ID: 16335952

Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry. PubMed ID: 16740002

Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. PubMed ID: 19159218

A strategy for precise and large scale identification of core fucosylated glycoproteins. PubMed ID: 19139490

Enrichment of glycopeptides for glycan structure and attachment site identification. PubMed ID: 19838169

Initial characterization of the human central proteome. PubMed ID: 21269460

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

Adhesion mechanism of human beta(2)-glycoprotein I to phospholipids based on its crystal structure. PubMed ID: 10508150

Crystal structure of human beta2-glycoprotein I: implications for phospholipid binding and the antiphospholipid syndrome. PubMed ID: 10562535

Human beta 2-glycoprotein I: molecular analysis of DNA and amino acid polymorphism. PubMed ID: 8099061

Molecular basis of the apolipoprotein H (beta 2-glycoprotein I) protein polymorphism. PubMed ID: 9225969

Identification of structural mutations in the fifth domain of apolipoprotein H (beta-2-glycoprotein I) which affect phospholipid binding. PubMed ID: 9063752