Phlpp | FBgn0032749 | NCBI 35178

Details for: Phlpp

Gene ID: 35178

Symbol: Phlpp

Ensembl ID: FBgn0032749

Description: PH domain leucine-rich repeat protein phosphatase

Associated with

Gene expression (transcription)
(R-DME-74160)
Generic transcription pathway
(R-DME-212436)
Intracellular signaling by second messengers
(R-DME-9006925)
Negative regulation of the pi3k/akt network
(R-DME-199418)
Pip3 activates akt signaling
(R-DME-1257604)
Rna polymerase ii transcription
(R-DME-73857)
Tp53 regulates transcription of caspase activators and caspases
(R-DME-6803207)
Tp53 regulates transcription of cell death genes
(R-DME-5633008)
Transcriptional regulation by tp53
(R-DME-3700989)
Cytoplasm
(GO:0005737)
Protein binding
(GO:0005515)
Protein dephosphorylation
(GO:0006470)
Protein serine/threonine phosphatase activity
(GO:0004722)
Regulation of apoptotic process
(GO:0042981)
Signal transduction
(GO:0007165)

Other Information

Proteins

Protein phosphatase PHLPP-like protein

Genular Protein ID: 3995877117

Symbol: PHLPP_DROME

Name: Protein phosphatase PHLPP-like protein

UniProtKB Accession Codes:

Q9VJ07

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 15808505

Title: PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth.

PubMed ID: 15808505

DOI: 10.1016/j.molcel.2005.03.008

Sequence Information:

Length: 954
Mass: 107092
Checksum: 7ADCF6F54F15957A
Sequence:

MLKATRKQAD PYKSKLKVSA SHSGPHPLPV EVTAAEEEQA ATFGQTSPQK LSLKGSQLGG 
SILIGNYNYL TQLEVCENEM EVLDLSSLAQ LETLKCSRNK LMELIINGTN LQTLVADHNY 
LHNISTTNTH PVPLKLQRID ISHNNFSELP NWVGACASLT AINASHNRLN NVAVLLRNYR 
ITELVSLDLA YNDLKQLDQF PEGFSSIRSL QLQSNELPSL PDNFFAVTHA RLETLNVSCN 
KLSTLPRYEQ NNHAALVNLS LAGNHLNDSI FEPLHNAAKL RVLHLAYNRI GVLPAACVRN 
WPELEILVLS GNMLQQLPEE VATLGQLRVL RCCNNLLLCT PQLAKLAMLK VLDLSHNHLD 
RVNLLALVPS RNLKYLDLSG NLQLQVDEQQ FKVCQSQSQR HWSLVDVSGN NRAALPTTKI 
RQVSAQRNQN KTSGPWTMGF AETPGSGDCR KLSVYQLRAA NYGGSDEALY GMFEALEGRG 
RAAQEMSHLV PDLMKQEQMV KDSAVRDYMK FTLLAAQQQC GSVRSAALFH LTRTRAPSKV 
RPLKSKRYVL RMASTGGLDA YLIRRTSQLR LTKPDVIQKD QIHSMPDPHV LELILSNDDE 
YLVVGNAQLW SVMDIDRAAR EIRKEENSLL AAKRLVDIAQ SFAAAESLSV IVVRFRHLGT 
DVDHLIRELK QSVRKKPQPV SLPLSSGSVC KRTCCDRSNA CRHRAIEQEP LAGRSSPSGQ 
SDRDLLAKDK DDEFVLAHAR VLQEEQQLEM LDETESVSES VLSEEQFKCW EYMLEQNTQL 
LFDKELNTIS KSFTKQRTVP NAIMAATVLP ERNDFTSNLM RTVTNKFIST STPQLPQPIT 
TSVPLGSYHQ VKQAPPGHFG SALSFQQAHS YGYNLFDAKP RPKFHGGTVK RSAGPNSAYF 
GSLQRLMPYN FEYDFAVTQE RERNILDEEE HDDDDFNEHE SRMRKYWGVA TTEL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.