spi | FBgn0005672 | NCBI 35253

Details for: spi

Gene ID: 35253

Symbol: spi

Ensembl ID: FBgn0005672

Description: spitz

Associated with

Behavioral response to ethanol
(GO:0048149)
Border follicle cell migration
(GO:0007298)
Cell surface receptor signaling pathway
(GO:0007166)
Determination of genital disc primordium
(GO:0035225)
Dorsal closure
(GO:0007391)
Ectodermal cell fate determination
(GO:0001713)
Endoplasmic reticulum
(GO:0005783)
Epidermal growth factor receptor binding
(GO:0005154)
Epidermal growth factor receptor signaling pathway
(GO:0007173)
Epithelial cell proliferation involved in malpighian tubule morphogenesis
(GO:0061331)
Extracellular space
(GO:0005615)
Heart process
(GO:0003015)
Imaginal disc-derived wing morphogenesis
(GO:0007476)
Membrane
(GO:0016020)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of gene expression
(GO:0010629)
Oenocyte development
(GO:0007438)
Olfactory learning
(GO:0008355)
Ommatidial rotation
(GO:0016318)
Peripheral nervous system development
(GO:0007422)
Photoreceptor cell differentiation
(GO:0046530)
Photoreceptor cell fate determination
(GO:0043703)
Positive regulation of border follicle cell migration
(GO:1903688)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of neurogenesis
(GO:0050769)
Protein binding
(GO:0005515)
Receptor ligand activity
(GO:0048018)
Spiracle morphogenesis, open tracheal system
(GO:0035277)
Stem cell fate commitment
(GO:0048865)
Stomatogastric nervous system development
(GO:0007421)
Transmembrane receptor protein tyrosine kinase activator activity
(GO:0030297)

Other Information

Proteins

Protein spitz

Genular Protein ID: 2791402400

Symbol: SPITZ_DROME

Name: Protein spitz

UniProtKB Accession Codes:

Q01083 Q8SXE0 Q9VIT4

Database IDs:

Citations:

PubMed ID: 1644292

Title: The Drosophila spitz gene encodes a putative EGF-like growth factor involved in dorsal-ventral axis formation and neurogenesis.

PubMed ID: 1644292

DOI: 10.1101/gad.6.8.1503

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 7833286

Title: The spitz gene is required for photoreceptor determination in the Drosophila eye where it interacts with the EGF receptor.

PubMed ID: 7833286

DOI: 10.1016/0925-4773(94)90003-5

PubMed ID: 11672524

Title: Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila.

PubMed ID: 11672524

DOI: 10.1016/s0092-8674(01)00526-8

PubMed ID: 11790319

Title: EGF receptor signalling: roles of Star and Rhomboid revealed.

PubMed ID: 11790319

DOI: 10.1016/s0960-9822(01)00642-x

PubMed ID: 18500331

Title: Structural basis for EGFR ligand sequestration by Argos.

PubMed ID: 18500331

DOI: 10.1038/nature06978

Sequence Information:

Length: 234
Mass: 26424
Checksum: 237F7A3B03DBD685
Sequence:

MHSTMSVQHG LVALVLIGCL AHPWHVEACS SRTVPKPRSS ISSSMSGTAL PPTQAPVTSS 
TTMRTTTTTT PRPNITFPTY KCPETFDAWY CLNDAHCFAV KIADLPVYSC ECAIGFMGQR 
CEYKEIDNTY LPKRPRPMLE KASIASGAMC ALVFMLFVCL AFYLRFEQRA AKKAYELEQE 
LQQEYDDDDG QCECCRNRCC PDGQEPVILE RKLPYHMRLE HALMSFAIRR SNKL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: spi

Associated with

Other Information

The Drosophila spitz gene encodes a putative EGF-like growth factor involved in dorsal-ventral axis formation and neurogenesis. PubMed ID: 1644292

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila full-length cDNA resource. PubMed ID: 12537569

The spitz gene is required for photoreceptor determination in the Drosophila eye where it interacts with the EGF receptor. PubMed ID: 7833286

Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila. PubMed ID: 11672524

EGF receptor signalling: roles of Star and Rhomboid revealed. PubMed ID: 11790319

Structural basis for EGFR ligand sequestration by Argos. PubMed ID: 18500331