Details for: tsh

Gene ID: 35430

Symbol: tsh

Ensembl ID: FBgn0003866

Description: teashirt

Associated with

  • Compound eye development
    (GO:0048749)
  • Cytoplasm
    (GO:0005737)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna binding
    (GO:0003677)
  • Dorsal/ventral pattern formation, imaginal disc
    (GO:0007450)
  • Epidermis morphogenesis
    (GO:0048730)
  • Eye-antennal disc development
    (GO:0035214)
  • Head involution
    (GO:0008258)
  • Imaginal disc-derived wing morphogenesis
    (GO:0007476)
  • Leg disc proximal/distal pattern formation
    (GO:0007479)
  • Malpighian tubule stellate cell differentiation
    (GO:0061330)
  • Midgut development
    (GO:0007494)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of salivary gland boundary specification
    (GO:0045705)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleus
    (GO:0005634)
  • Positive regulation of cell proliferation involved in compound eye morphogenesis
    (GO:2000497)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Regulation of gene expression
    (GO:0010468)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Specification of segmental identity, head
    (GO:0007380)
  • Specification of segmental identity, thorax
    (GO:0007384)
  • Specification of segmental identity, trunk
    (GO:0035292)
  • Wing disc proximal/distal pattern formation
    (GO:0007473)
  • Wnt signaling pathway
    (GO:0016055)

Other Information

Genular Protein ID: 3782312122

Symbol: TSH_DROME

Name: Protein teashirt

UniProtKB Accession Codes:

P22265 A8E6H0 Q6AWP7 Q7KRS3 Q9V9Q0

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 4 EnsemblMetazoa 1 FlyBase 1 GO 27 Gene3D 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 2 PhylomeDB 1 Proteomes 1 Reactome 1 RefSeq 1 SAM 1 SMART 1 STRING 1 SUPFAM 1 SignaLink 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 1846092

Title: The gene teashirt is required for the development of Drosophila embryonic trunk segments and encodes a protein with widely spaced zinc finger motifs.

PubMed ID: 1846092

DOI: 10.1016/0092-8674(91)90209-h

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 1360402

Title: The role of the teashirt gene in trunk segmental identity in Drosophila.

PubMed ID: 1360402

DOI: 10.1242/dev.115.4.1017

PubMed ID: 7925029

Title: Homeotic complex and teashirt genes co-operate to establish trunk segmental identities in Drosophila.

PubMed ID: 7925029

DOI: 10.1242/dev.120.8.2287

PubMed ID: 7607071

Title: Role of the teashirt gene in Drosophila midgut morphogenesis: secreted proteins mediate the action of homeotic genes.

PubMed ID: 7607071

DOI: 10.1242/dev.120.10.2799

PubMed ID: 8951796

Title: The Drosophila teashirt homeotic protein is a DNA-binding protein and modulo, a HOM-C regulated modifier of variegation, is a likely candidate for being a direct target gene.

PubMed ID: 8951796

DOI: 10.1016/0925-4773(96)00594-1

PubMed ID: 9707400

Title: Trunk-specific modulation of wingless signalling in Drosophila by teashirt binding to armadillo.

PubMed ID: 9707400

DOI: 10.1016/s0960-9822(07)00369-7

PubMed ID: 10842058

Title: Proximal distal axis formation in the Drosophila leg: distinct functions of teashirt and homothorax in the proximal leg.

PubMed ID: 10842058

DOI: 10.1016/s0925-4773(00)00311-7

PubMed ID: 11429289

Title: Identification of a regulatory allele of teashirt (tsh) in Drosophila melanogaster that affects wing hinge development. An adult-specific tsh enhancer in Drosophila.

PubMed ID: 11429289

DOI: 10.1016/s0925-4773(01)00397-5

PubMed ID: 15110046

Title: Dorso-ventral asymmetric functions of teashirt in Drosophila eye development depend on spatial cues provided by early DV patterning genes.

PubMed ID: 15110046

DOI: 10.1016/j.mod.2004.02.005

PubMed ID: 15936749

Title: A critical role of teashirt for patterning the ventral epidermis is masked by ectopic expression of tiptop, a paralog of teashirt in Drosophila.

PubMed ID: 15936749

DOI: 10.1016/j.ydbio.2005.05.005

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

Sequence Information:

  • Length: 954
  • Mass: 100651
  • Checksum: 33FB3677DC8C4B33
  • Sequence:
    • MLHEALMLEI YRQALNAGAL PTARPRSTES ANSSERCPSH DSNSSEHGGG AGSGGVGHRL 
DAAALSTGVM PGEGPTTLHS SFPAVPQSLP SQPPSMEAYL HMVAAAAQQY GFPLAAAAAA 
GAGPRLPLPL ANEAAAPFKL PPQASPTASS NNSEALDFRT NLYGRAESAE PPASEGEEEE 
FDDGANNPLD LSVGTRKRGH ESEPQLGHIQ VKKMFKSDSP PANSVASPSA SQLLPGVNPY 
LAAVAAANIF RAGQFPDWNS KNDLVVDPLE KMSDIVKGGA SGMGTKEKMH SSKATTPQAA 
SQPPKSPVQP TPNQNSESGG GSGGGAAGSG AVTKARHNIW QSHWQNKGVA SSVFRCVWCK 
QSFPTLEALT THMKDSKHCG VNVPPFGNLP SNNPQPQHHH PTPPPPPQNH NLRKHSSGSA 
SNHSPSANVK NAFQYRGDPP TPLPRKLVRG QNVWLGKGVE QAMQILKCMR CGESFRSLGE 
MTKHMQETQH YTNILSQEQS ISIKSGNANA NSDAKESHNS LSSEESRTLS AVLTCKVCDK 
AFNSLGDLSN HMAKNNHYAE PLLQSAGARK RPAPKKREKS LPVRKLLEMK GGSGTTQEDH 
SNEKTSVQGK PGLGPGGGDK NDAALFAERM RQYITGVKAP EEIAKVAAAQ LLAKNKSPEL 
VEQKNGGSAK AAGASSVLSA IEQMFTTSFD TPPRHASLPA SSPSNSSTKN TSPVASSILK 
RLGIDETVDY NKPLIDTNDP YYQHYRYTSS ERSGSECSAE ARPRLDAPTP EKQQQGGGHD 
EESSKPAIKQ EREAESKPVK MEIKSEFVDE PNEAEETSKM EAAVVNGSAT NNNNNIVERS 
SPKTPSSAAS PQTRLLPPRS PAESQRSVTP KSPASSHKSY DGSSEGTKKF PSDSLNALSS 
MFDSLGSSGA GANSRAKLAA AAAAGGSESP ENLTAGGNSL AALRQFCVKK EKTA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.