Details for: Clamp

Gene ID: 35445

Symbol: Clamp

Ensembl ID: FBgn0032979

Description: Chromatin-linked adaptor for MSL proteins

Associated with

Other Information

Genular Protein ID: 1449437594

Symbol: CLAMP_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 23873939

Title: The CLAMP protein links the MSL complex to the X chromosome during Drosophila dosage compensation.

PubMed ID: 23873939

DOI: 10.1101/gad.214585.113

PubMed ID: 27414415

Title: Expansion of GA dinucleotide repeats increases the density of CLAMP binding sites on the X-chromosome to promote Drosophila dosage compensation.

PubMed ID: 27414415

DOI: 10.1371/journal.pgen.1006120

PubMed ID: 27995349

Title: The essential Drosophila CLAMP protein differentially regulates non-coding roX RNAs in male and females.

PubMed ID: 27995349

DOI: 10.1007/s10577-016-9541-9

PubMed ID: 28838946

Title: Histone locus regulation by the Drosophila dosage compensation adaptor protein CLAMP.

PubMed ID: 28838946

DOI: 10.1101/gad.300855.117

PubMed ID: 29077765

Title: Enhanced chromatin accessibility of the dosage compensated Drosophila male X-chromosome requires the CLAMP zinc finger protein.

PubMed ID: 29077765

DOI: 10.1371/journal.pone.0186855

PubMed ID: 29281702

Title: The Drosophila CLAMP protein associates with diverse proteins on chromatin.

PubMed ID: 29281702

DOI: 10.1371/journal.pone.0189772

PubMed ID: 31320325

Title: The simultaneous interaction of MSL2 with CLAMP and DNA provides redundancy in the initiation of dosage compensation in Drosophila males.

PubMed ID: 31320325

DOI: 10.1242/dev.179663

PubMed ID: 30718365

Title: The zinc-finger protein CLAMP promotes gypsy chromatin insulator function in Drosophila.

PubMed ID: 30718365

DOI: 10.1242/jcs.226092

PubMed ID: 34342574

Title: CLAMP and Zelda function together to promote Drosophila zygotic genome activation.

PubMed ID: 34342574

DOI: 10.7554/elife.69937

PubMed ID: 34187599

Title: The zinc finger protein CLAMP promotes long-range chromatin interactions that mediate dosage compensation of the Drosophila male X-chromosome.

PubMed ID: 34187599

DOI: 10.1186/s13072-021-00399-3

PubMed ID: 34849887

Title: CLAMP regulates zygotic genome activation in Drosophila embryos.

PubMed ID: 34849887

DOI: 10.1093/genetics/iyab107

PubMed ID: 35409222

Title: Dimerization activity of a disordered N-terminal domain from Drosophila CLAMP protein.

PubMed ID: 35409222

DOI: 10.3390/ijms23073862

PubMed ID: 37602401

Title: Physical interaction between MSL2 and CLAMP assures direct cooperativity and prevents competition at composite binding sites.

PubMed ID: 37602401

DOI: 10.1093/nar/gkad680

PubMed ID: 35648444

Title: Structural basis for interaction between CLAMP and MSL2 proteins involved in the specific recruitment of the dosage compensation complex in Drosophila.

PubMed ID: 35648444

DOI: 10.1093/nar/gkac455

Sequence Information:

  • Length: 561
  • Mass: 61195
  • Checksum: 76361917461BD34F
  • Sequence:
  • MEDLTKNIIF TNAINGQPAT IQYQTADGTI LKQPKIEGQK TEQQPTFYYT TNGNGGTVNL 
    AQLATTDDNK TCYIAQPVGG YNYALVNGMP LNQGAALGIA TVDAQGRIQI VNQNKPIAAN 
    TISNISFKCD VCSDMFPHLA LLNAHKRMHT DGEQQQQQQH NAQAGGDSIA VVSAQGLVQA 
    QNIIGNGQMG QIQIVSSDTL EPVQQSVMQQ QQHESKASKC INCGSSMLQQ SKRKGPKQVR 
    CESCMQAEQT AQQQQQLFVA QDGQMAHPVQ IISTTPQAQA QLQQIVAAQT GGTTPKREAS 
    SGSGHHPVKK RNSQQMTKCQ KCNGSGVVLV GQHSHASHSG VGGSVKQSVT VKTENPSKPF 
    SCNICGGLFS RYSSLWSHKK LHSGEKNYKC SICGLAFAKA VYLKNHARIH TGEKPYKCQT 
    CGMQFSQSPH LKNHERTHSG ERPYVCGVCD KGFARHATLW NHRRIHTGEK PYKCEICGSA 
    FSQAAHLKNH AKVHSGEKPY KCEICSAAFA DRFALKRHRG IHQKYGQTAP RQTSSDGMIV 
    HKQEIPDMED EAQQEVIIGG L

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.