Details for: FAS
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.58
Marker Score: 53774 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 1.58
Marker Score: 2587 - Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 168482 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 1.35
Marker Score: 1148 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.33
Marker Score: 3260 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 1.22
Marker Score: 7799 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 1.12
Marker Score: 4155 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 1.1
Marker Score: 459 - Cell Name: fibroblast of connective tissue of prostate (CL1000299)
Fold Change: 1.07
Marker Score: 267 - Cell Name: prostate stromal cell (CL0002622)
Fold Change: 1.06
Marker Score: 267 - Cell Name: fibroblast of lung (CL0002553)
Fold Change: 1.05
Marker Score: 2740 - Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 1.04
Marker Score: 5126 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71739 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47963 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30399 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2401 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.94
Marker Score: 484 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.93
Marker Score: 440 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2713 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.89
Marker Score: 357 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.88
Marker Score: 1781 - Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 0.87
Marker Score: 3735 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.87
Marker Score: 312 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5251 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.85
Marker Score: 4868 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 0.84
Marker Score: 2362 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.83
Marker Score: 919 - Cell Name: mature T cell (CL0002419)
Fold Change: 0.83
Marker Score: 8197 - Cell Name: exhausted T cell (CL0011025)
Fold Change: 0.81
Marker Score: 468 - Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
Fold Change: 0.8
Marker Score: 584 - Cell Name: naive regulatory T cell (CL0002677)
Fold Change: 0.8
Marker Score: 242 - Cell Name: type I pneumocyte (CL0002062)
Fold Change: 0.78
Marker Score: 942 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.78
Marker Score: 594 - Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: 0.78
Marker Score: 241 - Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
Fold Change: 0.77
Marker Score: 553 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 0.75
Marker Score: 418 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.75
Marker Score: 1218 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.75
Marker Score: 15912 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.73
Marker Score: 378 - Cell Name: regulatory T cell (CL0000815)
Fold Change: 0.73
Marker Score: 803 - Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
Fold Change: 0.72
Marker Score: 424 - Cell Name: type I NK T cell (CL0000921)
Fold Change: 0.72
Marker Score: 566 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 0.72
Marker Score: 411 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 0.72
Marker Score: 765 - Cell Name: early promyelocyte (CL0002154)
Fold Change: 0.71
Marker Score: 570 - Cell Name: brush cell (CL0002204)
Fold Change: 0.71
Marker Score: 648 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.69
Marker Score: 10864 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.69
Marker Score: 4155 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.69
Marker Score: 2893 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.68
Marker Score: 2944 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.68
Marker Score: 173 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 0.67
Marker Score: 35482 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.67
Marker Score: 702 - Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
Fold Change: 0.67
Marker Score: 1306 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 0.67
Marker Score: 1637 - Cell Name: stromal cell (CL0000499)
Fold Change: 0.66
Marker Score: 772 - Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
Fold Change: 0.65
Marker Score: 612 - Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
Fold Change: 0.65
Marker Score: 944 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.64
Marker Score: 732 - Cell Name: myofibroblast cell (CL0000186)
Fold Change: 0.63
Marker Score: 776 - Cell Name: double negative T regulatory cell (CL0011024)
Fold Change: 0.62
Marker Score: 603 - Cell Name: blood cell (CL0000081)
Fold Change: 0.62
Marker Score: 7239 - Cell Name: Unknown (CL0000548)
Fold Change: 0.62
Marker Score: 452 - Cell Name: T follicular helper cell (CL0002038)
Fold Change: 0.62
Marker Score: 511 - Cell Name: bronchus fibroblast of lung (CL2000093)
Fold Change: 0.61
Marker Score: 843 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.61
Marker Score: 9754 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 0.61
Marker Score: 192 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 0.6
Marker Score: 1159.5 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.6
Marker Score: 598.5 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.6
Marker Score: 285 - Cell Name: adventitial cell (CL0002503)
Fold Change: 0.59
Marker Score: 146 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 0.59
Marker Score: 4367 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.59
Marker Score: 1379 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 0.58
Marker Score: 368.5 - Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 0.58
Marker Score: 486 - Cell Name: secretory cell (CL0000151)
Fold Change: 0.56
Marker Score: 1026 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.56
Marker Score: 380 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.55
Marker Score: 441 - Cell Name: basal cell (CL0000646)
Fold Change: 0.55
Marker Score: 711 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.55
Marker Score: 177 - Cell Name: stem cell of epidermis (CL1000428)
Fold Change: 0.55
Marker Score: 185 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.54
Marker Score: 2278 - Cell Name: centrocyte (CL0009111)
Fold Change: 0.54
Marker Score: 128 - Cell Name: mucosal invariant T cell (CL0000940)
Fold Change: 0.53
Marker Score: 475 - Cell Name: fibroblast (CL0000057)
Fold Change: 0.53
Marker Score: 515 - Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
Fold Change: 0.53
Marker Score: 572 - Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 0.52
Marker Score: 565 - Cell Name: mammary gland epithelial cell (CL0002327)
Fold Change: 0.52
Marker Score: 184 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.51
Marker Score: 306 - Cell Name: progenitor cell of endocrine pancreas (CL0002351)
Fold Change: 0.51
Marker Score: 111 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 0.51
Marker Score: 633 - Cell Name: Schwann cell (CL0002573)
Fold Change: 0.51
Marker Score: 176 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 0.51
Marker Score: 399 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.5
Marker Score: 28056 - Cell Name: dendritic cell (CL0000451)
Fold Change: 0.5
Marker Score: 344 - Cell Name: mesothelial cell (CL0000077)
Fold Change: 0.5
Marker Score: 201 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.5
Marker Score: 202 - Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
Fold Change: 0.5
Marker Score: 305 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.49
Marker Score: 490 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.49
Marker Score: 5539
Hover over a box to see details here...
Hover over a box to see details here...
Hover over a box to see details here...
Other Information
Genular Protein ID: 3288833186
Symbol: TNR6_HUMAN
Name: Tumor necrosis factor receptor superfamily member 6
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1713127
Title: The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis.
PubMed ID: 1713127
PubMed ID: 1375228
Title: Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen.
PubMed ID: 1375228
PubMed ID: 7575433
Title: Differential expression of human Fas mRNA species upon peripheral blood mononuclear cell activation.
PubMed ID: 7575433
DOI: 10.1042/bj3100957
PubMed ID: 7533181
Title: Three functional soluble forms of the human apoptosis-inducing Fas molecule are produced by alternative splicing.
PubMed ID: 7533181
PubMed ID: 8598453
Title: Fas/Apo-1 (CD95) receptor lacking the intracytoplasmic signaling domain protects tumor cells from Fas-mediated apoptosis.
PubMed ID: 8598453
PubMed ID: 8648105
Title: An N-terminal domain shared by Fas/Apo-1 (CD95) soluble variants prevents cell death in vitro.
PubMed ID: 8648105
PubMed ID: 17336828
Title: Autoimmune lymphoproliferative syndrome (ALPS) in a patient with a new germline Fas gene mutation.
PubMed ID: 17336828
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7538908
Title: RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death.
PubMed ID: 7538908
PubMed ID: 10542291
Title: F1Aalpha, a death receptor-binding protein homologous to the Caenorhabditis elegans sex-determining protein, FEM-1, is a caspase substrate that mediates apoptosis.
PubMed ID: 10542291
PubMed ID: 10535980
Title: LFG: an anti-apoptotic gene that provides protection from fas-mediated cell death.
PubMed ID: 10535980
PubMed ID: 14759258
PubMed ID: 15465831
Title: A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway.
PubMed ID: 15465831
PubMed ID: 18846110
Title: Identification of an antiapoptotic protein complex at death receptors.
PubMed ID: 18846110
DOI: 10.1038/cdd.2008.124
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 21109225
Title: Whole-exome-sequencing-based discovery of human FADD deficiency.
PubMed ID: 21109225
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22171320
Title: Human urinary glycoproteomics; attachment site specific analysis of N- and O-linked glycosylations by CID and ECD.
PubMed ID: 22171320
PubMed ID: 23955153
Title: Pathogen blocks host death receptor signalling by arginine GlcNAcylation of death domains.
PubMed ID: 23955153
DOI: 10.1038/nature12436
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25301068
Title: Fas palmitoylation by the palmitoyl acyltransferase DHHC7 regulates Fas stability.
PubMed ID: 25301068
DOI: 10.1038/cdd.2014.153
PubMed ID: 30979585
Title: Structural and functional insights into host death domains inactivation by the bacterial arginine GlcNAcyltransferase effector.
PubMed ID: 30979585
PubMed ID: 8967952
Title: NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain.
PubMed ID: 8967952
DOI: 10.1038/384638a0
PubMed ID: 19118384
Title: The Fas-FADD death domain complex structure unravels signalling by receptor clustering.
PubMed ID: 19118384
DOI: 10.1038/nature07606
PubMed ID: 24914971
Title: Structural insights into the mechanism of calmodulin binding to death receptors.
PubMed ID: 24914971
PubMed ID: 7540117
Title: Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome.
PubMed ID: 7540117
PubMed ID: 8929361
Title: Fas gene mutations in the Canale-Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmunity.
PubMed ID: 8929361
PubMed ID: 9028321
Title: Missense mutations in the Fas gene resulting in autoimmune lymphoproliferative syndrome: a molecular and immunological analysis.
PubMed ID: 9028321
PubMed ID: 9028957
Title: Clinical, immunologic, and genetic features of an autoimmune lymphoproliferative syndrome associated with abnormal lymphocyte apoptosis.
PubMed ID: 9028957
PubMed ID: 9322534
Title: Fas/Apo1 mutations and autoimmune lymphoproliferative syndrome in a patient with type 2 autoimmune hepatitis.
PubMed ID: 9322534
PubMed ID: 9787134
Title: Somatic Fas mutations in non-Hodgkin's lymphoma: association with extranodal disease and autoimmunity.
PubMed ID: 9787134
PubMed ID: 9821419
Title: The clinical spectrum in a large kindred with autoimmune lymphoproliferative syndrome caused by a Fas mutation that impairs lymphocyte apoptosis.
PubMed ID: 9821419
PubMed ID: 10090885
Title: Autoimmune lymphoproliferative syndrome with defective Fas: genotype influences penetrance.
PubMed ID: 10090885
DOI: 10.1086/302333
PubMed ID: 10515860
Title: Lymphoproliferative syndrome with autoimmunity: A possible genetic basis for dominant expression of the clinical manifestations.
PubMed ID: 10515860
PubMed ID: 10340403
Title: Defective apoptosis due to a point mutation in the death domain of CD95 associated with autoimmune lymphoproliferative syndrome, T-cell lymphoma, and Hodgkin's disease.
PubMed ID: 10340403
PubMed ID: 9927496
Title: The molecular basis for apoptotic defects in patients with CD95 (Fas/Apo-1) mutations.
PubMed ID: 9927496
DOI: 10.1172/jci5121
PubMed ID: 10620127
Title: Somatic mutations of Fas (Apo-1/CD95) gene in cutaneous squamous cell carcinoma arising from a burn scar.
PubMed ID: 10620127
PubMed ID: 11418480
Title: The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis.
PubMed ID: 11418480
PubMed ID: 20935634
Title: The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations.
PubMed ID: 20935634
DOI: 10.1038/nsmb.1920
Sequence Information:
- Length: 335
- Mass: 37732
- Checksum: 0139942535111410
- Sequence:
MLGIWTLLPL VLTSVARLSS KSVNAQVTDI NSKGLELRKT VTTVETQNLE GLHHDGQFCH KPCPPGERKA RDCTVNGDEP DCVPCQEGKE YTDKAHFSSK CRRCRLCDEG HGLEVEINCT RTQNTKCRCK PNFFCNSTVC EHCDPCTKCE HGIIKECTLT SNTKCKEEGS RSNLGWLCLL LLPIPLIVWV KRKEVQKTCR KHRKENQGSH ESPTLNPETV AINLSDVDLS KYITTIAGVM TLSQVKGFVR KNGVNEAKID EIKNDNVQDT AEQKVQLLRN WHQLHGKKEA YDTLIKDLKK ANLCTLAEKI QTIILKDITS DSENSNFRNE IQSLV
Genular Protein ID: 1211796270
Symbol: Q59FU8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
Sequence Information:
- Length: 362
- Mass: 40494
- Checksum: F4FB186BFD5D8EE2
- Sequence:
MLRVCAQGWH AQGLPHGTNS LLKGGTETSL STPTRLVVLT SVARLSSKSV NAQVTDINSK GLELRKTVTT VETQNLEGLH HDGQFCHKPC PPGERKARDC TVNGDEPDCV PCQEGKEYTD KAHFSSKCRR CRLCDEGHGL EVEINCTRTQ NTKCRCKPNF FCNSTVCEHC DPCTKCEHGI IKECTLTSNT KCKEEGSRSN LGWLCLLLLP IPLIVWVKRK EVQKTCRKHR KENQGSHESP TLNPETVAIN LSDVDLSKYI TTIAGVMTLS QVKGFVRKNG VNEAKIDEIK NDNVQDTAEQ KVQLLRNWHQ LHGKKEAYDT LIKDLKKANL CTLAEKIQTI ILKDITSDSE NSNFRNEIQS LV
Genular Protein ID: 2968375444
Symbol: K9J972_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
Sequence Information:
- Length: 197
- Mass: 21955
- Checksum: 343DA9D7F00C3B8A
- Sequence:
MLGIWTLLPL VLTSVARLSS KSVNAQVTDI NSKGLELRKT VTTVETQNLE GLHHDGQFCH KPCPPGERKA RDCTVNGDEP DCVPCQEGKE YTDKAHFSSK CRRCRLCDEG HGLEVEINCT RTQNTKCRCK PNFFCNSTVC EHCDPCTKCE HGIIKECTLT SNTKCKEEGS RSNLGWLCLL LLPIPLIVWG NSGNKFI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.