dpa | FBgn0015929 | NCBI 35679

Details for: dpa

Gene ID: 35679

Symbol: dpa

Ensembl ID: FBgn0015929

Description: disc proliferation abnormal

Associated with

Activation of atr in response to replication stress
(R-DME-176187)
Activation of the pre-replicative complex
(R-DME-68962)
Assembly of the pre-replicative complex
(R-DME-68867)
Cell cycle
(R-DME-1640170)
Cell cycle, mitotic
(R-DME-69278)
Cell cycle checkpoints
(R-DME-69620)
Dna replication pre-initiation
(R-DME-69002)
G1/s transition
(R-DME-69206)
G2/m checkpoints
(R-DME-69481)
Mitotic g1 phase and g1/s transition
(R-DME-453279)
Orc1 removal from chromatin
(R-DME-68949)
S phase
(R-DME-69242)
Switching of origins to a post-replicative state
(R-DME-69052)
Synthesis of dna
(R-DME-69239)
3'-5' dna helicase activity
(GO:0043138)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Cmg complex
(GO:0071162)
Dna binding
(GO:0003677)
Dna duplex unwinding
(GO:0032508)
Dna helicase activity
(GO:0003678)
Dna replication
(GO:0006260)
Dna replication initiation
(GO:0006270)
Dna strand elongation involved in dna replication
(GO:0006271)
Dna unwinding involved in dna replication
(GO:0006268)
Double-strand break repair via break-induced replication
(GO:0000727)
Mcm complex
(GO:0042555)
Mitotic dna replication initiation
(GO:1902975)
Mitotic spindle organization
(GO:0007052)
Nucleus
(GO:0005634)
Single-stranded dna binding
(GO:0003697)
Single-stranded dna helicase activity
(GO:0017116)

Other Information

Proteins

DNA replication licensing factor MCM4

Genular Protein ID: 3785409821

Symbol: MCM4_DROME

Name: DNA replication licensing factor MCM4

UniProtKB Accession Codes:

Q26454 Q9V4M5

Database IDs:

Citations:

PubMed ID: 7489728

Title: dpa, a member of the MCM family, is required for mitotic DNA replication but not endoreplication in Drosophila.

PubMed ID: 7489728

DOI: 10.1002/j.1460-2075.1995.tb00223.x

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 16798881

Title: Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase.

PubMed ID: 16798881

DOI: 10.1073/pnas.0602400103

PubMed ID: 17372656

Title: An integrated chemical, mass spectrometric and computational strategy for (quantitative) phosphoproteomics: application to Drosophila melanogaster Kc167 cells.

PubMed ID: 17372656

DOI: 10.1039/b617545g

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

PubMed ID: 20122406

Title: Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins.

PubMed ID: 20122406

DOI: 10.1016/j.molcel.2009.12.030

Sequence Information:

Length: 866
Mass: 96610
Checksum: CF6ED69D2ADDA04E
Sequence:

MSSPARSPSV GGATPKQGAR TPTRGIASQD VETPMRMGPG RAVRPSDNIS LPPTSPGNIS 
LPATSPARGL GANMSEIDLS SPLNYGTPSS MGSIRTPRSG IRGTPLRARP DIRTDKRIRQ 
VAIGGGSGLE PIPEKGSETT DPVSESSQAP QLVVWGTNVV VSQCKSKFKS FIMRFIDPSA 
EQDEISENID VNQPLYLQKL EEIHTLEEPY LNLNCAHLKT FDQDLYRQLI CYPQEVIPGF 
DMAINEMFFE RYPAALLEHQ IQVRPFNADK TRNMRSLNPE DMDQLISISG MVIRSSNVIP 
EMREAFFSCN ICSFSTTVEV DRGRINQPTL CTNCNTNHCF RLIHNRSEFT DKQLVKLQES 
PDDMAAGQTP HNVLLYAHND LVDKVQPGDR VTVTGIYRAT PLKTGGLSSS VKSVYKTHVD 
VVHFRKVDNK RLYEDEEGKD HIFPPERVEL LQLLAKKPDI YDRLARAIAP SIYENDDIKK 
GILLQLFGGT KKKHATLGRQ NFRSEIHLLL CGDPGTSKSQ MLQYVFNLVP RSQYTSGRGS 
SAVGLTAYVT KDPETRQLVL QTGALVLADN GVCCIDEFDK MNDSTRSVLH EVMEQQTLSI 
AKAGIICQLN ARTSILAAAN PAESQWNKRK NIIDNVQLPH TLLSRFDLIF LVLDPQDEIF 
DKRLASHLVS LYYVTRHEEE DTMFDMSVLR DYIAYAREHL SPTLSDEAQQ RLIQAYVDMR 
KVGAGRGQIS AYPRQLESLI RLSEAHAKVR LSNQVELLDV EEAWRLHREA LKQSATDPLS 
GKIDVGILTT GLSTAARKKR ADLVAAIKEN LKKKGKVLTV PYQKLFSDIK EGSQIMITRE 
QFEDALKEVQ DEGAIVVMGK NTIRIC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: dpa

Associated with

Other Information

dpa, a member of the MCM family, is required for mitotic DNA replication but not endoreplication in Drosophila. PubMed ID: 7489728

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase. PubMed ID: 16798881

An integrated chemical, mass spectrometric and computational strategy for (quantitative) phosphoproteomics: application to Drosophila melanogaster Kc167 cells. PubMed ID: 17372656

Phosphoproteome analysis of Drosophila melanogaster embryos. PubMed ID: 18327897

Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins. PubMed ID: 20122406