Details for: PGRP SC2

Gene ID: 35862

Symbol: PGRP SC2

Ensembl ID: FBgn0043575

Description: Peptidoglycan recognition protein SC2

Associated with

  • Defense response to bacterium
    (GO:0042742)
  • Immune response
    (GO:0006955)
  • Innate immune response
    (GO:0045087)
  • N-acetylmuramoyl-l-alanine amidase activity
    (GO:0008745)
  • Negative regulation of biosynthetic process of antibacterial peptides active against gram-negative bacteria
    (GO:0002814)
  • Negative regulation of peptidoglycan recognition protein signaling pathway
    (GO:0061060)
  • Peptidoglycan binding
    (GO:0042834)
  • Peptidoglycan catabolic process
    (GO:0009253)
  • Toll receptor ligand protein activation cascade
    (GO:0160032)
  • Zinc ion binding
    (GO:0008270)

Other Information

Genular Protein ID: 1305292860

Symbol: PGSC2_DROME

Name: Peptidoglycan-recognition protein SC2

UniProtKB Accession Codes:

Q9V4X2 Q70PT2 Q70PT3 Q70PT5 Q70PT6

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 4 EC 2 EMBL 12 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 1 GO 9 Gene3D 1 GeneTree 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRO 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 RefSeq 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 14738318

Title: The evolution of parasite recognition genes in the innate immune system: purifying selection on Drosophila melanogaster peptidoglycan recognition proteins.

PubMed ID: 14738318

DOI: 10.1007/s00239-003-2506-6

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 11106397

Title: A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster.

PubMed ID: 11106397

DOI: 10.1073/pnas.97.25.13772

PubMed ID: 12032070

Title: The Toll and Imd pathways are the major regulators of the immune response in Drosophila.

PubMed ID: 12032070

DOI: 10.1093/emboj/21.11.2568

Sequence Information:

  • Length: 184
  • Mass: 19829
  • Checksum: 0F99D04914B07238
  • Sequence:
    • MANKALILLA VLFCAQAVLG VTIISKSEWG GRSATSKTSL ANYLSYAVIH HTAGNYCSTK 
AACITQLQNI QAYHMDSLGW ADIGYNFLIG GDGNVYEGRG WNVMGAHATN WNSKSIGISF 
LGNYNTNTLT SAQITAAKGL LSDAVSRGQI VSGYILYGHR QVGSTECPGT NIWNEIRTWS 
NWKA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.