Details for: shrb

Gene ID: 35933

Symbol: shrb

Ensembl ID: FBgn0086656

Description: shrub

Associated with

Other Information

Genular Protein ID: 1554754449

Symbol: CHM4_DROME

Name: N/A

UniProtKB Accession Codes:

Q8T0Q4 Q9V543

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ComplexPortal 1 DNASU 1 EMBL 2 EnsemblMetazoa 1 FlyBase 1 GO 18 Gene3D 2 GeneTree 1 GenomeRNAi 1 HOGENOM 1 IntAct 1 InterPro 1 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PaxDb 1 Pfam 1 Proteomes 1 Reactome 3 RefSeq 1 SMR 1 STRING 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 16713958

Title: The coiled-coil protein shrub controls neuronal morphogenesis in Drosophila.

PubMed ID: 16713958

DOI: 10.1016/j.cub.2006.03.067

PubMed ID: 22162134

Title: Synergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signal.

PubMed ID: 22162134

DOI: 10.1083/jcb.201104146

PubMed ID: 22389409

Title: The tumour suppressor Lethal (2) giant discs is required for the function of the ESCRT-III component Shrub/CHMP4.

PubMed ID: 22389409

DOI: 10.1242/jcs.097261

PubMed ID: 25804739

Title: Lgd regulates the activity of the BMP/Dpp signalling pathway during Drosophila oogenesis.

PubMed ID: 25804739

DOI: 10.1242/dev.112961

PubMed ID: 25647097

Title: Abscission is regulated by the ESCRT-III protein shrub in Drosophila germline stem cells.

PubMed ID: 25647097

DOI: 10.1371/journal.pgen.1004653

PubMed ID: 33349255

Title: Lethal (2) giant discs (Lgd)/CC2D1 is required for the full activity of the ESCRT machinery.

PubMed ID: 33349255

DOI: 10.1186/s12915-020-00933-x

PubMed ID: 33660341

Title: shrub is required for spermatogenesis of Drosophila melanogaster.

PubMed ID: 33660341

DOI: 10.1002/arch.21779

PubMed ID: 37226981

Title: Cell-intrinsic and -extrinsic roles of the ESCRT-III subunit Shrub in abscission of Drosophila sensory organ precursors.

PubMed ID: 37226981

DOI: 10.1242/dev.201409

PubMed ID: 27452459

Title: Electrostatic Interactions between Elongated Monomers Drive Filamentation of Drosophila Shrub, a Metazoan ESCRT-III Protein.

PubMed ID: 27452459

DOI: 10.1016/j.celrep.2016.06.093

PubMed ID: 28564595

Title: Structural Basis for Regulation of ESCRT-III Complexes by Lgd.

PubMed ID: 28564595

DOI: 10.1016/j.celrep.2017.05.026

Sequence Information:

  • Length: 226
  • Mass: 25444
  • Checksum: 7F51D239B4A1F73D
  • Sequence:
    • MSFFGKMFGG KKEVAPTTGE AIQKLRETEN MLIKKQEFLE AKIEDELNIA RKNASKNKRV 
ALQALKKKKR LEKQLQQIDG TLSTIEMQRE ALESANTNTA VLTTMKNAAD ALKRAHQNMD 
VDKVHDMMDD IAEQQDVARE ISDAISNPVA FGADLDDEDL ERELDELEQE NFDKEIIGIP 
EPTPTLPEAP TEDLPEKAKE KKKATTTTAV EDDDDPDMKQ LLSWSN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.