Details for: AQP4

Gene ID: 361

Symbol: AQP4

Ensembl ID: ENSG00000171885

Description: aquaporin 4

Associated with

Other Information

Genular Protein ID: 66468414

Symbol: AQP4_HUMAN

Name: Aquaporin-4

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7559426

Title: cDNA cloning, gene organization, and chromosomal localization of a human mercurial insensitive water channel. Evidence for distinct transcriptional units.

PubMed ID: 7559426

DOI: 10.1074/jbc.270.39.22907

PubMed ID: 8601457

Title: A water channel closely related to rat brain aquaporin 4 is expressed in acid- and pepsinogen-secretory cells of human stomach.

PubMed ID: 8601457

DOI: 10.1016/0014-5793(96)00092-0

PubMed ID: 8855281

Title: The human AQP4 gene: definition of the locus encoding two water channel polypeptides in brain.

PubMed ID: 8855281

DOI: 10.1073/pnas.93.20.10908

PubMed ID: 16177791

Title: DNA sequence and analysis of human chromosome 18.

PubMed ID: 16177791

DOI: 10.1038/nature03983

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 22328087

Title: Megalencephalic leukoencephalopathy with subcortical cysts protein 1 functionally cooperates with the TRPV4 cation channel to activate the response of astrocytes to osmotic stress: dysregulation by pathological mutations.

PubMed ID: 22328087

DOI: 10.1093/hmg/dds032

PubMed ID: 29055082

Title: Supramolecular aggregation of aquaporin-4 is different in muscle and brain: correlation with tissue susceptibility in neuromyelitis optica.

PubMed ID: 29055082

DOI: 10.1111/jcmm.13401

PubMed ID: 19383790

Title: Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance.

PubMed ID: 19383790

DOI: 10.1073/pnas.0902725106

Sequence Information:

  • Length: 323
  • Mass: 34830
  • Checksum: 1A1600CF0DC11052
  • Sequence:
  • MSDRPTARRW GKCGPLCTRE NIMVAFKGVW TQAFWKAVTA EFLAMLIFVL LSLGSTINWG 
    GTEKPLPVDM VLISLCFGLS IATMVQCFGH ISGGHINPAV TVAMVCTRKI SIAKSVFYIA 
    AQCLGAIIGA GILYLVTPPS VVGGLGVTMV HGNLTAGHGL LVELIITFQL VFTIFASCDS 
    KRTDVTGSIA LAIGFSVAIG HLFAINYTGA SMNPARSFGP AVIMGNWENH WIYWVGPIIG 
    AVLAGGLYEY VFCPDVEFKR RFKEAFSKAA QQTKGSYMEV EDNRSQVETD DLILKPGVVH 
    VIDVDRGEEK KGKDQSGEVL SSV

Genular Protein ID: 880965122

Symbol: V9PBN7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16177791

Title: DNA sequence and analysis of human chromosome 18.

PubMed ID: 16177791

DOI: 10.1038/nature03983

PubMed ID: 24356448

Title: A novel human aquaporin-4 splice variant exhibits a dominant-negative activity: a new mechanism to regulate water permeability.

PubMed ID: 24356448

DOI: 10.1091/mbc.E13-06-0331

Sequence Information:

  • Length: 296
  • Mass: 31826
  • Checksum: 9FFD0614CC3183A2
  • Sequence:
  • MSDRPTARRW GKCGPLCTRE NIMVAFKGVW TQAFWKAVTA EFLAMLIFVL LSLGSTINWG 
    GTEKPLPVDM VLISLCFGLS IATMVQCFGH ISGGHINPAV TVAMVCTRKI SIAKSVFYIA 
    AQCLGAIIGA GILYLVTPPS VVGGLGVTMV HGNLTAGHGL LVELIITFQL VFTIFASCDS 
    KRTDVTGSIA LAIGFSVAIG HLFAIYWVGP IIGAVLAGGL YEYVFCPDVE FKRRFKEAFS 
    KAAQQTKGSY MEVEDNRSQV ETDDLILKPG VVHVIDVDRG EEKKGKDQSG EVLSSV

Genular Protein ID: 3695548233

Symbol: A0A5F9ZHR4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16177791

Title: DNA sequence and analysis of human chromosome 18.

PubMed ID: 16177791

DOI: 10.1038/nature03983

Sequence Information:

  • Length: 352
  • Mass: 38171
  • Checksum: 155A62B8AA624EF4
  • Sequence:
  • MSDRPTARRW GKCGPLCTRE NIMVAFKGVW TQAFWKAVTA EFLAMLIFVL LSLGSTINWG 
    GTEKPLPVDM VLISLCFGLS IATMVQCFGH ISGGHINPAV TVAMVCTRKI SIAKSVFYIA 
    AQCLGAIIGA GILYLVTPPS VVGGLGVTMV HGNLTAGHGL LVELIITFQL VFTIFASCDS 
    KRTDVTGSIA LAIGFSVAIG HLFAINYTGA SMNPARSFGP AVIMGNWENH WIYWVGPIIG 
    AVLAGGLYEY VFCPDVEFKR RFKEAFSKAA QQTKGSYMEV EDNRSQVETD DLILKPGVVH 
    VIDVDRGEEK KGKDQSGEVL SSVXLEDRTE SRQDSLELSS DFLPPIKETD LL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.