Details for: AQP4

Gene ID: 361

Symbol: AQP4

Ensembl ID: ENSG00000171885

Description: aquaporin 4

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 25.5749
    Cell Significance Index: -10.3900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 10.7752
    Cell Significance Index: -10.2900
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 8.5522
    Cell Significance Index: 119.5900
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 1.4524
    Cell Significance Index: 16.1400
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 0.9831
    Cell Significance Index: 10.4500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.8242
    Cell Significance Index: 50.6600
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 0.7935
    Cell Significance Index: 13.7200
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 0.5123
    Cell Significance Index: 3.0700
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 0.4894
    Cell Significance Index: 8.3700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.4856
    Cell Significance Index: 11.6500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.2159
    Cell Significance Index: 163.4100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1565
    Cell Significance Index: 31.3900
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: 0.1081
    Cell Significance Index: 1.7500
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 0.0598
    Cell Significance Index: 0.4600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0283
    Cell Significance Index: 3.3000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0236
    Cell Significance Index: 8.4800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0126
    Cell Significance Index: 0.8500
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0004
    Cell Significance Index: -0.2800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0038
    Cell Significance Index: -7.1100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0045
    Cell Significance Index: -2.0300
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.0052
    Cell Significance Index: -0.0600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0052
    Cell Significance Index: -9.5300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0056
    Cell Significance Index: -8.6700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0066
    Cell Significance Index: -8.9600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0161
    Cell Significance Index: -11.9400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0170
    Cell Significance Index: -9.3000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0182
    Cell Significance Index: -11.5900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0188
    Cell Significance Index: -11.7700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0208
    Cell Significance Index: -11.7100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0255
    Cell Significance Index: -3.7100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0280
    Cell Significance Index: -8.0600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0404
    Cell Significance Index: -8.0100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0496
    Cell Significance Index: -8.9500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0515
    Cell Significance Index: -5.2600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0518
    Cell Significance Index: -2.7000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0566
    Cell Significance Index: -11.9300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0597
    Cell Significance Index: -3.7600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0597
    Cell Significance Index: -8.2100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0618
    Cell Significance Index: -7.6000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0727
    Cell Significance Index: -12.4100
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0734
    Cell Significance Index: -3.1900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0748
    Cell Significance Index: -9.6700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0878
    Cell Significance Index: -6.7400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0919
    Cell Significance Index: -10.5300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0936
    Cell Significance Index: -9.7500
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: -0.0967
    Cell Significance Index: -1.1200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1138
    Cell Significance Index: -5.9800
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: -0.1284
    Cell Significance Index: -1.2700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1305
    Cell Significance Index: -9.7300
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.1381
    Cell Significance Index: -3.3700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1506
    Cell Significance Index: -7.0200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1519
    Cell Significance Index: -12.0300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1576
    Cell Significance Index: -6.9700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1934
    Cell Significance Index: -10.8500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2031
    Cell Significance Index: -7.6900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2044
    Cell Significance Index: -6.5100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2070
    Cell Significance Index: -7.2500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2114
    Cell Significance Index: -9.9400
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.2138
    Cell Significance Index: -2.8500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2183
    Cell Significance Index: -6.2300
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.2186
    Cell Significance Index: -2.5500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2227
    Cell Significance Index: -7.2900
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2749
    Cell Significance Index: -10.0900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2842
    Cell Significance Index: -4.8700
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.2988
    Cell Significance Index: -3.2800
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.3025
    Cell Significance Index: -6.5400
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.3037
    Cell Significance Index: -3.9300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.3042
    Cell Significance Index: -15.8000
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.3221
    Cell Significance Index: -6.5600
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.3225
    Cell Significance Index: -8.0500
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: -0.3284
    Cell Significance Index: -3.8700
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.3332
    Cell Significance Index: -10.5400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.3397
    Cell Significance Index: -6.8200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3400
    Cell Significance Index: -10.8900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3468
    Cell Significance Index: -9.1200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.3482
    Cell Significance Index: -7.3900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.3557
    Cell Significance Index: -4.2400
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.3599
    Cell Significance Index: -9.1700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.3604
    Cell Significance Index: -10.0700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.3627
    Cell Significance Index: -10.4000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3639
    Cell Significance Index: -12.6500
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.3672
    Cell Significance Index: -7.2600
  • Cell Name: glial cell (CL0000125)
    Fold Change: -0.3697
    Cell Significance Index: -4.0500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.3809
    Cell Significance Index: -5.4600
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.3833
    Cell Significance Index: -8.0000
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.3909
    Cell Significance Index: -8.3600
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.3976
    Cell Significance Index: -9.9300
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.4053
    Cell Significance Index: -6.5700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.4064
    Cell Significance Index: -9.3900
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.4237
    Cell Significance Index: -8.3400
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.4281
    Cell Significance Index: -5.4900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4287
    Cell Significance Index: -12.6300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.4344
    Cell Significance Index: -11.6400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.4359
    Cell Significance Index: -11.6400
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.4367
    Cell Significance Index: -10.8900
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.4417
    Cell Significance Index: -10.7000
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.4635
    Cell Significance Index: -4.4100
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.4725
    Cell Significance Index: -6.4800
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.4730
    Cell Significance Index: -9.4300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Structure:** AQP4 is a homotetramer composed of four identical subunits, each consisting of six transmembrane alpha-helices. 2. **Expression:** AQP4 is primarily expressed in astrocytes, but also found in other cell types, including erythrocytes, type I pneumocytes, and megakaryocytes. 3. **Function:** AQP4 functions as a water channel, allowing for the selective transport of water and small solutes across cell membranes. 4. **Regulation:** AQP4 is regulated by various factors, including vasopressin, which is involved in renal water homeostasis and can also modulate AQP4 expression in the CNS. **Pathways and Functions:** 1. **Aquaporin-mediated transport:** AQP4 facilitates the transport of water and small solutes across cell membranes, maintaining water homeostasis in the CNS and other organs. 2. **Astrocyte end-foot:** AQP4 is involved in the regulation of astrocyte end-foot function, which is critical for maintaining the blood-brain barrier and regulating the extracellular environment. 3. **Cerebrospinal fluid circulation:** AQP4 is thought to play a role in the regulation of cerebrospinal fluid (CSF) circulation, which is essential for maintaining brain volume and function. 4. **Intracellular water homeostasis:** AQP4 helps regulate intracellular water levels, which is critical for maintaining cellular function and homeostasis. **Clinical Significance:** 1. **Cerebral edema:** AQP4 has been implicated in the pathogenesis of cerebral edema, a condition characterized by the accumulation of fluid in the brain. 2. **Multiple sclerosis:** AQP4 has been shown to be overexpressed in patients with multiple sclerosis, a demyelinating disease of the CNS. 3. **Autoimmune disorders:** AQP4 has been implicated in various autoimmune disorders, including autoimmune encephalomyelitis and lupus nephritis. 4. **Renal water homeostasis:** AQP4 plays a critical role in renal water homeostasis, and dysregulation of AQP4 has been implicated in various renal disorders. In conclusion, AQP4 is a crucial protein that plays a pivotal role in maintaining water homeostasis and regulating immune responses in the CNS. Its dysregulation has been implicated in various pathological processes, making it a promising target for the development of novel therapeutics. Further research is needed to fully elucidate the mechanisms of AQP4 and its clinical significance.

Genular Protein ID: 66468414

Symbol: AQP4_HUMAN

Name: Aquaporin-4

UniProtKB Accession Codes:

P55087 P78564

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChEBI 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 17 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRINTS 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 2 RefSeq 2 Rhea 1 SIGNOR 1 SMR 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 7559426

Title: cDNA cloning, gene organization, and chromosomal localization of a human mercurial insensitive water channel. Evidence for distinct transcriptional units.

PubMed ID: 7559426

DOI: 10.1074/jbc.270.39.22907

PubMed ID: 8601457

Title: A water channel closely related to rat brain aquaporin 4 is expressed in acid- and pepsinogen-secretory cells of human stomach.

PubMed ID: 8601457

DOI: 10.1016/0014-5793(96)00092-0

PubMed ID: 8855281

Title: The human AQP4 gene: definition of the locus encoding two water channel polypeptides in brain.

PubMed ID: 8855281

DOI: 10.1073/pnas.93.20.10908

PubMed ID: 16177791

Title: DNA sequence and analysis of human chromosome 18.

PubMed ID: 16177791

DOI: 10.1038/nature03983

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 22328087

Title: Megalencephalic leukoencephalopathy with subcortical cysts protein 1 functionally cooperates with the TRPV4 cation channel to activate the response of astrocytes to osmotic stress: dysregulation by pathological mutations.

PubMed ID: 22328087

DOI: 10.1093/hmg/dds032

PubMed ID: 29055082

Title: Supramolecular aggregation of aquaporin-4 is different in muscle and brain: correlation with tissue susceptibility in neuromyelitis optica.

PubMed ID: 29055082

DOI: 10.1111/jcmm.13401

PubMed ID: 19383790

Title: Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance.

PubMed ID: 19383790

DOI: 10.1073/pnas.0902725106

PubMed ID: 37143309

Title: Aquaporin-4 and GPRC5B: old and new players in controlling brain oedema.

PubMed ID: 37143309

DOI: 10.1093/brain/awad146

Sequence Information:

  • Length: 323
  • Mass: 34830
  • Checksum: 1A1600CF0DC11052
  • Sequence:
    • MSDRPTARRW GKCGPLCTRE NIMVAFKGVW TQAFWKAVTA EFLAMLIFVL LSLGSTINWG 
GTEKPLPVDM VLISLCFGLS IATMVQCFGH ISGGHINPAV TVAMVCTRKI SIAKSVFYIA 
AQCLGAIIGA GILYLVTPPS VVGGLGVTMV HGNLTAGHGL LVELIITFQL VFTIFASCDS 
KRTDVTGSIA LAIGFSVAIG HLFAINYTGA SMNPARSFGP AVIMGNWENH WIYWVGPIIG 
AVLAGGLYEY VFCPDVEFKR RFKEAFSKAA QQTKGSYMEV EDNRSQVETD DLILKPGVVH 
VIDVDRGEEK KGKDQSGEVL SSV

Genular Protein ID: 880965122

Symbol: V9PBN7_HUMAN

Name: N/A

UniProtKB Accession Codes:

V9PBN7

Database IDs:

ARBA 13 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 GO 5 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 1 SAM 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16177791

Title: DNA sequence and analysis of human chromosome 18.

PubMed ID: 16177791

DOI: 10.1038/nature03983

PubMed ID: 24356448

Title: A novel human aquaporin-4 splice variant exhibits a dominant-negative activity: a new mechanism to regulate water permeability.

PubMed ID: 24356448

DOI: 10.1091/mbc.E13-06-0331

Sequence Information:

  • Length: 296
  • Mass: 31826
  • Checksum: 9FFD0614CC3183A2
  • Sequence:
    • MSDRPTARRW GKCGPLCTRE NIMVAFKGVW TQAFWKAVTA EFLAMLIFVL LSLGSTINWG 
GTEKPLPVDM VLISLCFGLS IATMVQCFGH ISGGHINPAV TVAMVCTRKI SIAKSVFYIA 
AQCLGAIIGA GILYLVTPPS VVGGLGVTMV HGNLTAGHGL LVELIITFQL VFTIFASCDS 
KRTDVTGSIA LAIGFSVAIG HLFAIYWVGP IIGAVLAGGL YEYVFCPDVE FKRRFKEAFS 
KAAQQTKGSY MEVEDNRSQV ETDDLILKPG VVHVIDVDRG EEKKGKDQSG EVLSSV

Genular Protein ID: 3695548233

Symbol: A0A5F9ZHR4_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A5F9ZHR4

Database IDs:

ARBA 13 Antibodypedia 1 Bgee 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 1 SAM 2 SUPFAM 1 VEuPathDB 1 iPTMnet 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16177791

Title: DNA sequence and analysis of human chromosome 18.

PubMed ID: 16177791

DOI: 10.1038/nature03983

Sequence Information:

  • Length: 352
  • Mass: 38171
  • Checksum: 155A62B8AA624EF4
  • Sequence:
    • MSDRPTARRW GKCGPLCTRE NIMVAFKGVW TQAFWKAVTA EFLAMLIFVL LSLGSTINWG 
GTEKPLPVDM VLISLCFGLS IATMVQCFGH ISGGHINPAV TVAMVCTRKI SIAKSVFYIA 
AQCLGAIIGA GILYLVTPPS VVGGLGVTMV HGNLTAGHGL LVELIITFQL VFTIFASCDS 
KRTDVTGSIA LAIGFSVAIG HLFAINYTGA SMNPARSFGP AVIMGNWENH WIYWVGPIIG 
AVLAGGLYEY VFCPDVEFKR RFKEAFSKAA QQTKGSYMEV EDNRSQVETD DLILKPGVVH 
VIDVDRGEEK KGKDQSGEVL SSVXLEDRTE SRQDSLELSS DFLPPIKETD LL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.