Nup188 | FBgn0033766 | NCBI 36397

Details for: Nup188

Gene ID: 36397

Symbol: Nup188

Ensembl ID: FBgn0033766

Description: Nucleoporin 188kDa

Associated with

Cell cycle
(R-DME-1640170)
Cell cycle, mitotic
(R-DME-69278)
Gene expression (transcription)
(R-DME-74160)
Gene silencing by rna
(R-DME-211000)
Metabolism of proteins
(R-DME-392499)
Metabolism of rna
(R-DME-8953854)
Mitotic anaphase
(R-DME-68882)
Mitotic metaphase and anaphase
(R-DME-2555396)
Mitotic prophase
(R-DME-68875)
M phase
(R-DME-68886)
Nuclear envelope (ne) reassembly
(R-DME-2995410)
Nuclear envelope breakdown
(R-DME-2980766)
Nuclear pore complex (npc) disassembly
(R-DME-3301854)
Post-translational protein modification
(R-DME-597592)
Postmitotic nuclear pore complex (npc) reformation
(R-DME-9615933)
Processing of capped intron-containing pre-mrna
(R-DME-72203)
Sumo e3 ligases sumoylate target proteins
(R-DME-3108232)
Sumoylation
(R-DME-2990846)
Sumoylation of chromatin organization proteins
(R-DME-4551638)
Sumoylation of dna damage response and repair proteins
(R-DME-3108214)
Sumoylation of dna replication proteins
(R-DME-4615885)
Sumoylation of sumoylation proteins
(R-DME-4085377)
Transcriptional regulation by small rnas
(R-DME-5578749)
Transport of mature mrna derived from an intron-containing transcript
(R-DME-159236)
Transport of mature mrna derived from an intronless transcript
(R-DME-159231)
Transport of mature mrnas derived from intronless transcripts
(R-DME-159234)
Transport of mature transcript to cytoplasm
(R-DME-72202)
Transport of the slbp dependant mature mrna
(R-DME-159230)
Transport of the slbp independent mature mrna
(R-DME-159227)
Nuclear pore inner ring
(GO:0044611)
Nuclear pore organization
(GO:0006999)
Protein import into nucleus
(GO:0006606)
Rna export from nucleus
(GO:0006405)
Structural constituent of nuclear pore
(GO:0017056)

Other Information

Proteins

NU188_DROME

Genular Protein ID: 241238144

Symbol: NU188_DROME

Name: N/A

UniProtKB Accession Codes:

A0A0B4K859 A1Z945

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 32275884

Title: Bi-allelic loss-of-function variants in NUP188 cause a recognizable syndrome characterized by neurologic, ocular, and cardiac abnormalities.

PubMed ID: 32275884

DOI: 10.1016/j.ajhg.2020.03.009

Sequence Information:

Length: 1866
Mass: 213609
Checksum: 49DBDE970924508F
Sequence:

MPAVEKSVIT DWKRLWPMVS GIHYETPQDT VREELMNVAS ELQAGVLQFK PKNASSLELG 
TLLKEKKQEK LLPFTERLQD LLDLESAQCW EILCYYLTQE YRGSASLLTQ LISTETNMAK 
LHEDIRHYYS LERMVVLKIV KNLIVFHQVP NHPYHREYRA VVEKITIPRL RDSYLDQLES 
LICEVPPRKL MAGECFHSAE RLVAWSERNA REINEVLHIL LVLAEHLPMG LEQIKRIFAA 
CKQHSFGKMQ SYLDDSQPYH QEIIRSLSYS ELMLVLKCLD FEKPEKHSDL IEKLIEDLQV 
DIASMYHRPE HGPLLLAWML LRLRGTNDAD DASSLLRCRQ LGKRAVDLKC FVQLHLIARH 
SMYADDSMLS RIVRRTIYNQ VGYLCDLFDG DGSCARYEGI YELLCELVSW PHLAKDFCSR 
EDDGPCSLYK TLLENFPLEL THLSKLALSL TKAGQGNYVK SQLEALPILA LRYDESQHKL 
REVDTNEFEL LASVQPFQQI DFTIPAGTSC TAIQHPSGCF MHFRFPVNYF DALHHEINCL 
LRETGHLHGD FESSERIRNV EAGLRFLESA VKLSQSISGI SAEMVHPTEM CVDLLHTFKS 
VQYPPVGLLS SCLNVCTALL PLVDEEIFSR ISNLHILPTV SPGSHYDFKM YANANGVGFE 
SRFLGSVIDN VEKKRERYEF LLSYIGFLRA YSNLKRNRQI QMEIPGLIFL LKDVFPHLHT 
WHFSSQVERN KIYFEILSFI CDILDLFNTA KESNCKQREL LVKVCVYSLL NLENGLILLR 
FVGVGNAYVQ YTMELETNWM QQQPHGLMML VRLSMRILMQ LLRLKEEVYG NSETLSPLEA 
LIYTQPKQRD TLRIIPTVCS YMSNIFDRWL PILSCRLLKR IALQFNMSLL ACLDMEADQI 
RLTFMQKLPD ELESDSIKIA ILELVDACIA KQPGVTEAFF KVNYALDKRS RSFFSKDCVP 
NIGESIVTYM RDFLDALQVD PLTIQQALPA KIMTIFHSMW KHNLQMLVDD LVKDKQFWKK 
LCSPLFSELQ PNLRIYTQLL NIISIEVYTG NGNNAALLDV MNKFFEQKNF GPWLNYVFNM 
PKVPAVKNLS SSDHLPDWIC CLQAFKDLIV ILLKKQPKFV TIPESQFKLM AQKCLVVLVD 
RSNYLEDMRP FIILAELYVF ILLEFKHAYT DSLEEEQTLM DLLLQLMNRI CACYEDQHVR 
AKEACLAIVT KCTHLYTDLL IRDSSIALRF LNSVVGIICS ELQHMENSVS LEKSQGLNNS 
DSSDSKTSTN SLILCLNLLK AVATIFHNDG PGNWDLPFVS VRLFQRLVRC VSRTLPLFSK 
QVLSVQLLDV LIVFAKGHCS VEFLHCDVGE YLWLKLLPPR ELLQSKHEFT KTTAADAEGW 
TVEQWWPVYA RGIELVTIIY EKHKKCFLED AFQFVGIHAV FLEDALLLSK QSLEPSAMYL 
IKAAVNLVAS LTEHHKEWKQ DSDLSLANLM RAVQSLLCHT SSLFHQQKNL KCLLAGRRSQ 
LEILRSTEAL IVDDELISAC NDLTDIIISC VKALLRFSPD LMELLCCSAY EPSKHSILLD 
VKFGAPKLNE ENLTLTFGIV LNLVNIYVKA LNMQNHGFSE VPLNSLPNVE HSGDNDDPEV 
CVGNQTNRTF SKPLSNVSIS TGTCPASELL SNMDGQLCLL ALEHLLMLVA SQAICIIRSP 
NLETLWKQIV RRDISNELLI FNEFVRRKVI LDYKENRSPW LRRKHGLCKL KCVDPVRSSS 
SSSRSSEIVR RSNTNNELRV NVVRRLHLQQ QQRTPPPQNF DMSSDLSPIA AAQGAAMTTS 
LDGRKRLYPA QQAGDAFLED ELAAIELQYF PPPTEPGYCE LSQVQVVEED YLQLMSALFN 
VMPHCD

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.